CVRTI Cardiac Research Publications

2023

• Drakos SG, Badolia R, Makaju A, Kyriakopoulos CP, Wever-Pinzon O, Tracy CM, Bakhtina A, Bia R, Parnell T, Taleb I, Ramadurai DKA, Navankasattusas S, Dranow E, Hanff TC, Tseliou E, Shankar TS, Visker J, Hamouche R, Stauder EL, Caine WT, Alharethi R, Selzman CH, Franklin S. DDistinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support. Circulation. 2023 Jan 31;147(5):409-424.
• Junedh M. Amrute, Lulu Lai, Pan Ma, Andrew L. Koenig, Kenji Kamimoto, Andrea Bredemeyer, Thirupura S. Shankar, Christoph Kuppe, Farid F. Kadyrov, Linda J. Schulte, Dylan Stoutenburg, Benjamin J. Kopecky, Sutip Navankasattusas, Joseph Visker, Samantha A. Morris, Rafael Kramann, Florian Leuschner, Douglas L. Mann, Stavros G. Drakos & Kory J. Lavine Defining cardiac functional recovery in end-stage heart failure at single-cell resolution Nature Cardiovascular Research, In Press
• Thohan V, Abraham J, Burdorf A, Sulemanjee N, Jaski B, Guglin M, Pagani FD, Vidula H, Majure DT, Napier R, Heywood TJ, Cogswell R, Dirckx N, Farrar DJ, Drakos SG; Use of a Pulmonary Artery Pressure Sensor to Manage Patients With Left Ventricular Assist Devices. INTELLECT 2-HF Investigators. Circ Heart Fail. 2023 Apr 20.

2022

• Mankouski A, Miller TA, Dodson RB, Yu B, Yang Y, Liu J, Machin DR, Donato AJ, McKnight RA, Zinkhan EK. Large artery stiffening and mortality in a rat model of early vascular remodeling induced by intrauterine growth restriction and a high‐fat diet. Physiological reports. 2022 Dec;10(23):e15518.
• Tracy M Frech, Colin Maguire, Aaron C Petrey, Gregory J Stoddard, Anthony J Donato, A systemic sclerosis disease model: can inducible pluripotent stem cells fill an unmet need in defining vascular leak?, Rheumatology, 2022
• Bloom, S.I., Tucker, J.R., Lim, J. et al. Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions. GeroScience 44, 2741–2755 (2022). https://doi.org/10.1007/s11357-022-00681-6
• Bloom SI, Islam MT, Lesniewski LA, Donato AJ. Mechanisms and consequences of endothelial cell senescence. Nature Reviews Cardiology. 2022 Jul 19:1-4.
• Gogulamudi VR, Machin DR, Henson GD, Lim J, Bramwell RC, Durrant JR, Donato AJ, Lesniewski LA. Sirt1 overexpression attenuates Western‐style diet‐induced aortic stiffening in mice. Physiological Reports. 2022 May;10(9):e15284.
• Pierce GL, Coutinho TA, DuBose LE, Donato AJ. Is it good to have a stiff aorta with aging? Causes and consequences. Physiology. 2022 May 1;37(3):154-73.
• Machin DR, Clifton HL, Wray DW, Frech TM, Donato AJ. Tetrahydrobiopterin Administration Augments Exercise-Induced Hyperemia and Endothelial Function in Patients With Systemic Sclerosis. Frontiers in Medicine. 2022 Jan 10;8:791689.
• Wohlfahrt P, Nativi-Nicolau J, Zhang M, Selzman CH, Greene T, Conte J, Biber JE, Hess R, Mondesir FL, Wever-Pinzon O, Drakos SG, Gilbert EM, Kemeyou L, LaSalle B, Steinberg BA, Shah RU, Fang JC, Spertus JA, Stehlik J (2022). Quality of Life in Patients With Heart Failure With Recovered Ejection Fraction. JAMA Cardiol, 6(8), 957-962.
• Orkild BA, Zenger B, Iyer K, Rupp L, Ibrahim M, Khashani A, Perez M, Foote M, Bergquist J, Morris A, Kim J, Steinberg B, Selzman C, Ratcliffe M, MacLeod RS, Elhabian S, Morgan AE*. All Roads Lead to Rome: Diverse Etiologies of Tricuspid Regurgitation Create a Predictable Constellation of Right Ventricular Shape Changes. Frontiers in Physiology, 2022.
• Schuler S, Schaufelberger M, Bear LR, Bergquist JA, Cluitmans MJM, Coll-Font J, Onak ON, Zenger B, Loewe A, MacLeod RS, Brooks DH, Dossel O. Reducing Line-of-Block Artifacts in Cardiac Activation Maps Estimated Using ECG Imaging: A Comparison of Source Models and Estimation Methods. IEEE Transactions on Biomedical Engineering 2022 ; 69 6 : 2041-2052.
• Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D. Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment. Nat. Commun., 2022.
• Nowadly CD, Johnson MA, Youngquist ST, Williams TK, Neff LP, Hoareau GL Automated aortic endovascular balloon volume titration prevents re-arrest immediately after return of spontaneous circulation in a swine model of nontraumatic cardiac arrest. Resusc Plus.
• Odunayo A, Alwood A, Asokan V, Balakrishnan A, Berkowitz S, Buckley G, Chih A. Claus K, Cottam E, Gonzalez A, Hoareau GL, Holowavchuk M, Johnson P Kielb J. Ngwenyama T, Pardo M, Rutter C, Sharpe S, Whitehead K. Our quest for creating a space that is welcoming to all: A commentary from the American College of Veterinary Emergency and Critical Care Diversity, Equity, and Inclusion Committee. J Vet Emerg Crit Care. 2022 Feb 27
• Bergquist JA, Coll-Font J, Zenger B, Rupp LC, Good WW, Brooks DH, MacLeod RS. Reconstruction of cardiac position using body surface potentials. Computers in biology and medicine 2022 ; 142 : 105174
• Shimura D, Hunter J, Katsumara M, Shaw RM. Removal of an Internal Translational Start Site from mRNA While Retaining Expression of the Full-Length Protein. JoVE 2022;March 16: doi: 10.3791/63405.
• Eberhardt DR, Lee SH, Yin X, Balynas AM, Rekate E, Kraiss JN, Lang MJ, Walsh MA, Streiff ME, Corbin AC, Funai K, Sachse FB, Chaudhuri D. EFHD1 ablation inhibits cardiac mitoflash activation and protects cardiomyocytes from ischemia. J Mol Cell Cardiol. 2022. doi: 10.1016/j.yjmcc.2022.03.002. PMID: 35304170
• Sommakia, S., N.H. Almaw, S.H. Lee, D.K.A. Ramadurai, I. Taleb, C.P. Kyriakopoulos, C.J. Stubben, J. Ling, R.A. Campbell, R.A. Alharethi, W.T. Caine, S. Navankasattusas, G.L. Hoareau, A.E. Abraham, J.C. Fang, C.H. Selzman, S.G. Drakos, and D. Chaudhuri, FGF21 (Fibroblast Growth Factor 21) Defines a Potential Cardiohepatic Signaling Circuit in End-Stage Heart Failure.Circ Heart Fail, 2022. 15(3): p. e008910, PMC8930477, PMID 34865514.
• Son SL, Hosek LL, Stein MC, Allshouse AA, Catino AB, Hoskoppal AK, Cox DA, Whitehead KJ, Lindsay IM, Esplin S, Metz TD. Association between pregnancy and long-term cardiac outcomes in individuals with congenital heart disease. Am J Obstet Gynecol. 2022 Jan;226(1):124.e1-124.e8. doi: 10.1016/j.ajog.2021.07.015. Epub 2021 Jul 28. PubMed PMID: 34331895; PubMed Central PMCID: PMC8748281.

