Research Labs

The Aromolaran Laboratory

The Aromolaran Laboratory focuses on elucidating how normal cardiac electrical and biophysical properties are altered in obesity and associated pathologies (diabetes, inflammation and lipotoxicity). Obesity is an important contributor to…

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The Blackwood Laboratory

Heart disease is the leading cause of mortality in the US and is often preceded by pathological cardiac hypertrophy due to chronic hypertension and sustained increases in cardiac afterload. While…

The Chaudhuri Laboratory

The Chaudhuri Laboratory’s research is investigate how cardiac metabolism is altered in heart failure, and use these discoveries to seek new therapeutic interventions. Heart disease remains the leading cause of…

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The Dosdall Laboratory

The Dosdall Laboratory uses a combination of mapping techniques to understand the tissue level substrate remodeling that occurs in conditions such as chronic atrial fibrillation, heart failure, and myocardial infarct…

The Cardiac Recovery Laboratory

The Drakos Laboratory’s research is focused on cardiac recovery associated with unloading and mechanical circulatory support (MCS) in the chronic heart failure (HF) setting and the acute setting (i.e. acute…

The Franklin Laboratory

The Franklin Laboratory’s research is focused on the nucleus, DNA is wrapped around histone proteins (i.e. nucleosomes). This combination of DNA, histones and other proteins is referred to as chromatin…

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The Guo Laboratory

The Guo Laboratory’s research is focused on deciphering the pathogenicity of genetic variants in cardiovascular diseases. With the development of medical genetics and low-cost, rapid DNA sequencing technologies, a large…

The Hoareau Laboratory

The Hoareau’s Resuscitation and Cellular Pathobiology Laboratory focuses on studying cellular responses to ischemia and mitigating the negative effects of trauma, particularly after severe blood losses. A particular area of…

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The Hong Laboratory

The Hong Laboratory focuses on understanding the regulation and remodeling of membrane microdomains of cardiomyocytes during heart failure progression. We study how cardiomyocyte surface microdomains are organized to concentrate ion…

The MacLeod Laboratory

The Computational Electrocardiology Laboratory’s research studies electrocardiographic mapping of the heart and body surface. Specific research areas includes cardiac electrophysiology in the study of acute ischemia and repolarization abnormalities; and…