2021

• Lange M, Hirahara AM, Ranjan R, Stoddard GJ, Dosdall DJ (2021). Atrial slow conduction develops and dynamically expands during premature stimulation in an animal model of persistent atrial fibrillation. PLoS One, 16(10), e0258285.v
• Frank B Sachse, Robert W Hitchcock, Nassir F Marrouche, Nathan J Knighton, Chao Huang. Devices, systems, and methods for imaging and treating a selected tissue. US Patent 11,154,186. 2021
• Carley AN, Maurya SK, Fasano M, Wang Y, Selzman CH, Drakos SG, Lewandowski ED. Short Chain Fatty Acids Outpace Ketone Oxidation in the Failing Heart. Circulation. 2021 Feb 19.
• Maron BA, Wang RS, Shevtsov S, Drakos SG, Arons E, Wever-Pinzon O, Huggins GS, Samokhin AO, Oldham WM, Aguib Y, Yacoub MH, Rowin EJ, Maron BJ, Maron MS, Loscalzo J. Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes. Nat Commun. 2021 Feb 8;12(1):873.
• Thirupura S Shankar, Dinesh Kumar Anandamurugan Ramadurai, Kira Steinhorst, Salah Sommakia, Rachit Badolia, ASPASIA SPYRIDOULA THODOU KROKIDI, Dallen Calder, Sutip Navankasattusas, Jing Ling, Ohyun Kwon, Emily Cheng, Russel Richardson, Frank B Sachse, Johann Schredelseker, Kenneth Spitzer, Dipayan Chaudhuri, Stavros G Drakos. Abstract P467: Cardiac-specific Deletion Of Voltage Dependent Anion Channel 2 Leads To Dilated Cardiomyopathy By Altering Calcium Homeostasis. Circulation Research 129 (Suppl_1), AP467-AP467c
• Michio Sato, Tsuyoshi Kadomatsu, Keishi Miyata, Junco Wddcarren, Zhe Tian, Shunshun Zhu, Haruki Horiguchi, Aman Makaju, Anna Bakhtina, Jun Morinaga, Taichi Sugizaki, Kaname Hirashima, Kumiko Yoshinobu, Mai Imasaka, Masatake Araki, Yoshihiro Komohara, Tomohiko Wakayama, Shinichi Nakagawa, Sarah Franklin, Koichi Node, Kimi Araki, and Yuichi Oike. The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis.  Nature Communications (accepted)
• João Salinet, Rubén Molero, Fernando Soares Schlindwein, Joël Karel, Miguel Rodrigo, José Luis Rojo-Álvarez, Omer Berenfeld, Andreu Climent, Brian Zenger, Frederique Jos Vanheusden, Jimena Gabriela Siles Paredes, Rob MacLeod, Felipe Atienza, María S Guillem, Matthijs Cluitmans, Pietro Bonizzi. “Electrocardiographic imaging for atrial fibrillation: a perspective from computer models and animal experiments to clinical value “ Frontiers in Physiology (EP) (accepted)
• DS Li, EA Mendiola, R Avazmohammadi, FB Sachse, MS Sacks. A Large-scale 3D Micromechanical Computational Myocardium Mode. 2021
• Khan, Muhammad S., Shaw, Robin M. “Huntington’s disease skeletal muscle has altered T-tubules” JGP Journal of General Physiology, Online Issn: 1540-7748, Print Issn: 0022-1295, 12 May 2021
• Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette K, Angel N, Chou D, Plank G, MacLeod RS. JCombining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study.ournal of electrocardiology 2021 ;
• Good WW, Gillette KK, Zenger B, Bergquist JA, Rupp LC, Tate J, Anderson D, Gsell MAF, Plank G, MacLeod RS。Estimation and Validation of Cardiac Conduction Velocity and Wavefront Reconstruction Using Epicardial and Volumetric Data.IEEE transactions on bio-medical engineering 2021 ; 68 11 : 3290-3300
• Shaw RM, “Ion Channel Trafficking in the Heart” CARDIAC ELECTROPHYSIOLOGY: From Cell to Bedside, 8/E., 2021, ed. Zipes DP, Jalife J.
• Pacheco C, Wei J, Shufelt C, Hitzeman TC, Cook-Wiens G, Pepine CJ, Handberg E, Anderson RD, Petersen JW, Hong T, Shaw RM, Bairey Merz CN. Association of coronary microvascular dysfunction and cardiac bridge integrator 1, a cardiomyocyte dysfunction biomarker. Clin Cardiol 2021 (in press)
• Nathan J. Knighton, Brian K. Cottle, Sarthak Tiwari, Abhijit Mondal, Aditya K. Kaza, Frank B. Sachse, Robert W. Hitchcock. Toward cardiac tissue characterization using machine learning and light-scattering spectroscopy. J. of Biomedical Optics, 26(11), 116001 (2021).
• Delisle BP, Aromolaran AS. (2021). Editorial: Perturbations in Metabolic Cues: Implications for Adverse Cardiac Function Leading to Sudden Cardiac Death. Front Physiol. 12, doi: 10.3389/fphys.2021.788904. PMID: 34867488; PMCID: PMC8634259 
• Aromolaran AS (2021). Is there an emerging role for IKs in aging-related ventricular arrhythmias? J Cell Physiol. Dec 8. doi: 10.1002/jcp.30658. 
• DeAngelo MM, Peacock JB, Holeman TA, Maloney M, Beckstrom J, Brooke BS. Long-Term Functional Decline Following Vascular Surgery Among Vulnerable Adults. Ann Vasc Surg. 2021 Oct;76:87-94. doi: 10.1016/j.avsg.2021.04.002. Epub 2021 Apr 22. PubMed PMID: 33895257; PubMed Central PMCID: PMC8531166.
• Healy AH, Bowen M, McKellar SH, Koliopoulou A, Drakos SG, Selzman CH (2021). Interleukin-1 Receptor Antagonism as Adjunct Therapy for Heart Failure Patients with Left Ventricular Assist Devices. ASAIO J, 67(8), e145-e147.
• David R Eberhardt, Sandra H Lee, Xue Yin, Anthony M Balynas, Emma Rekate, Jackie N Kraiss, Marisa J Lang, Maureen A Walsh, Molly E Streiff, Andrea C Corbin, Katsuhiko Funai, Frank B Sachse, Dipayan Chaudhuri. EFHD1 ablation reduces cardiac mitoflash activation and protects cardiomyocytes from ischemia. bioRxiv. 2021
• Chowdhury KH, Martinez-Mateu L, Do J, Aromolaran KA, Saiz J, Aromolaran AS (2021). Macrophage-Dependent Interleukin-6-Production and Inhibition of I_KContributes to Acquired QT Prolongation in Lipotoxic Guinea Pig Heart. Int J Mol Sci, 22(20).
• Javan H, Li L, Schaaf CL, Lee YS, Salama ME, Dinarello CA, Selzman CH (2021). Interleukin 1 receptor antagonism abrogates acute pressure-overload induced murine heart failure. Ann Thorac Surg.
• Diakos NA, Taleb I, Kyriakopoulos CP, Shah KS, Javan H, Richins TJ, Yin MY, Yen CG, Dranow E, Bonios MJ, Alharethi R, Koliopoulou AG, Taleb M, Fang JC, Selzman CH, Stellos K, Drakos SG (2021). Circulating and Myocardial Cytokines Predict Cardiac Structural and Functional Improvement in Patients With Heart Failure Undergoing Mechanical Circulatory Support. J Am Heart Assoc, 10(20), e020238.
• Aparna C Sankarankutty, Joachim Greiner, Jean Bragard, Joseph R Visker, Thirupura S Shankar, Christos P Kyriakopoulos, Stavros G Drakos, Frank B Sachse. Etiology-Specific Remodeling in Ventricular Tissue of Heart Failure Patients and Its Implications for Computational Modeling of Electrical Conduction. Frontiers in physiology 12. 2021
• Shimura D, Nuebel E, Baum R, Valdez SE, Xiao S, Warren JS, Palatinus JA, Hong T, Rutter J, Shaw RM. Protective mitochondrial fission induced by stress-responsive protein GJA1-20k. Elife. 2021 Oct 5;10. doi: 10.7554/eLife.69207. PubMed PMID: 34608863; PubMed Central PMCID: PMC8492060.
• Selzman CH, Drakos SG, Chaudhuri D. FGF21 (Fibroblast Growth Factor 21) Defines a Potential Cardiohepatic Signaling Circuit in End-Stage Heart Failure. Circ Heart Fail. 2021 Dec 6;:CIRCHEARTFAILURE121008910. doi: 10.1161/CIRCHEARTFAILURE.121.008910. [Epub ahead of print] PubMed PMID: 34865514; NIHMSID:NIHMS1756360.
• Khan MS, Lange M, Ranjan R, Sharma V, Glotzbach JP, Selzman C, Dosdall DJ (2021). Premature atrial stimulation accentuates conduction abnormalities in cardiac surgery patients that develop postoperative atrial fibrillation. J Electrocardiol, 69, 36-43.
• Shaw RM, Saffitz JE (2021). A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy. J Clin Invest, 130(4), 1608-1610.
• NJ Knighton, BK Cottle, BEB Kelson, RW Hitchcock, FB Sachse. Towards intraoperative quantification of atrial fibrosis using light-scattering spectroscopy and convolutional neural networks. Sensors 21 (18), 6033. 2021
• Kamali R, Kump J, Ghafoori E, Lange M, Hu N, Bunch TJ, Dosdall DJ, Macleod RS, Ranjan R (2021). Area Available for Atrial Fibrillation to Propagate Is an Important Determinant of Recurrence After Ablation. JACC Clin Electrophysiol, 7(7), 896-908.
• Hunt B, Kwan E, McMillan M, Dosdall D, MacLeod R, Ranjan R (2021). Deep Learning Based Prediction of Atrial Fibrillation Disease Progression with Endocardial Electrograms in a Canine Model. Comput Cardiol, 47.
• Shanmugam G, Wang D, Gounder SS, Fernandes J, Litovsky SH, Whitehead K, Radhakrishnan RK, Franklin S, Hoidal JR, Kensler TW, DellItalia L, Darley-Usmar V, Abel ED, Jones DP, Ping P, Rajasekaran NS (2021). Reductive Stress Causes Pathological Cardiac Remodeling and Diastolic Dysfunction. Antioxid Redox Signal, 32(18), 1293-1312.
• Hunt B, Kwan E, McMillan M, Dosdall D, MacLeod R, Ranjan R (2021). Deep Learning Based Prediction of Atrial Fibrillation Disease Progression with Endocardial Electrograms in a Canine Model. Comput Cardiol, 47.
• T. S. Shankar, D. K. A. Ramadurai, K. Steinhorst, S. Sommakia, R. Badolia, A. T. Krokidi, D. Calder, S. Navankasattusas, P. Sander, O. S. Kwon, A. Aravamudhan, J. Ling, A. Dendorfer, C. Xie, O. Kwon, E. Cheng, K. Whitehead, T. Gudermann, R. Richardson, F. B. Sachse, J. Schredelseker, K. Spitzer, D. Chaudhuri, and Stavros Drakos. Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis. Nat Comm, 7(1):1-11, 2021. Published, 07/2021.
• D. S. Li, E. A. Mendiola, R. Avazmohammadi, F. B. Sachse, and M. S. Sacks. A high-fidelity 3d micromechanical model of ventricular myocardium. In D. B. Ennis, L. E. Perotti, and V. Y. Wang, editors, Lecture Notes in Computer Science, 12738, 168-177, 2021. Published, 07/01/2021.
• Y. Lyu, V. K. Verma, Y. Lee, I. Taleb, R. Badolia, T. S. Shankar, C. P. Kyriakopoulos, C. H. Selzman, W. Caine, R. Alharethi, S. Navankasattusas, T. Seidel, S. G. Drakos, and F. B. Sachse. Remodeling of t-system and proteins underlying excitation-contraction coupling in aging versus failing human heart. NPJ Aging and Mechanisms of Disease, 7(1):1-11, 2021. Published, 06/01/2021.
• Selzman CH, Tonna JE, Pierce J, Vargas C, Skidmore C, Lewis G, Hatton ND, Phillips JD (2021). A pilot trial of human amniotic fluid for the treatment of COVID-19. BMC Res Notes, 14(1), 32.
• Hydren JR, Gifford JR, Jarrett CL, Park SH, Shields KL, Broxterman RM, Kithas AC, Bisconti AV, Thurston TS, Ratchford SM, Wray DW, Stehlik J, Selzman CH, Drakos SG, Richardson RS (2021). Vascular Function in Continuous-Flow Left Ventricular Assist Device Recipients: Effect of a Single Pulsatility Treatment Session. (Epub ahead of print) Am J Physiol Regul Integr Comp Physiol.
• Hoffman M, Palioura D, Kyriazis ID, Cimini M, Badolia R, Rajan S, Gao E, Nikolaidis N, Schulze PC, Goldberg IJ, Kishore R, Yang VW, Bannister TD, Bialkowska AB, Selzman CH, Drakos SG, Drosatos K (2021). Cardiomyocyte Krüppel-like Factor 5 Promotes De Novo Ceramide Biosynthesis and Contributes to Eccentric Remodeling in Ischemic Cardiomyopathy. (Epub ahead of print) Circulation.
• Healy AH, Bowen M, McKellar SH, Koliopoulou A, Drakos SG, Selzman CH (2021). Interleukin-1 Receptor Antagonism as Adjunct Therapy for Heart Failure Patients with Left Ventricular Assist Devices. (Epub ahead of print) ASAIO J.
• Musfee FI, Agopian AJ, Goldmuntz E, Hakonarson H, Morrow BE, Taylor DM, Tristani-Firouzi M, Watkins WS, Yandell M, Mitchell LE (2021). Common Variation in Cytoskeletal Genes is Associated with Conotruncal Heart Defects. Genes (Basel), 12(5).
• Gakenheimer-Smith L, Meyers L, Lundahl D, Menon SC, Bunch TJ, Sawyer BL, Tristani-Firouzi M, Etheridge SP (2021). Expanding the phenotype of CACNA1C mutation disorders. Mol Genet Genomic Med, e1673.
• Bernardi J, Aromolaran KA, Zhu H, Aromolaran AS (2021). Circadian Mechanisms: Cardiac Ion Channel Remodeling and Arrhythmias. Front Physiol, 11, 611860.
• Shankar TS, Ramadurai DKA, Steinhorst K, Sommakia S, Badolia R, Thodou Krokidi A, Calder D, Navankasattusas S, Sander P, Kwon OS, Aravamudhan A, Ling J, Dendorfer A, Xie C, Kwon O, Cheng EHY, Whitehead KJ, Gudermann T, Richardson RS, Sachse FB, Schredelseker J, Spitzer KW, Chaudhuri D, Drakos SG. Cardiac-specific deletion of voltage dependent anion channel 2 leads to dilated cardiomyopathy by altering calcium homeostasis. Nat Commun. 2021 Jul 28;12(1):4583. 
• Kamali R, Kump J, Ghafoori E, Lange M, Hu N, Bunch TJ, Dosdall DJ, Macleod RS, Ranjan R. Area Available for Atrial Fibrillation to Propagate Is an Important Determinant of Recurrence After Ablation. JACC. Clinical electrophysiology 2021 ;
• Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette KK, Gsell MAF, Plank G, MacLeod RS. Quantifying the spatiotemporal influence of acute myocardial ischemia on volumetric conduction velocity. Journal of electrocardiology 2021 ; 66 : 86-94
• Bergquist JA, Good WW, Zenger B, Tate JD, Rupp LC, MacLeod RS. The electrocardiographic forward problem: A benchmark study.Computers in biology and medicine 2021 ; 134 : 104476
• Zenger B, Good WW, Bergquist JA, Rupp LC, Perez M, Stoddard GJ, Sharma V, MacLeod RS. Pharmacological and simulated exercise cardiac stress tests produce different ischemic signatures in high-resolution experimental mapping studies. Journal of electrocardiology 2021 ; 68 : 56-64
• Zenger B, Good WW, Bergquist JA, Rupp LC, Perez M, Stoddard GJ, Sharma V, MacLeod RS. Transient recovery of epicardial and torso ST-segment ischemic signals during cardiac stress tests: A possible physiological mechanism. Journal of electrocardiology 2021 ;
• Charlebois CM, Caldwell DJ, Rampersad SM, Janson AP, Ojemann JG, Brooks DH, MacLeod RS, Butson CR, Dorval AD. Validating Patient-Specific Finite Element Models of Direct Electrocortical Stimulation. Frontiers in neuroscience 2021 ; 15 : 691701
• Bergquist JA, Coll-Font J, Zenger B, Rupp LC, Good WW, Brooks DH, MacLeod RS. Simultaneous Multi-Heartbeat ECGI Solution with a Time-Varying Forward Model: a Joint Inverse Formulation.Functional imaging and modeling of the heart : … International Workshop, FIMH …, proceedings. FIMH 2021 ; 12738 : 493-502
• Carley AN, Maurya SK, Fasano M, Wang Y, Selzman CH, Drakos SG, Lewandowski ED (2021). Short-Chain Fatty Acids Outpace Ketone Oxidation in the Failing Heart. Circulation, 143(18), 1797-1808.
• Shah P, Psotka M, Taleb I, Alharethi R, Shams MA, Wever-Pinzon O, Yin M, Latta F, Stehlik J, Fang JC, Diao G, Singh R, Ijaz N, Kyriakopoulos CP, Zhu W, May CW, Cooper LB, Desai SS, Selzman CH, Kfoury AG, Drakos SG (2021). Framework to Classify Reverse Cardiac Remodeling With Mechanical Circulatory Support: The Utah-Inova Stages. Circ Heart Fail, 14(5), e007991.
• Tonna JE, Pierce J, Hatton N, Lewis G, Phillips JD, Messina A, Skidmore CR, Taylor K, Selzman CH (2021). Safety and feasibility of using acellular sterile filtered amniotic fluid as a treatment for patients with COVID-19: protocol for a randomised, double-blinded, placebo-controlled clinical trial. BMJ Open, 11(2), e045162.
• Selzman C (2021). Commentary: Latent hypertrophic obstructive cardiomyopathy-(Un)clear and present danger. J Thorac Cardiovasc Surg.
• Sharma V, Glotzbach JP, Ryan J, Selzman CH (2021). Evaluating Quality in Adult Cardiac Surgery. Tex Heart Inst J, 48(1).

2020

• Li J, Agvanian S, Zhou K, Shaw RM, Hong T (2020). Exogenous Cardiac Bridging Integrator 1 Benefits Mouse Hearts With Pre-existing Pressure Overload-Induced Heart Failure. Front Physiol, 11, 708.
• Glotzbach JP, Selzman CH (2020). Commentary: Recalibrating the eyeball test. J Thorac Cardiovasc Surg, 161(6), 2106-2107.
• Goodwin ML, Selzman CH (2020). Take a load off: Unloading and reperfusion. J Thorac Cardiovasc Surg, 161(6), 2046-2050.
• Hitzeman TC, Xie Y, Zadikany RH, Nikolova AP, Baum R, Caldaruse AM, Agvanian S, Melmed GY, McGovern DPB, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong T, Shaw RM. cBIN1 Score (CS) Identifies Ambulatory HFrEF Patients and Predicts Cardiovascular Events. Front Physiol. 2020;11:503. doi: 10.3389/fphys.2020.00503. eCollection 2020. PubMed PMID: 32670075; PubMed Central PMCID: PMC7326053.
• Li J, Agvanian S, Zhou K, Shaw RM, Hong T. Exogenous Cardiac Bridging Integrator 1 Benefits Mouse Hearts With Pre-existing Pressure Overload-Induced Heart Failure. Front Physiol. 2020;11:708. doi: 10.3389/fphys.2020.00708. eCollection 2020. PubMed PMID: 32670093; PubMed Central PMCID: PMC7327113.
• Xiao S, Shimura D, Baum R, Hernandez DM, Agvanian S, Nagaoka Y, Katsumata M, Lampe PD, Kleber AG, Hong T, Shaw RM. Auxiliary trafficking subunit GJA1-20k protects connexin-43 from degradation and limits ventricular arrhythmias. J Clin Invest. 2020 Sep 1;130(9):4858-4870. doi: 10.1172/JCI134682. PubMed PMID: 32525845; PubMed Central PMCID: PMC7456223.
• Hitzeman TC, Xie Y, Zadikany RH, Nikolova AP, Baum R, Caldaruse AM, Agvanian S, Melmed GY, McGovern DPB, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong T, Shaw RM (2020). cBIN1 Score (CS) Identifies Ambulatory HFrEF Patients and Predicts Cardiovascular Events. Front Physiol, 11, 503.
• Liu Y, Zhou K, Li J, Agvanian S, Caldaruse AM, Shaw S, Hitzeman TC, Shaw RM, Hong T (2020). In Mice Subjected to Chronic Stress, Exogenous cBIN1 Preserves Calcium-Handling Machinery and Cardiac Function. JACC Basic Transl Sci, 5(6), 561-578.
• Epifantseva I, Xiao S, Baum RE, Klber AG, Hong T, Shaw RM (2020). An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression. Biomolecules, 10(3).
• Money JE, Al Danaf J, Nelson M, Mckellar SH, Drakos SG, Kemeyou L (2020). Loss of Pulsatility: Another Cause of Syncope in Patients with Left Ventricular Assist Devices. ASAIO J, 66(10), e128-e130.
• Birks EJ, Drakos SG, Patel SR, Lowes BD, Selzman CH, Starling RC, Trivedi J, Slaughter MS, Atluri P, Goldstein D, Maybaum S, Um JY, Margulies KB, Stehlik J, Cunningham C, Farrar DJ, Rame JE (2020). A Prospective Multicentre Study of Myocardial Recovery Using Left Ventricular Assist Devices (REmission from Stage D Heart Failure: RESTAGE-HF): Medium Term and Primary Endpoint Results. (Epub ahead of print) Circulation.
• Frey C, Koliopoulou AG, Montenont E, Tolley ND, Javan H, McKellar SH, Drakos SG, Selzman CH, Rondina MT (2020). Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading. Platelets, 31(7), 952-959.
• Lobo AS, Sandoval Y, Henriques JP, Drakos SG, Taleb I, Bagai J, Cohen MG, Chatzizisis YS, Sun B, Hryniewicz K, Eckman PM, Thiele H, Brilakis ES (2020). Cardiogenic Shock Management: International Survey of Contemporary Practices. J Invasive Cardiol, 32(10), 371-374.
• Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG (2020). The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure. Circulation, 142(3), 259-274.
• Oka SI, Sabry AD, Horiuchi AK, Cawley KM, OVery SA, Zaitsev MA, Shankar TS, Byun J, Mukai R, Xu X, Torres NS, Kumar A, Yazawa M, Ling J, Taleb I, Saijoh Y, Drakos SG, Sadoshima J, Warren JS (2020). Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1. PLoS ONE, 15(6), e0234913.
• Bunsawat K, Ratchford SM, Alpenglow JK, Park SH, Jarrett CL, Stehlik J, Drakos SG, Richardson RS, Wray DW (2020). Chronic antioxidant administration restores macrovascular function in patients with heart failure with reduced ejection fraction. (Epub ahead of print) Exp Physiol.
• Hydren JR, Cornwell WK 3rd, Richardson RS, Drakos SG (2020). Exercise Capacity in Mechanically Supported Advanced Heart Failure Patients: It Is All About the Beat. ASAIO J, 66(4), 339-342.
• Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED (2020). Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling. JCI Insight, 5(6).
• Money JE, Al Danaf J, Nelson M, Mckellar SH, Drakos SG, Kemeyou L (2020). Loss of Pulsatility: Another Cause of Syncope in Patients with Left Ventricular Assist Devices. (Epub ahead of print) ASAIO J.
• Ko B, Drakos SG, Ibrahim H, Kang TS, Thodou A, Bonios M, Taleb I, Welt FG (2020). Percutaneous Mechanical Unloading Simultaneously With Reperfusion Induces Increased Myocardial Salvage in Experimental Acute Myocardial Infarction. Circ Heart Fail, 13(1), e005893.
• Hirahara AM, Lange M, Shah A, Khan MS, Ranjan R, Stoddard G, Dosdall DJ (2020). His bundle pacing shows similar ventricular electrical activation as sinus: selective and nonselective His pacing indistinguishable. Am J Physiol Heart Circ Physiol, 320(1), H13-H22.
• Kamali R, Schroeder J, DiBella E, Steinberg B, Han F, Dosdall DJ, Macleod RS, Ranjan R (2020). Reproducibility of clinical late gadolinium enhancement magnetic resonance imaging in detecting left atrial scar after atrial fibrillation ablation. J Cardiovasc Electrophysiol, 31(11), 2824-2832.
• Shah AR, Khan MS, Hirahara AM, Lange M, Ranjan R, Dosdall DJ (2020). In Vitro/Ex Vivo Investigation of Modified Utah Electrode Array to Selectively Sense and Pace the Sub-Surface Cardiac His Bundle. ACS Biomater Sci Eng, 6(6), 3335-3348.
• Khan MS, Yamashita K, Sharma V, Ranjan R, Dosdall DJ (2020). RNAs and Gene Expression Predicting Postoperative Atrial Fibrillation in Cardiac Surgery Patients Undergoing Coronary Artery Bypass Grafting. J Clin Med, 9(4).
• Shah AR, Khan MS, Hirahara AM, Lange M, Ranjan R, Dosdall DJ (2020). A real-time system for selectively sensing and pacing the His-bundle during sinus rhythm and ventricular fibrillation. Biomed Eng Online, 19(1), 19.
• Yamashita K, Kwan E, Kamali R, Ghafoori E, Steinberg BA, MacLeod RS, Dosdall DJ, Ranjan R (2020). Blanking period after radiofrequency ablation for atrial fibrillation guided by ablation lesion maturation based on serial MR imaging. J Cardiovasc Electrophysiol, 31(2), 450-456.
• Angel N, Kholmovski EG, Ghafoori E, Dosdall DJ, MacLeod RS, Ranjan R (2020). Regions of High Dominant Frequency in Chronic Atrial Fibrillation Anchored to Areas of Atrial Fibrosis. Comput Cardiol, 46.
• Szulik MW, Davis K, Bakhtina A, Azarcon P, Bia R, Horiuchi E, Franklin S (2020). Transcriptional regulation by methyltransferases and their role in the heart: highlighting novel emerging functionality. Am J Physiol Heart Circ Physiol, 319(4), H847-H865.
• Liu Y, Zhou K, Li J, Agvanian S, Caldaruse AM, Shaw S, Hitzeman TC, Shaw RM, Hong T. In Mice Subjected to Chronic Stress, Exogenous cBIN1 Preserves Calcium-Handling Machinery and Cardiac Function. JACC Basic Transl Sci. 2020 Jun;5(6):561-578. doi: 10.1016/j.jacbts.2020.03.006. PMCID: PMC7315191.
• Li J, Agvanian S, Zhou K, Shaw RM, Hong T. Exogenous Cardiac Bridging Integrator 1 Benefits Mouse Hearts With Pre-existing Pressure Overload-Induced Heart Failure. Front Physiol. 2020;11:708. doi: 10.3389/fphys.2020.00708. PMCID: PMC7327113.
• Hirahara AM, Lange M, Shah A, Khan MS, Ranjan R, Stoddard G, Dosdall DJ (2020). His bundle pacing shows similar ventricular electrical activation as sinus: selective and nonselective His pacing indistinguishable. Am J Physiol Heart Circ Physiol, 320(1), H13-H22.
• Tian Y, Mendes J, Wilson B, Ross A, Ranjan R, DiBella E, Adluru G (2020). Whole-heart, ungated, free-breathing, cardiac-phase-resolved myocardial perfusion MRI by using Continuous Radial Interleaved simultaneous Multi-slice acquisitions at sPoiled steady-state (CRIMP). Magn Reson Med, 84(6), 3071-3087.
• Zenger B, Zhang M, Lyons A, Bunch TJ, Fang JC, Freedman RA, Navaravong L, Piccini JP, Ranjan R, Spertus JA, Stehlik J, Turner JL, Greene T, Hess R, Steinberg BA (2020). Patient-reported outcomes and subsequent management in atrial fibrillation clinical practice: Results from the Utah mEVAL AF program. J Cardiovasc Electrophysiol, 31(12), 3187-3195.
• Kamali R, Schroeder J, DiBella E, Steinberg B, Han F, Dosdall DJ, Macleod RS, Ranjan R (2020). Reproducibility of clinical late gadolinium enhancement magnetic resonance imaging in detecting left atrial scar after atrial fibrillation ablation. J Cardiovasc Electrophysiol, 31(11), 2824-2832.
• Swenson DJ, Taepke RT, Blauer JJE, Kwan E, Ghafoori E, Plank G, Vigmond E, MacLeod RS, DeGroot P, Ranjan R (2020). Direct comparison of a novel antitachycardia pacing algorithm against present methods using virtual patient modeling. Heart Rhythm, 17(9), 1602-1608.
• Shah AR, Khan MS, Hirahara AM, Lange M, Ranjan R, Dosdall DJ (2020). In Vitro/Ex Vivo Investigation of Modified Utah Electrode Array to Selectively Sense and Pace the Sub-Surface Cardiac His Bundle. ACS Biomater Sci Eng, 6(6), 3335-3348.
• Khan MS, Yamashita K, Sharma V, Ranjan R, Dosdall DJ (2020). RNAs and Gene Expression Predicting Postoperative Atrial Fibrillation in Cardiac Surgery Patients Undergoing Coronary Artery Bypass Grafting. J Clin Med, 9(4).
• Shah AR, Khan MS, Hirahara AM, Lange M, Ranjan R, Dosdall DJ (2020). A real-time system for selectively sensing and pacing the His-bundle during sinus rhythm and ventricular fibrillation. Biomed Eng Online, 19(1), 19.
• Yamashita K, Kwan E, Kamali R, Ghafoori E, Steinberg BA, MacLeod RS, Dosdall DJ, Ranjan R (2020). Blanking period after radiofrequency ablation for atrial fibrillation guided by ablation lesion maturation based on serial MR imaging. J Cardiovasc Electrophysiol, 31(2), 450-456.
• Angel N, Kholmovski EG, Ghafoori E, Dosdall DJ, MacLeod RS, Ranjan R (2020). Regions of High Dominant Frequency in Chronic Atrial Fibrillation Anchored to Areas of Atrial Fibrosis. Comput Cardiol, 46.
• A. A. Ahmad, M. Streiff, C. Hunter & F. B. Sachse (2020). Modulation of calcium transients in cardiomyocytes by transient receptor potential canonical 6 channels. Front Physiol. Published, 01/2020.
• Q. Hu, A. A. Ahmad, T. Seidel, C. Hunter, M. Streiff, L. Nikolova, K. W. Spitzer & F. B. Sachse (2020). Location and function of transient receptor potential canonical channel 1 in ventricular myocytes. J Mol Cell Cardiol. Published, 01/2020.
• C. Huang, N. Knighton, L. H. Timmins, and F. B. Sachse. Catheter-based optical approaches for cardiovascular medicine: Progress, challenges and new directions. Prog Biomed Eng, 2(3):032001, 2020. Published, 06/2020.
• J. K. Johnson, B. K. Cottle, A. Mondal, R. Hitchcock, A. K. Kaza, and F. B. Sachse. Localization of the sinoatrial and atrioventricular nodal region in neonatal and juvenile ovine hearts. PLoS One, 15(5):e0232618, 2020. Published, 05/2020.
• A. Kaza, A. Mondal, B. Piekarski, F. B. Sachse, and R. W. Hitchcock. Intraoperative localization of cardiac conduction tissue regions using real-time fibre-optic confocal microscopy: First in human trial. Eur J Cardiothorac Surg, 58(2):261-268, 2020. Published, 08/2020.
• F. B. Sachse, J. K. Johnson, B. K. Cottle, A. Mondal, R. Hitchcock, and A. K. Kaza. Towards detection of conduction tissue during cardiac surgery: Light at the end of the tunnel? Heart Rhythm, 17(20):2200-2207, 2020. Published, 12/2020.
• Moore B, Morgan N, Selzman C, Zimmerman J (2020). Successful Use of Limited Transthoracic Echocardiography to Guide Veno-venous Extracorporeal Membrane Oxygenator Placement in a Patient With Coronavirus Disease 2019. J Cardiothorac Vasc Anesth, 34(12), 3491-3493.
• Birks EJ, Drakos SG, Patel SR, Lowes BD, Selzman CH, Starling RC, Trivedi J, Slaughter MS, Alturi P, Goldstein D, Maybaum S, Um JY, Margulies KB, Stehlik J, Cunningham C, Farrar DJ, Rame JE (2020). Prospective Multicenter Study of Myocardial Recovery Using Left Ventricular Assist Devices (RESTAGE-HF [Remission from Stage D Heart Failure]): Medium-Term and Primary End Point Results. Circulation, 142(21), 2016-2028.
• Frey C, Koliopoulou AG, Montenont E, Tolley ND, Javan H, McKellar SH, Drakos SG, Selzman CH, Rondina MT (2020). Longitudinal assessment of the platelet transcriptome in advanced heart failure patients following mechanical unloading. Platelets, 31(7), 952-959.
• Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG (2020). The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure. Circulation, 142(3), 259-274.
• Tonna JE, Selzman CH, Girotra S, Presson AP, Thiagarajan RR, Becker LB, Zhang C, Keenan HT, American Heart Associations Get With the GuidelinesResuscitation Investigators (2020). Patient and Institutional Characteristics Influence the Decision to Use Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest. J Am Heart Assoc, 9(9), e015522.
• Tonna JE, McKellar SH, Selzman CH, Drakos S, Koliopoulou AG, Taleb I, Stoddard GJ, Stehlik J, Welt FGP, Fair JF 3rd, Stoddard K, Youngquist ST (2020). Exploratory analysis of myocardial function after extracorporeal cardiopulmonary resuscitation vs conventional cardiopulmonary resuscitation. BMC Res Notes, 13(1), 137.
• Kirklin JK, Pagani FD, Goldstein DJ, John R, Rogers JG, Atluri P, Arabia FA, Cheung A, Holman W, Hoopes C, Jeevanandam V, John R, Jorde UP, Milano CA, Moazami N, Naka Y, Netuka I, Pagani FD, Pamboukian SV, Pinney S, Rogers JG, Selzman CH, Silverstry S, Slaughter M, Stulak J, Teuteberg J, Vierecke J, Schueler S, DAlessandro DA (2020). American Association for Thoracic Surgery/International Society for Heart and Lung Transplantation guidelines on selected topics in mechanical circulatory support. J Thorac Cardiovasc Surg, 159(3), 865-896.
• Wohlfahrt P, Zickmund SL, Slager S, Allen LA, Nicolau JN, Kfoury AG, Felker GM, Conte J, Flint K, DeVore AD, Selzman CH, Hess R, Spertus JA, Stehlik J (2020). Provider Perspectives on the Feasibility and Utility of Routine Patient-Reported Outcomes Assessment in Heart Failure: A Qualitative Analysis. J Am Heart Assoc, 9(2), e013047.
• Morton SU, Shimamura A, Newburger PE, Opotowsky AR, Quiat D, Pereira AC, Jin SC, Gurvitz M, Brueckner M, Chung WK, Shen Y, Bernstein D, Gelb BD, Giardini A, Goldmuntz E, Kim RW, Lifton RP, Porter GA Jr, Srivastava D, Tristani-Firouzi M, Newburger JW, Seidman JG, Seidman CE (2020). Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease. JAMA Cardiol, 6(4), 457-462.
• Martin-Trujillo A, Patel N, Richter F, Jadhav B, Garg P, Morton SU, McKean DM, DePalma SR, Goldmuntz E, Gruber D, Kim R, Newburger JW, Porter GA Jr, Giardini A, Bernstein D, Tristani-Firouzi M, Seidman JG, Seidman CE, Chung WK, Gelb BD, Sharp AJ (2020). Rare genetic variation at transcription factor binding sites modulates local DNA methylation profiles. PLoS Genet, 16(11), e1009189.
• Sharma A, Wasson LK, Willcox JA, Morton SU, Gorham JM, DeLaughter DM, Neyazi M, Schmid M, Agarwal R, Jang MY, Toepfer CN, Ward T, Kim Y, Pereira AC, DePalma SR, Tai A, Kim S, Conner D, Bernstein D, Gelb BD, Chung WK, Goldmuntz E, Porter G, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE, Pediatric Cardiac Genomics Consortium (2020). GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm. eLife, 9.
• Shah RU, Mutharasan RK, Ahmad FS, Rosenblatt AG, Gay HC, Steinberg BA, Yandell M, Tristani-Firouzi M, Klewer J, Mukherjee R, Lloyd-Jones DM (2020). Development of a Portable Tool to Identify Patients With Atrial Fibrillation Using Clinical Notes From the Electronic Medical Record. Circ Cardiovasc Qual Outcomes, 13(10), e006516.
• Richter F, Morton SU, Kim SW, Kitaygorodsky A, Wasson LK, Chen KM, Zhou J, Qi H, Patel N, DePalma SR, Parfenov M, Homsy J, Gorham JM, Manheimer KB, Velinder M, Farrell A, Marth G, Schadt EE, Kaltman JR, Newburger JW, Giardini A, Goldmuntz E, Brueckner M, Kim R, Porter GA Jr, Bernstein D, Chung WK, Srivastava D, Tristani-Firouzi M, Troyanskaya OG, Dickel DE, Shen Y, Seidman JG, Seidman CE, Gelb BD (2020). Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nat Genet, 52(8), 769-777.
• Boskovski MT, Homsy J, Nathan M, Sleeper LA, Morton S, Manheimer KB, Tai A, Gorham J, Lewis M, Swartz M, Alfieris GM, Bacha EA, Karimi M, Meyer D, Nguyen K, Bernstein D, Romano-Adesman A, Porter GA Jr, Goldmuntz E, Chung WK, Srivastava D, Kaltman JR, Tristani-Firouzi M, Lifton R, Roberts AE, Gaynor JW, Gelb BD, Kim R, Seidman JG, Brueckner M, Mayer JE Jr, Newburger JW, Seidman CE (2020). De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease. Circ Genom Precis Med, 13(4), e002836.
• Lpez-Serrano AL, De Jess-Prez JJ, Zamora-Crdenas R, Ferrer T, Rodrguez-Menchaca AA, Tristani-Firouzi M, Moreno-Galindo EG, Navarro-Polanco RA (2020). Voltage-induced structural modifications on M2 muscarinic receptor and their functional implications when interacting with the superagonist iperoxo. Biochem Pharmacol, 177, 113961.
• Hsieh A, Morton SU, Willcox JAL, Gorham JM, Tai AC, Qi H, DePalma S, McKean D, Griffin E, Manheimer KB, Bernstein D, Kim RW, Newburger JW, Porter GA Jr, Srivastava D, Tristani-Firouzi M, Brueckner M, Lifton RP, Goldmuntz E, Gelb BD, Chung WK, Seidman CE, Seidman JG, Shen Y (2020). EM-mosaic detects mosaic point mutations that contribute to congenital heart disease. Genome Medicine, 12(1), 42.
• Edwards JJ, Rouillard AD, Fernandez NF, Wang Z, Lachmann A, Shankaran SS, Bisgrove BW, Demarest B, Turan N, Srivastava D, Bernstein D, Deanfield J, Giardini A, Porter G, Kim R, Roberts AE, Newburger JW, Goldmuntz E, Brueckner M, Lifton RP, Seidman CE, Chung WK, Tristani-Firouzi M, Yost HJ, Maayan A, Gelb BD (2020). Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects. JACC Basic Transl Sci, 5(4), 376-386.
• Bayrak CS, Zhang P, Tristani-Firouzi M, Gelb BD, Itan Y (2020). De novo variants in exomes of congenital heart disease patients identify risk genes and pathways. Genet Med, In Press.
• Bernardi J, Aromolaran KA, Aromolaran AS (2020). Neurological Disorders and Risk of Arrhythmia. Int J Mol Sci, 22(1).
• Van Keuren AM, Tsai CW, Balderas E, Rodriguez MX, Chaudhuri D, Tsai MF. Mechanisms of EMRE-Dependent MCU Opening in the Mitochondrial Calcium Uniporter Complex. Cell Rep. 2020
• Lam PY, Thawani AR, Balderas E, White AJP, Chaudhuri D, Fuchter MJ, Peterson RT. TRPswitch-A Step-Function Chemo-optogenetic Ligand for the Vertebrate TRPA1 Channel. J Am Chem Soc. 2020 Oct 14;142(41):17457-17468. doi: 10.1021/jacs.0c06811. Epub 2020 Oct 5.
• Badolia R, Ramadurai DKA, Abel ED, Ferrin P, Taleb I, Shankar TS, Krokidi AT, Navankasattusas S, McKellar SH, Yin M, Kfoury AG, Wever-Pinzon O, Fang JC, Selzman CH, Chaudhuri D, Rutter J, Drakos SG. The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure. Circulation. 2020 
• Yao C, Bora SA, Parimon T, Zaman T, Friedman OA, Palatinus JA, Surapaneni NS, Matusov YP, Cerro Chiang G, Kassar AG, Patel N, Green CER, Aziz AW, Suri H, Suda J, Lopez AA, Martins GA, Stripp BR, Gharib SA, Goodridge HS, Chen P. Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients. Cell Rep. 2021 Jan 5;
• Yamashita K, Kwan E, Kamali R, Ghafoori E, Steinberg BA, MacLeod RS, Dosdall DJ, Ranjan R. Blanking Period after Radiofrequency Ablation for Atrial Fibrillation guided by Ablation Lesion Maturation based on Serial MR Imaging.Journal of cardiovascular electrophysiology 2020 ;
• Zenger B, Good WW, Bergquist JA, Burton BM, Tate JD, Berkenbile L, Sharma V, MacLeod RS. Novel experimental model for studying the spatiotemporal electrical signature of acute myocardial ischemia: a translational platform.Physiological measurement 2020 ; 41 1 : 015002
• Yamashita K, Kamali R, Kwan E, MacLeod RS, Dosdall DJ, Ranjan R. Effective Ablation Settings That Predict Chronic Scar After Left Atrial Ablation. JACC. Clinical electrophysiology 2020 ; 6 2 : 143-152
• Swenson DJ, Taepke RT, Blauer JJ, Kwan E, Ghafoori E, Plank G, Vigmond E, MacLeod RS, DeGroot P, Ranjan R. A Direct Comparison of a Novel Antitachycardia Pacing Algorithm Against Present Methods Using Virtual Patient Modeling. Heart rhythm 2020 ;
• Kamali R, Schroeder J, DiBella E, Steinberg B, Han F, Dosdall DJ, Macleod RS, Ranjan R. Reproducibility of Clinical Late Gadolinium Enhancement Magnetic Resonance Imaging in Detecting Left Atrial Scar after Atrial Fibrillation Ablation. Journal of cardiovascular electrophysiology 2020 ;
• Good WW, Erem B, Zenger B, Coll-Font J, Bergquist JA, Brooks DH, MacLeod RS. Characterizing the transient electrocardiographic signature of ischemic stress using Laplacian Eigenmaps for dimensionality reduction. Computers in biology and medicine 2020 ; 127 : 104059
• Morgan AE, Kashani A, Zenger B, Rupp LC, Perez MD, Foote MD, Morris AK, Ratcliffe MB, Kim JJ, Weinsaft JW, Sharma V, MacLeod RS, Elhabian S. Right Ventricular Shape Distortion in Tricuspid Regurgitation. Computing in cardiology 2020 ; 47 :
• Rupp LC, Good WW, Bergquist JA, Zenger B, Gillette K, Plank G, MacLeod RS. Effect of Myocardial Fiber Direction on Epicardial Activation Patterns. Computing in cardiology 2020 ; 47;
• Zenger B, Bergquist JA, Good WW, Rupp LC, MacLeod RS. Experimental Validation of a Novel Extracellular-Based Source Representation of Acute Myocardial Ischemia.Computing in cardiology 2020 ; 47 ;
• Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette K, Plank G, MacLeod RS. Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds.Computing in cardiology 2020 ; 47;
• Bergquist JA, Coll-Font J, Zenger B, Rupp LC, Good WW, Brooks DH, MacLeod RS. Improving Localization of Cardiac Geometry Using ECGI.Computing in cardiology 2020 ; 47
• Bergquist JA, Zenger B, Good WW, Rupp LC, Bear LR, MacLeod RS. Novel Experimental Preparation to Assess Electrocardiographic Imaging Reconstruction Techniques.Computing in cardiology 2020 ; 47;
• FB Sachse, J Johnson, B Cottle, A Mondal, R Hitchcock, AK Kaza. Toward detection of conduction tissue during cardiac surgery: Light at the end of the tunnel?
• Heart rhythm 17 (12), 2200-2207. 2020

• ME Streiff, AA Ahmad, C Hunter, FB Sachse. Spatial Arrangement of TRPC1, 3 and 6 Channels in Rabbit Ventricular Cardiomyocytes
• Biophysical Journal 118 (3), 415a. 2020

• Zenger B, Bergquist JA, Good WW, Steadman B, MacLeod RS. High-Capacity Cardiac Signal Acquisition System for Flexible, Simultaneous, Multidomain Acquisition.Computing in cardiology 2020 ; 47;
• FB Sachse, RW Hitchcock, NF Marrouche, NJ Knighton, C Huang. Devices and methods for mapping cardiac tissue. US Patent App. 16/482,389. 2020

2019

• Nikolova AP, Hong T, Shaw RM. Letter by Nikolova et al Regarding Article, “Heart Failure With Preserved Ejection Fraction in Perspective”. Circ Res. 2019 Aug 2;125(4):e24-e25. doi: 10.1161/CIRCRESAHA.119.315583. Epub 2019 Aug 1. PubMed PMID: 31518204; PubMed Central PMCID: PMC7266620.
• Xiao S, Shimura D, Baum R, Hernandez DM, Agvanian S, Nagaoka Y, Katsumata M, Lampe PD, Kleber AG, Hong T, Shaw RM (2019). Auxiliary trafficking subunit GJA1-20k protects connexin-43 from degradation and limits ventricular arrhythmias. J Clin Invest, 130(9), 4858-4870.
• Shaw RM (2019). Correlating Cardiac Origin Neurohormonal Stress Levels With Heart Failure Outcomes. JAMA Cardiol, 5(3), 326-327.
• Taleb I, Wever-Pinzon J, Wang W, Koliopoulou A, Dranow E, Yu T, Yin L, McKellar SH, Stehlik J, Fang JC, Wever-Pinzon O, Selzman CH, Drakos SG (2019). Outcomes of Asian-Americans Implanted With Left Ventricular Assist Devices: An Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Analysis. Heart, Lung & Circulation, 29(8), 1226-1233.
• Yin MY, Strege J, Gilbert EM, Stehlik J, McKellar SH, Elmer A, Anderson T, Aljuaid M, Nativi-Nicolau J, Koliopoulou AG, Davis E, Fang JC, Drakos SG, Selzman CH, Wever-Pinzon O (2019). Impact of Shared Care in Remote Areas for Patients With Left Ventricular Assist Devices. JACC Heart Fail, 8(4), 302-312.
• Hydren JR, Kithas AC, Park SH, Wever-Pinzon O, Selzman CH, Perry W, Vargas CAS, Stehlik J, Drakos SG, Richardson RS (2019). Targeting Peripheral Vascular Pulsatility in Heart Failure Patients with Continuous-Flow Left Ventricular Assist Devices: The Impact of Pump Speed. ASAIO J, 66(3), 291-299.
• Yin MY, Wever-Pinzon O, Mehra MR, Selzman CH, Toll AE, Cherikh WS, Nativi-Nicolau J, Fang JC, Kfoury AG, Gilbert EM, Kemeyou L, McKellar SH, Koliopoulou A, Vaduganathan M, Drakos SG, Stehlik J (2019). Post-transplant outcome in patients bridged to transplant with temporary mechanical circulatory support devices. J Heart Lung Transplant, 38(8), 858-869.
• Symons JD, Deeter L, Deeter N, Bonn T, Cho JM, Ferrin P, McCreath L, Diakos NA, Taleb I, Alharethi R, McKellar S, Wever-Pinzon O, Navankasattusas S, Selzman CH, Fang JC, Drakos SG (2019). Effect of Continuous-Flow Left Ventricular Assist Device Support on Coronary Artery Endothelial Function in Ischemic and Nonischemic Cardiomyopathy. Circ Heart Fail, 12(8), e006085.
• Iosif Taleb, Antigone G Koliopoulou, Anwar Tandar, Stephen H McKellar, Joseph E Tonna, Jose Nativi-Nicolau, Miguel Alvarez Villela, Frederick Welt, Josef Stehlik, Edward M Gilbert, Omar Wever-Pinzon, Jack H Morshedzadeh, Elizabeth Dranow, Craig H Selzman, James C Fang, Stavros G Drakos (2019). Shock Team Approach in Refractory Cardiogenic Shock Requiring Short-Term Mechanical Circulatory Support. Circ Heart Fail, 140(1), 98-100.
• Uriel N, Burkhoff D, Rich JD, Drakos SG, Teuteberg JJ, Imamura T, Rodgers D, Raikhelkar J, Vorovich EE, Selzman CH, Kim G, Sayer G (2019). Impact of Hemodynamic Ramp Test-Guided HVAD Speed and Medication Adjustments on Clinical Outcomes. Circ Heart Fail, 12(4), e006067.
• Khan MS, Yamashita K, Sharma V, Ranjan R, Selzman CH, Dosdall DJ (2019). Perioperative Biomarkers Predicting Postoperative Atrial Fibrillation Risk After Coronary Artery Bypass Grafting: A Narrative Review. J Cardiothorac Vasc Anesth, 34(7), 1933-1941.
• Yamashita K, Kamali R, Kwan E, MacLeod RS, Dosdall DJ, Ranjan R (2019). Effective Ablation Settings That Predict Chronic Scar After Left Atrial Ablation. JACC Clin Electrophysiol, 6(2), 143-152.
• Reno CM, Bayles J, Huang Y, Oxspring M, Hirahara AM, Dosdall DJ, Fisher SJ (2019). Severe Hypoglycemia-Induced Fatal Cardiac Arrhythmias Are Mediated by the Parasympathetic Nervous System in Rats. Diabetes, 68(11), 2107-2119.
• Yamashita K, Silvernagel J, Kwan E, Kamali R, Ghafoori E, MacLeod R, Dosdall DJ, Ranjan R (2019). Changes in atrial electrophysiological and structural substrate and their relationship to histology in a long-term chronic canine atrial fibrillation model. Pacing Clin Electrophysiol, 42(7), 930-936.
• Cullar J, Ludlam WG, Tensmeyer NC, Aoba T, Dhavale M, Santiago C, Bueno-Carrasco MT, Mann MJ, Plimpton RL, Makaju A, Franklin S, Willardson BM, Valpuesta JM (2019). Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly. Nat Commun, 10(1), 2865.
• Ludlam WG, Aoba T, Cullar J, Bueno-Carrasco MT, Makaju A, Moody JD, Franklin S, Valpuesta JM, Willardson BM (2019). Molecular architecture of the Bardet-Biedl syndrome protein 2-7-9 subcomplex. J Biol Chem, 294(44), 16385-16399.
• Khan MS, Yamashita K, Sharma V, Ranjan R, Selzman CH, Dosdall DJ (2019). Perioperative Biomarkers Predicting Postoperative Atrial Fibrillation Risk After Coronary Artery Bypass Grafting: A Narrative Review. J Cardiothorac Vasc Anesth, 34(7), 1933-1941.
• Steinberg BA, Turner J, Lyons A, Biber J, Chelu MG, Fang JC, Freedman RA, Han FT, Hardisty B, Marrouche NF, Ranjan R, Shah RU, Spertus JA, Stehlik J, Zenger B, Piccini JP, Hess R (2019). Systematic collection of patient-reported outcomes in atrial fibrillation: feasibility and initial results of the Utah mEVAL AF programme. Europace, 22(3), 368-374.
• Yamashita K, Kamali R, Kwan E, MacLeod RS, Dosdall DJ, Ranjan R (2019). Effective Ablation Settings That Predict Chronic Scar After Left Atrial Ablation. JACC Clin Electrophysiol, 6(2), 143-152.
• Yamashita K, Ghafoori E, Silvernagel J, Ashton J, J Dosdall D, MacLeod R, Ranjan R (2019). The Effective Contact Force to Minimize Edema Relative to Chronic Lesion Formation During Radiofrequency Ablation in Ventricular Wall. Int Heart J, 60(6), 1407-1414.
• Getman MK, Wissner E, Ranjan R, Lalonde JP (2019). Relationship between time-to-isolation and freeze duration: Computational modeling of dosing for Arctic Front Advance and Arctic Front Advance Pro cryoballoons. J Cardiovasc Electrophysiol, 30(11), 2274-2282.
• Yamashita K, Silvernagel J, Kwan E, Kamali R, Ghafoori E, MacLeod R, Dosdall DJ, Ranjan R (2019). Changes in atrial electrophysiological and structural substrate and their relationship to histology in a long-term chronic canine atrial fibrillation model. Pacing Clin Electrophysiol, 42(7), 930-936.
• J. Bragard, A. Sankarankutty, and F. B. Sachse. Extended bidomain modeling of defibrillation: Quantifying virtual electrode strengths in fibrotic myocardium. Front Physiol, 10:337, 2019. Published, 04/2019.
• D. Colli, S. Blood, A. Sankarankutty, F. B. Sachse, M. Frisk, W. Louch, and P. Kekenes-Huskey. A matched-filter based algorithm for subcellular classification of t-system in cardiac tissues. Biophys J, 116(8):1386-93, 2019. Published, 04/2019.
• A. Mondal, J. Lackey, M. Saed, F.-Y. Wu, J. Johnson, C. Huang, F. Sachse, R. Hitchcock, and A. Kaza. An imaging protocol to discriminate specialized conduction tissue during congenital heart surgery. Semin Thorac Cardiovasc Surg, 2019. Epub Feb 6. Published, 04/2019.
• A. C. Sankarankutty, S. Navankasattusa, I. Taleb, W. T. Caine, R. Alharethi, C. H. Selzman, S. Drakos & F. B. Sachse (2019). Intra-subject and inter-subject variability in remodeling of cardiac tissues of heart failure patients. Uncertainty Quantification for Cardiac Models. Published, 06/2019.
• M. Streiff, A. A. Ahmad, C. Hunter & F. B. Sachse (2019). Super-resolution imaging of TRPC1 channels in ventricular cardiomyocytes. Proc Cardiac Mechano-Electric Coupling and Arrhythmias. Published, 09/2019.
• B. D. Wilson, S. L. Wasmund, F. B. Sachse, G. Kaur, N. F. Marrouche, and L. A. Cannon-Albright. Evidence for a heritable contribution to atrial fibrillation associated with fibrosis. JACC Clin Electrophysiol, 5(4):493-500, 2019. Published, 04/2019.
• C. Huang, S. L. Wasmund, T. Yamaguchi, N. Knighton, R. W. Hitchcock, I. A. Polejaeva, K. L. White, N. F. Marrouche, and F. B. Sachse. Towards automated quantification of atrial fibrosis in images from catheterized fiber-optics confocal microscopy using convolutional neural networks. In Y. Coudiere, V. Ozenne, E. Vigmond, and N. Zemzemi, editors, Lecture Notes in Computer Science, volume 11504, pages 168-76. Springer, 2019. Published, 04/2019.
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• Sharma V, DeShazo RA, Skidmore CR, Glotzbach JP, Koliopoulou A, Javan H, McKellar SH, Powell DL, Selzman CH (2019). Surgical explantation of atrial septal closure devices for refractory nickel allergy symptoms. J Thorac Cardiovasc Surg, 160(2), 502-509.e1.
• Taleb I, Wever-Pinzon J, Wang W, Koliopoulou A, Dranow E, Yu T, Yin L, McKellar SH, Stehlik J, Fang JC, Wever-Pinzon O, Selzman CH, Drakos SG (2019). Outcomes of Asian-Americans Implanted With Left Ventricular Assist Devices: An Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Analysis. Heart, Lung & Circulation, 29(8), 1226-1233.
• Khan MS, Yamashita K, Sharma V, Ranjan R, Selzman CH, Dosdall DJ (2019). Perioperative Biomarkers Predicting Postoperative Atrial Fibrillation Risk After Coronary Artery Bypass Grafting: A Narrative Review. J Cardiothorac Vasc Anesth, 34(7), 1933-1941.
• Yin MY, Strege J, Gilbert EM, Stehlik J, McKellar SH, Elmer A, Anderson T, Aljuaid M, Nativi-Nicolau J, Koliopoulou AG, Davis E, Fang JC, Drakos SG, Selzman CH, Wever-Pinzon O (2019). Impact of Shared Care in Remote Areas for Patients With Left Ventricular Assist Devices. JACC Heart Fail, 8(4), 302-312.
• Sharma V, DeShazo RA, Skidmore CR, Glotzbach JP, Koliopoulou A, Javan H, McKellar SH, Powell DL, Selzman CH (2019). Surgical explantation of atrial septal closure devices for refractory nickel allergy symptoms. J Thorac Cardiovasc Surg, 160(2), 502-509.e1.
• Taleb I, Wever-Pinzon J, Wang W, Koliopoulou A, Dranow E, Yu T, Yin L, McKellar SH, Stehlik J, Fang JC, Wever-Pinzon O, Selzman CH, Drakos SG (2019). Outcomes of Asian-Americans Implanted With Left Ventricular Assist Devices: An Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Analysis. Heart, Lung & Circulation, 29(8), 1226-1233.
• Khan MS, Yamashita K, Sharma V, Ranjan R, Selzman CH, Dosdall DJ (2019). Perioperative Biomarkers Predicting Postoperative Atrial Fibrillation Risk After Coronary Artery Bypass Grafting: A Narrative Review. J Cardiothorac Vasc Anesth, 34(7), 1933-1941.
• Yin MY, Strege J, Gilbert EM, Stehlik J, McKellar SH, Elmer A, Anderson T, Aljuaid M, Nativi-Nicolau J, Koliopoulou AG, Davis E, Fang JC, Drakos SG, Selzman CH, Wever-Pinzon O (2019). Impact of Shared Care in Remote Areas for Patients With Left Ventricular Assist Devices. JACC Heart Fail, 8(4), 302-312.
• Hydren JR, Kithas AC, Park SH, Wever-Pinzon O, Selzman CH, Perry W, Vargas CAS, Stehlik J, Drakos SG, Richardson RS (2019). Targeting Peripheral Vascular Pulsatility in Heart Failure Patients with Continuous-Flow Left Ventricular Assist Devices: The Impact of Pump Speed. ASAIO J, 66(3), 291-299.
• Bowen ME, Selzman CH, McKellar SH (2019). Right Ventricular Involution: Big Changes in Small Hearts. J Surg Res, 243, 255-264.
• Pepin ME, Drakos S, Ha CM, Tristani-Firouzi M, Selzman CH, Fang JC, Wende AR, Wever-Pinzon O (2019). DNA methylation reprograms cardiac metabolic gene expression in end-stage human heart failure. Am J Physiol Heart Circ Physiol, 317(4), H674-H684.
• Pires KM, Torres NS, Buffolo M, Gunville R, Schaaf C, Davis K, Selzman CH, Gottlieb RA, Boudina S (2019). Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling. Antioxid Redox Signal, 31(6), 444-457.
• Yin MY, Wever-Pinzon O, Mehra MR, Selzman CH, Toll AE, Cherikh WS, Nativi-Nicolau J, Fang JC, Kfoury AG, Gilbert EM, Kemeyou L, McKellar SH, Koliopoulou A, Vaduganathan M, Drakos SG, Stehlik J (2019). Post-transplant outcome in patients bridged to transplant with temporary mechanical circulatory support devices. J Heart Lung Transplant, 38(8), 858-869.
• Symons JD, Deeter L, Deeter N, Bonn T, Cho JM, Ferrin P, McCreath L, Diakos NA, Taleb I, Alharethi R, McKellar S, Wever-Pinzon O, Navankasattusas S, Selzman CH, Fang JC, Drakos SG (2019). Effect of Continuous-Flow Left Ventricular Assist Device Support on Coronary Artery Endothelial Function in Ischemic and Nonischemic Cardiomyopathy. Circ Heart Fail, 12(8), e006085.
• DeBoard ZM, Varghese TK Jr, Doty JR, Selzman CH (2019). Cardiothoracic Surgery Residency Training in Surgical Ablation for Atrial Fibrillation. J Atr Fibrillation, 12(1), 2195.
• Uriel N, Burkhoff D, Rich JD, Drakos SG, Teuteberg JJ, Imamura T, Rodgers D, Raikhelkar J, Vorovich EE, Selzman CH, Kim G, Sayer G (2019). Impact of Hemodynamic Ramp Test-Guided HVAD Speed and Medication Adjustments on Clinical Outcomes. Circ Heart Fail, 12(4), e006067.
• Yau TM, Pagani FD, Mancini DM, Chang HL, Lala A, Woo YJ, Acker MA, Selzman CH, Soltesz EG, Kern JA, Maltais S, Charbonneau E, Pan S, Marks ME, Moquete EG, OSullivan KL, Taddei-Peters WC, McGowan LK, Green C, Rose EA, Jeffries N, Parides MK, Weisel RD, Miller MA, Hung J, OGara PT, Moskowitz AJ, Gelijns AC, Bagiella E, Milano CA, Cardiothoracic Surgical Trials Network (2019). Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure: A Randomized Clinical Trial. JAMA, 321(12), 1176-1186.
• Watkins WS, Hernandez EJ, Wesolowski S, Bisgrove BW, Sunderland RT, Lin E, Lemmon G, Demarest BL, Miller TA, Bernstein D, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Newburger JW, Seidman CE, Shen Y, Yost HJ, Yandell M, Tristani-Firouzi M (2019). De novo and recessive forms of congenital heart disease have distinct genetic and phenotypic landscapes. Nat Commun, 10(1), 4722.
• Pepin ME, Drakos S, Ha CM, Tristani-Firouzi M, Selzman CH, Fang JC, Wende AR, Wever-Pinzon O (2019). DNA methylation reprograms cardiac metabolic gene expression in end-stage human heart failure. Am J Physiol Heart Circ Physiol, 317(4), H674-H684.
• Serrano MLA, Demarest BL, Tone-Pah-Hote T, Tristani-Firouzi M, Yost HJ (2019). Inhibition of Notch signaling rescues cardiovascular development in Kabuki Syndrome. PLoS Biol, 17(9), e3000087.
• Aromolaran AS (2019). Mechanisms of electrical remodeling in lipotoxic guinea pig heart.Biochem Biophys Res Commun, 519(3), 639-644.
• Martinez-Mateu L, Saiz J, Aromolaran AS (2019). Differential Modulation of IK and ICa,L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria. Front Physiol, 10, 1212.
• Boutjdir M, Aromolaran AS, de Las Fuentes L, Boyington JEA, Arteaga SS, Jobe J, Jeffe DB, Rao DC, Rice TK, Davila-Roman VG (2019). Research Education and Mentoring Program in Cardiovascular Diseases for Under-Represented Junior Faculty From NHLBI SIPID/PRIDE. J Am Coll Cardiol, 73(14), 1861-1865.
• Alí A, Boutjdir M, Aromolaran AS (2019). Cardiolipotoxicity, Inflammation, and Arrhythmias: Role for Interleukin-6 Molecular Mechanisms. Front Physiol, 9, 1866.
• Balderas E, Torres NS, Rosa-Garrido M, Chaudhuri D, Toro L, Stefani E, Olcese R. MitoBK_Ca channel is functionally associated with its regulatory β1 subunit in cardiac mitochondria. J Physiol. 2019 Aug
• Jiang Jingbo*, Hoagland D*, Palatinus JA*, He H*, Iyyathurai J, Jourdan LJ, Bultynck G, Wang Z, Zhang Z, Schey K, Poelzing S, McGowan FX, Gourdie RG, Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia-Reperfusion Injury. J Am Heart Assoc. 2019 Aug 20;
• Tate JD, Pilcher TA, Aras KK, Burton BM, MacLeod RS. Validating Defibrillation Simulation in a Human-Shaped Phantom.Heart rhythm 2019 ;
• Tate JD, Schuler S, Dössel O, MacLeod RS, Oostendorp TF. Correcting Undersampled Cardiac Sources in Equivalent Double Layer Forward Simulations.Functional imaging and modeling of the heart : … International Workshop, FIMH …, proceedings. FIMH 2019 ; 11504 : 147-155;
• Bergquist JA, Good WW, Zenger B, Tate JD, MacLeod RS. GRÖMeR: A Pipeline for Geodesic Refinement of Mesh Registration.Functional imaging and modeling of the heart : … International Workshop, FIMH …, proceedings. FIMH 2019 ; 11504 : 37-45;
• Bergquist JA, Good WW, Zenger B, Tate JD, MacLeod RS. Optimizing the Reconstruction of Cardiac Potentials Using a Novel High Resolution Pericardiac Cage.Computing in cardiology 2019 ; 46;
• Good WW, Gillette KK, Bergquist JA, Zenger B, Tate J, Rupp LC, Anderson D, Plank G, MacLeod RS. Validation of Intramural Wavefront Reconstruction and Estimation of 3D Conduction Velocity. Computing in cardiology 2019 ; 46 ;
• Dogrusoz YS, Bear LR, Bergquist J, Dubois R, Good W, MacLeod RS, Rababah A, Stoks J. Effects of Interpolation on the Inverse Problem of Electrocardiography.Computing in cardiology 2019 ; 46 :
• Angel N, Kholmovski EG, Ghafoori E, Dosdall DJ, MacLeod RS, Ranjan R. Regions of High Dominant Frequency in Chronic Atrial Fibrillation Anchored to Areas of Atrial Fibrosis. Computing in cardiology 2019 ; 46 :
• Zenger B, Bergquist JA, Good WW, Burton BM, Tate JD, MacLeod RS. Experimental Validation of Image-Based Modeling of Torso Surface Potentials During Acute Myocardial Ischemia.Computing in cardiology 2019 ; 46 :
• Zadikany RH, Hong T, Shaw RM. Heart failure: distinguishing failing myocardium from volume overload. Biomark Med. 2019 Jun;13(9):697-700. doi: 10.2217/bmm-2019-0168. Epub 2019 Jun 7. PubMed PMID: 31172804.

2018

• Nikolova AP, Hitzeman TC, Baum R, Caldaruse AM, Agvanian S, Xie Y, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong T, Shaw RM (2018). Association of a Novel Diagnostic Biomarker, the Plasma Cardiac Bridging Integrator 1 Score, With Heart Failure With Preserved Ejection Fraction and Cardiovascular Hospitalization. JAMA Cardiol, 3(12), 1206-1210.
• AA Ahmad, C Hunter, FB Sachse. Sarcoplasmic Reticulum Calcium Leak in Cardiomyocytes: A Contribution of TRPC1 Channels .Biophysical Journal 114 (3), 289a. 2018
• Hong T, Shaw RM. Editorial commentary: Extracellular vesicles in cardiovascular diagnosis and therapy. Trends Cardiovasc Med. 2019 Aug;29(6):324-325. doi: 10.1016/j.tcm.2018.11.007. Epub 2018 Nov 14. PubMed PMID: 30471985; PubMed Central PMCID: PMC6517075.
• Basheer WA, Fu Y, Shimura D, Xiao S, Agvanian S, Hernandez DM, Hitzeman TC, Hong T, Shaw RM (2018). Stress response protein GJA1-20k promotes mitochondrial biogenesis, metabolic quiescence, and cardioprotection against ischemia/reperfusion injury. JCI Insight, 3(20).
• Hickman AW, Lonardo NW, Mone MC, Presson AP, Zhang C, Barton RG, Selzman CH, Drakos SG, Koliopoulou A, McKellar SH (2018). Acid Suppression to Prevent Gastrointestinal Bleeding in Patients With Ventricular Assist Devices. J Surg Res, 234, 96-102.
• Yamashita K, Hu N, Ranjan R, Selzman CH, Dosdall DJ (2018). Clinical Risk Factors for Postoperative Atrial Fibrillation among Patients after Cardiac Surgery. Thorac Cardiovasc Surg, 67(2), 107-116.
• FB Sachse, R Hitchcock, C Huang, AK Kaza. Devices and systems for fluorescence imaging of tissue .US Patent 10,154,785. 2018
• Buffolo M, Pires KM, Ferhat M, Ilkun O, Makaju A, Achenbach A, Bowman F, Atkinson DL, Holland WL, Amri EZ, Chaurasia B, Franklin S, Boudina S (2018). Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. Cell Rep, 29(2), 270-282.e5.
• Warren JS, Tracy CM, Miller MR, Makaju A, Szulik MW, Oka SI, Yuzyuk TN, Cox JE, Kumar A, Lozier BK, Wang L, Llana JG, Sabry AD, Cawley KM, Barton DW, Han YH, Boudina S, Fiehn O, Tucker HO, Zaitsev AV, Franklin S (2018). Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart. Proc Natl Acad Sci U S A, 115(33), E7871-E7880.
• Nikolova AP, Hitzeman TC, Baum R, Caldaruse AM, Agvanian S, Xie Y, Geft DR, Chang DH, Moriguchi JD, Hage A, Azarbal B, Czer LS, Kittleson MM, Patel JK, Wu AHB, Kobashigawa JA, Hamilton M, Hong T*, Shaw RM*. (Corresponding authors) Association of a Novel Diagnostic Biomarker, the Plasma Cardiac Bridging Integrator 1 Score, With Heart Failure With Preserved Ejection Fraction and Cardiovascular Hospitalization. JAMA Cardiol. 2018 Dec 1;3(12):1206-1210. doi: 10.1001/jamacardio.2018.3539. PMCID: PMC6583707.
• Yamashita K, Kholmovski E, Ghafoori E, Kamali R, Kwan E, Lichter J, MacLeod R, Dosdall DJ, Ranjan R (2018). Characterization of edema after cryo and radiofrequency ablations based on serial magnetic resonance imaging. J Cardiovasc Electrophysiol, 30(2), 255-262.
• Lichter J, Kholmovski EG, Coulombe N, Ghafoori E, Kamali R, MacLeod R, Ranjan R (2018). Real-time magnetic resonance imaging-guided cryoablation of the pulmonary veins with acute freeze-zone and chronic lesion assessment. Europace, 21(1), 154-162.
• Kholmovski EG, Silvernagel J, Angel N, Vijayakumar S, Thomas S, Dosdall D, MacLeod R, Marrouche NF, Ranjan R (2018). Acute noncontrast T1-weighted magnetic resonance imaging predicts chronic radiofrequency ablation lesions. J Cardiovasc Electrophysiol, 29(11), 1556-1562.
• Thomas S, Silvernagel J, Angel N, Kholmovski E, Ghafoori E, Hu N, Ashton J, Dosdall DJ, MacLeod R, Ranjan R (2018). Higher contact force during radiofrequency ablation leads to a much larger increase in edema as compared to chronic lesion size. J Cardiovasc Electrophysiol, 29(8), 1143-1149.
• Yamashita K, Quang C, Schroeder JD, DiBella E, Han F, MacLeod R, Dosdall DJ, Ranjan R (2018). Distance between the left atrium and the vertebral body is predictive of esophageal movement in serial MR imaging. J Interv Card Electrophysiol, 52(2), 149-156.
• Ghafoori E, Angel N, Dosdall DJ, MacLeod RS, Ranjan R (2018). Atrial fibrillation observed on surface ECG can be atrial flutter or atrial tachycardia. J Electrocardiol, 51(6S), S67-S71.
• R. Moss, F. B. Sachse, E. G. Moreno-Galindo, R. A. Navarro-Polanco, M. Tristani-Firouzi, G. Seemann. Modeling effects of voltage dependent properties of the cardiac muscarinic receptor on human sinus node function. PLoS Comput Biol 2018 Oct 10;14(10):e1006438. Published, 10/2018.
• M. Streiff, A. A. Ahmad, C. Hunter, and F. B. Sachse. Adult rabbit left ventricle RNAseq, 2018. Gene Expression Omnibus. Series Accession: GSE115605. ID: GSE115605. Published, 08/2018.
• A. Mondal, J. Lackey, M. Saed, F.-Y. Wu, R. Hitchcock, F. Sachse, and A. Kaza. Towards identification of conductive tissue in pediatric heart surgery using fiber optic confocal microscopy. In Proc. 44th Annual Meeting of Western Thoracic Surgical Association, pages 108-9, 2018. Published, 06/2018.
• J. Greiner, A. C. Sankarankutty, G. Seemann, T. Seidel, and F. B. Sachse. Confocal Microscopy-Based Estimation of Parameters for Computational Modeling of Electrical Conduction in the Normal and Infarcted Heart. Front Physiol. 2018 Apr 4;9:239. doi: 10.3389/fphys.2018.00239. Published, 04/2018.
• Cahill BC, Raman S, Stringham JR, McKellar SH, Selzman CH, Liou TG (2018). Longer Life or More Life: Choose One Please. J Surg Res, 237, 126-128.
• Yamashita K, Hu N, Ranjan R, Selzman CH, Dosdall DJ (2018). Clinical Risk Factors for Postoperative Atrial Fibrillation among Patients after Cardiac Surgery. Thorac Cardiovasc Surg, 67(2), 107-116.
• Hickman AW, Lonardo NW, Mone MC, Presson AP, Zhang C, Barton RG, Selzman CH, Drakos SG, Koliopoulou A, McKellar SH (2018). Acid Suppression to Prevent Gastrointestinal Bleeding in Patients With Ventricular Assist Devices. J Surg Res, 234, 96-102.
• Yin MY, Ruckel S, Kfoury AG, McKellar SH, Taleb I, Gilbert EM, Nativi-Nicolau J, Stehlik J, Reid BB, Koliopoulou A, Stoddard GJ, Fang JC, Drakos SG, Selzman CH, Wever-Pinzon O (2018). Novel Model to Predict Gastrointestinal Bleeding During Left Ventricular Assist Device Support. Circ Heart Fail, 11(11), e005267.
• Silverton NA, Patel R, Zimmerman J, Ma J, Stoddard G, Selzman CH, Morrissey CK (2018). Intraoperative Transesophageal Echocardiography and Right Ventricular Failure After Left Ventricular Assist Device Implantation. J Cardiothorac Vasc Anesth, 32(5), 2096-2103.
• Glotzbach JP, Sharma V, Tonna JE, Pettit JC, McKellar SH, Eckhauser AW, Varghese TK Jr, Selzman CH (2018). Value-driven cardiac surgery: Achieving “perfect care” after coronary artery bypass grafting. J Thorac Cardiovasc Surg, 156(4), 1436-1448.e2.
• McKellar SH, Koliopoulou A, Selzman CH (2018). Atrial Fibrillation in Advanced Heart Failure Patients Receiving Left Ventricular Assist Devices. ASAIO J, 64(5), 573-574.
• Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ (2018). The human heart contains distinct macrophage subsets with divergent origins and functions. Nat Med, 24(8), 1234-1245.
• Daud A, Xu D, Revelo MP, Shah Z, Drakos SG, Dranow E, Stoddard G, Kfoury AG, Hammond MEH, Nativi-Nicolau J, Alharethi R, Miller DV, Gilbert EM, Wever-Pinzon O, McKellar SH, Afshar K, Khan F, Fang JC, Selzman CH, Stehlik J (2018). Microvascular Loss and Diastolic Dysfunction in Severe Symptomatic Cardiac Allograft Vasculopathy. Circ Heart Fail, 11(8), e004759.
• Salazar-Fajardo PD, Archiga-Figueroa IA, Lpez-Serrano AL, Rodriguez-Elias JC, Alamilla J, Snchez-Chapula JA, Tristani-Firouzi M, Navarro-Polanco RA, Moreno-Galindo EG (2018). The voltage-sensitive cardiac M2 muscarinic receptor modulates the inward rectification of the G protein-coupled, ACh-gated K+ current. Pflugers Arch, 470(12), 1765-1776.
• Moss R, Sachse FB, Moreno-Galindo EG, Navarro-Polanco RA, Tristani-Firouzi M, Seemann G (2018). Modeling effects of voltage dependent properties of the cardiac muscarinic receptor on human sinus node function. PLoS Comput Biol, 14(10), e1006438.
• Skarsfeldt MA, Bomholtz SH, Lundegaard PR, Lopez-Izquierdo A, Tristani-Firouzi M, Bentzen BH (2018). Atrium-specific ion channels in the zebrafish-A role of IKACh in atrial repolarization. Acta Physiol (Oxf), 223(3), e13049.
• Villatoro-Gmez K, Pacheco-Rojas DO, Moreno-Galindo EG, Navarro-Polanco RA, Tristani-Firouzi M, Gazgalis D, Cui M, Snchez-Chapula JA, Ferrer T (2018). Molecular determinants of Kv7.1/KCNE1 channel inhibition by amitriptyline. Biochem Pharmacol, 152, 264-271.
• Manheimer KB, Patel N, Richter F, Gorham J, Tai AC, Homsy J, Boskovski MT, Parfenov M, Goldmuntz E, Chung WK, Brueckner M, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE, Gelb BD, Sharp AJ (2018). Robust identification of deletions in exome and genome sequence data based on clustering of Mendelian errors. Hum Mutat, 39(6), 870-881.
• Aromolaran AS, Srivastava U, Alí A, Chahine M, Lazaro D, El-Sherif N, Capecchi PL, Laghi-Pasini F, Lazzerini PE, Boutjdir M (2018). Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation. PLoS ONE, 13(12), e0208321.
• Aromolaran AS, Chahine M, Boutjdir M (2018). Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C. Handb Exp Pharmacol, 246, 161-184.
• Kamer KJ, Sancak Y, Fomina Y, Meisel JD, Chaudhuri D, Grabarek Z, Mootha VK. MICU1 imparts the mitochondrial uniporter with the ability to discriminate between Ca²⁺ and Mn²⁺. Proc Natl Acad Sci U S A. 2018 Aug 2;
• Tate J, Stinstra J, Pilcher T, Poursaid A, Jolley MA, Saarel E, Triedman J, MacLeod RS. Measuring defibrillator surface potentials: The validation of a predictive defibrillation computer model.Computers in biology and medicine 2018 ; 102 : 402-410
• Prakosa A, Arevalo HJ, Deng D, Boyle PM, Nikolov PP, Ashikaga H, Blauer JJE, Ghafoori E, Park CJ, Blake RC, Han FT, MacLeod RS, Halperin HR, Callans D. Personalized virtual-heart technology for guiding the ablation of infarct-related ventricular tachycardia.Nature biomedical engineering 2018 ; 2 10 : 732-740
• Burton BM, Aras KK, Good WW, Tate JD, Zenger B, MacLeod RS. A Framework for Image-Based Modeling of Acute Myocardial Ischemia Using Intramurally Recorded Extracellular Potentials.Annals of biomedical engineering 2018 ; 46 9 : 1325-1336
• Tate JD, Zemzemi N, Good WW, van Dam P, Brooks DH, MacLeod RS. Effect of Segmentation Variation on ECG Imaging.Computing in cardiology 2018 ; 45 :
• Dogrusoz YS, Bear LR, Svehlikova J, Coll-Font J, Good W, Dubois R, van Dam E, MacLeod RS. Reduction of Effects of Noise on the Inverse Problem of Electrocardiography with Bayesian Estimation. Computing in cardiology 2018 ; 45 :
• Zenger B, Good WW, Bergquist J, Tate JD, Sharma V, MacLeod RS. Electrocardiographic Comparison of Dobutamine and BRUCE Cardiac Stress Testing With High Resolution Mapping in Experimental Models.Computing in cardiology 2018 ; 45 :
• Good WW, Erem B, Coll-Font J, Zenger B, Horáček BM, Brooks DH, MacLeod RS. Novel Metric Using Laplacian Eigenmaps to Evaluate Ischemic Stress on the Torso Surface. Computing in cardiology 2018 ; 45 :
• Good WW, Erem B, Zenger B, Coll-Font J, Brooks DH, MacLeod RS. Temporal Performance of Laplacian Eigenmaps and 3D Conduction Velocity in Detecting Ischemic Stress. Journal of electrocardiology 2018 ; 51 6S : S116-S120
• Rodenhauser A, Good WW, Zenger B, Tate J, Aras K, Burton B, MacLeod RS. PFEIFER: Preprocessing Framework for Electrograms Intermittently Fiducialized from Experimental Recordings.Journal of open source software 2018 ; 3 21 :

2017

• Epifantseva I, Shaw RM (2017). Intracellular trafficking pathways of Cx43 gap junction channels. Biochim Biophys Acta Biomembr, 1860(1), 40-47.
• Fu Y, Zhang SS, Xiao S, Basheer WA, Baum R, Epifantseva I, Hong T, Shaw RM (2017). Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport. Front Physiol, 8, 905.
• Zhou K, Hong T. Cardiac BIN1 (cBIN1) is a regulator of cardiac contractile function and an emerging biomarker of heart muscle health. Sci China Life Sci. 2017 Mar;60(3):257-263. doi: 10.1007/s11427-016-0249-x. Epub 2016 Nov 23. Review. PubMed PMID: 27888388.
• Basheer WA, Xiao S, Epifantseva I, Fu Y, Kleber AG, Hong T, Shaw RM (2017). GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs. Circ Res, 121(9), 1069-1080.
• Xu B, Fu Y, Liu Y, Agvanian S, Wirka RC, Baum R, Zhou K, Shaw RM, Hong T (2017). The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles. PLoS Biol, 15(8), e2002354.
• Drakos SG, Pagani FD, Lundberg MS, Baldwin JT (2017). Advancing the Science of Myocardial Recovery With Mechanical Circulatory Support: A Working Group of the National, Heart, Lung, and Blood Institute. JACC Basic Transl Sci, 2(3), 335-340.
• Drakos SG, Pagani FD, Lundberg MS, Baldwin JT (2017). Advancing the Science of Myocardial Recovery With Mechanical Circulatory Support: A Working Group of the National, Heart, Lung and Blood Institute. J Card Fail, 23(5), 416-421.
• Tracy C, Warren JS, Szulik M, Wang L, Garcia J, Makaju A, Russell K, Miller M, Franklin S (2017). The Smyd Family of Methyltransferases: Role in Cardiac and Skeletal Muscle Physiology and Pathology. Curr Opin Physiol, 1, 140-152.
• Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME (2017). GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochem J, 474(17), 2951.
• Xu B, Fu Y, Liu Y, Agvanian S, Wirka RC, Baum R, Zhou K, Shaw RM, Hong T. The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles. PLoS Biol. 2017 Aug;15(8):e2002354. doi: 10.1371/journal.pbio.2002354. PMCID: PMC5570487.
• Hong T, Shaw RM. Cardiac T-Tubule Microanatomy and Function. Physiol Rev. 2017 Jan;97(1):227-252. doi: 10.1152/physrev.00037.2015. PMCID: PMC6151489.
• Panitchob N, Li L, Huang J, Ranjan R, Ideker RE, Dosdall DJ (2017). Endocardial Activation Drives Activation Patterns During Long-Duration Ventricular Fibrillation and Defibrillation. Circ Arrhythm Electrophysiol, 10(12).
• Ghafoori E, Kholmovski EG, Thomas S, Silvernagel J, Angel N, Hu N, Dosdall DJ, MacLeod R, Ranjan R (2017). Characterization of Gadolinium Contrast Enhancement of Radiofrequency Ablation Lesions in Predicting Edema and Chronic Lesion Size.LID – e005599 [pii]LID – 10.1161/CIRCEP.117.005599 [doi]. Circ Arrhythm Electrophysiol, 10(11).
• Huang S, Wu L, Huang J, Panitchob N, Hu N, Ranjan R, Dosdall DJ (2017). Restitution characteristics of His bundle and working myocardium in isolated rabbit hearts. PLoS ONE, 12(10), e0186880.
• A. A. Ahmad, M. Streiff, C. Hunter, Q. Hu, and F. B. Sachse. Physiological and pathophysiological role of transient receptor potential canonical channels in cardiac myocytes. Prog Biophys Mol Biol, 130(Pt B):254-63, 2017. Published, 11/2017.
• T. Seidel, A. C. Sankarankutty, and F. B. Sachse. Remodeling of the transverse tubular system after myocardial infarction in rabbit correlates with local fibrosis: A potential role of biomechanics. Prog Biophys Mol Biol, 130(Pt B):302-4, 2017. Published, 11/2017.
• C. Huang, S. Wasmund, R. W. Hitchcock, N. F. Marrouche, and F. B. Sachse. Catheterized fiber-optics confocal microscopy of the beating heart in-situ. Circ Cardiovasc Imaging, 10(10), 2017. Published, 10/2017.
• F. B. Sachse, R. B. Clark, and W. R. Giles. No fuzzy space for intracellular Na⁺ in healthy ventricular myocytes. J Gen Physiol, 149(7):683-7, 2017. Published, 06/2017.
• M. Sanguinetti and F. B. Sachse. Structural determinants and biophysical properties of hERG1 channel gating. In D. P. Zipes and J. Jalife, editors, Cardiac Electrophysiology: From Cell to Bedside, chapter 12. W. B. Saunders Company, 7. edition, 2017. Published, 06/2017.
• A. Mondal, F. B. Sachse, and A. P. Moreno. Modulation of asymmetric flux in heterotypic gap junctions by pore shape, particle size and charge. Front Physiol, 8:206, 2017. Published, 04/2017.
• C. L. Welsh, E. H. Ibrahim, F. B. Sachse, and E. W. Hsu. Noninvasive characterization of myocardial fiber structure using MRI. In E. H. Ibrahim, editor, Heart Mechanics: Magnetic Resonance Imaging – Mathematical Modeling, Pulse Sequences, and Image Analysis, chapter 5, pages 179-246. CRC Press, 2017. Published, 04/2017.
• T. Seidel, S. Navankasattusas, A. Ahmad, N. A. Diakos, W. D. Xu, M. Tristani-Firouzi, M. J. Bonios, I. Taleb, D. Y. Li, C. H. Selzman, S. G. Drakos, and F. B. Sachse. Sheet-like remodeling of the transverse tubular system in human heart failure impairs excitation-contraction coupling and functional recovery by mechanical unloading. Circ, 135(17):1632-45, 2017. Published, 04/2017.
• R. B. Clark, T. Schmidt, F. B. Sachse, D. Boyle, G. Firestein, and W. R. Giles. Cellular electrophysiological principles that modulate secretion from synovial fibroblasts. J Physiol, 595(3):635-45, 2017. Published, 02/2017.
• A. A. Ahmad, C. Hunter, Q. Hu, and F. B. Sachse. Functional role of TRPC1 channels in neonatal cardiomyocytes. In Biophys J (Annual Meeting Abstracts), volume 112, page 97a, 2017. Published, 02/2017.
• A. Mondal, D. A. Appadurai, N. W. Akoum, F. B. Sachse, and A. P. Moreno. Computational simulations of asymmetric fluxes of large molecules through gap junction channel pores. J Theor Biol, 412:61-73. Published, 01/2017.
• Bonios MJ, Koliopoulou A, Wever-Pinzon O, Taleb I, Stehlik J, Xu W, Wever-Pinzon J, Catino A, Kfoury AG, Horne BD, Nativi-Nicolau J, Adamopoulos SN, Fang JC, Selzman CH, Bax JJ, Drakos SG (2017). Cardiac Rotational Mechanics As a Predictor of Myocardial Recovery in Heart Failure Patients Undergoing Chronic Mechanical Circulatory Support: A Pilot Study. Circ Cardiovasc Imaging, 11(4), e007117.
• Zuiga Cisneros J, Stehlik J, Selzman CH, Drakos SG, McKellar SH, Wever-Pinzon O (2017). Outcomes in Patients With Hypertrophic Cardiomyopathy Awaiting Heart Transplantation. Circ Heart Fail, 11(3), e004378.
• Saarel EV, Granger S, Kaltman JR, Minich LL, Tristani-Firouzi M, Kim JJ, Ash K, Tsao SS, Berul CI, Stephenson EA, Gamboa DG, Trachtenberg F, Fischbach P, Vetter VL, Czosek RJ, Johnson TR, Salerno JC, Cain NB, Pass RH, Zeltser I, Silver ES, Kovach JR, Alexander ME, Pediatric Heart Network Investigators (2017). Electrocardiograms in Healthy North American Children in the Digital Age. Circ Arrhythm Electrophysiol, 11(7), e005808.
• Jin SC, Homsy J, Zaidi S, Lu Q, Morton S, DePalma SR, Zeng X, Qi H, Chang W, Sierant MC, Hung WC, Haider S, Zhang J, Knight J, Bjornson RD, Castaldi C, Tikhonoa IR, Bilguvar K, Mane SM, Sanders SJ, Mital S, Russell MW, Gaynor JW, Deanfield J, Giardini A, Porter GA Jr, Srivastava D, Lo CW, Shen Y, Watkins WS, Yandell M, Yost HJ, Tristani-Firouzi M, Newburger JW, Roberts AE, Kim R, Zhao H, Kaltman JR, Goldmuntz E, Chung WK, Seidman JG, Gelb BD, Seidman CE, Lifton RP, Brueckner M (2017). Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands. Nat Genet, 49(11), 1593-1601.
• Ramroop R, Manase G, Lu D, Manase D, Chen S, Kim R, Lee T, Mahle WT, McHugh K, Mitchell M, Tristani-Firouzi M, Wechsler SB, Wilder NS, Zak V, Lafreniere-Roula M, Newburger JW, Gaynor JW, Russell MW, Mital S (2017). Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial. J Thorac Cardiovasc Surg, 154(5), 1703-1710.e3.
• Shankaran SS, Dahlem TJ, Bisgrove BW, Yost HJ, Tristani-Firouzi M (2017). CRISPR/Cas9-Directed Gene Editing for the Generation of Loss-of-Function Mutants in High-Throughput Zebrafish F0 Screens. Curr Protoc Mol Biol, 119, 31.9.1-31.9.22.
• Seidel T, Navankasattusas S, Ahmad A, Diakos NA, Xu WD, Tristani-Firouzi M, Bonios MJ, Taleb I, Li DY, Selzman CH, Drakos SG, Sachse FB (2017). Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading. Circulation, 135(17), 1632-1645.
• Mitzelfelt KA, McDermott-Roe C, Grzybowski MN, Marquez M, Kuo CT, Riedel M, Lai S, Choi MJ, Kolander KD, Helbling D, Dimmock DP, Battle MA, Jou CJ, Tristani-Firouzi M, Verbsky JW, Benjamin IJ, Geurts AM (2017). Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection. Stem Cell Reports, 8(3), 491-499.
• Jou CJ, Arrington CB, Barnett S, Shen J, Cho S, Sheng X, McCullagh PC, Bowles NE, Pribble CM, Saarel EV, Pilcher TA, Etheridge SP, Tristani-Firouzi M (2017). A Functional Assay for Sick Sinus Syndrome Genetic Variants. Cell Physiol Biochem, 42(5), 2021-2029.
• Lazzerini PE, Laghi-Pasini F, Bertolozzi I, Morozzi G, Lorenzini S, Simpatico A, Selvi E, Bacarelli MR, Finizola F, Vanni F, Lazaro D, Aromolaran A, El Sherif N, Boutjdir M, Capecchi PL (2017). Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes. Heart, 103(22), 1821-1829.
• Aromolaran AS, Boutjdir M (2017). Cardiac Ion Channel Regulation in Obesity and the Metabolic Syndrome: Relevance to Long QT Syndrome and Atrial Fibrillation. Front Physiol, 8, 431.
• Srivastava U, Aromolaran AS, Fabris F, Lazaro D, Kassotis J, Qu Y, Boutjdir M (2017). Novel function of α1D L-type calcium channel in the atria. Biochem Biophys Res Commun, 482(4), 771-776.
• Sommakia S, Houlihan PR, Deane SS, Simcox JA, Torres NS, Jeong MY, Winge DR, Villanueva CJ, Chaudhuri D. Mitochondrial cardiomyopathies feature increased uptake and diminished efflux of mitochondrial calcium. J Mol Cell Cardiol. 2017 Dec;
• Abiria SA, Krapivinsky G, Sah R, Santa-Cruz AG, Chaudhuri D, Zhang J, Adstamongkonkul P, DeCaen PG, Clapham DE. TRPM7 senses oxidative stress to release Zn²⁺ from unique intracellular vesicles. Proc Natl Acad Sci U S A. 2017 Jul 25;
• Fidler TP, Campbell RA, Funari T, Dunne N, Balderas Angeles E, Middleton EA, Chaudhuri D, Weyrich AS, Abel ED. Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function. Cell Rep. 2017 Jul 25;
• Ghimire S, Dhamala J, Coll-Font J, Tate JD, Guillem MS, Brooks DH, MacLeod RS, Wang L. Overcoming Barriers to Quantification and Comparison of Electrocardiographic Imaging Methods: A Community-Based Approach.Computing in cardiology 2017 ; 44 :
• Good WW, Erem B, Coll-Font J, Brooks DH, MacLeod RS. Detecting Ischemic Stress to the Myocardium Using Laplacian Eigenmaps and Changes to Conduction Velocity.Computing in cardiology 2017 ; 44 :

2016

• Hong T, Shaw RM (2016). Cardiac T-Tubule Microanatomy and Function. Physiol Rev, 97(1), 227-252.
• Fu Y, Hong T. BIN1 regulates dynamic t-tubule membrane. Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1839-47. doi: 10.1016/j.bbamcr.2015.11.004. Epub 2015 Nov 11. Review. PubMed PMID: 26578114; PubMed Central PMCID: PMC4864156.
• Levitan BM, Manning JR, Withers CN, Smith JD, Shaw RM, Andres DA, Sorrell VL, Satin J (2016). Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart. J Cardiovasc Transl Res, 9(5-6), 432-444.
• Wever-Pinzon J, Selzman CH, Stoddard G, Wever-Pinzon O, Catino A, Kfoury AG, Diakos NA, Reid BB, McKellar S, Bonios M, Koliopoulou A, Budge D, Kelkhoff A, Stehlik J, Fang JC, Drakos SG (2016). Impact of Ischemic Heart Failure Etiology on Cardiac Recovery During Mechanical Unloading. J Am Coll Cardiol, 68(16), 1741-1752.
• Wever-Pinzon O, Drakos SG, McKellar SH, Horne BD, Caine WT, Kfoury AG, Li DY, Fang JC, Stehlik J, Selzman CH (2016). Cardiac Recovery During Long-Term Left Ventricular Assist Device Support. J Am Coll Cardiol, 68(14), 1540-53.
• Healy AH, Stehlik J, Edwards LB, McKellar SH, Drakos SG, Selzman CH (2016). Predictors of 30-day post-transplant mortality in patients bridged to transplantation with continuous-flow left ventricular assist devices–An analysis of the International Society for Heart and Lung Transplantation Transplant Registry. J Heart Lung Transplant, 35(1), 34-39.
• Diakos NA, Navankasattusas S, Abel ED, Rutter J, McCreath L, Ferrin P, McKellar SH, Richardson R, Deberardinis R, Kfoury AG, Selzman CH, Stehlik J, Fang JC, Li DY, Drakos SG (2016). Evidence of glycolysis upregulation and pyruvate mitochondrial oxidation mismatch during mechanical unloading of the failing human heart: implications for cardiac reloading and conditioning. JACC Basic Transl Sci.
• Drakos SG, Mehra MR (2016). Clinical myocardial recovery during long-term mechanical support in advanced heart failure: insights into moving the field forward. J Heart Lung Transplant, 35(4), 413-20
• Franklin S, Kimball T, Rasmussen TL, Rosa-Garrido M, Chen H, Tran T, Miller MR, Gray R, Jiang S, Ren S, Wang Y, Tucker HO, Vondriska TM (2016). The chromatin-binding protein Smyd1 restricts adult mammalian heart growth. Am J Physiol Heart Circ Physiol, 311(5), H1234-H1247.
• Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME (2016). GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochem J, 473(19), 3355-69.
• Monte E, Rosa-Garrido M, Karbassi E, Chen H, Lopez R, Rau CD, Wang J, Nelson SF, Wu Y, Stefani E, Lusis AJ, Wang Y, Kurdistani SK, Franklin S, Vondriska TM (2016). Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. J Biol Chem, 291(30), 15428-46.
• Fu Y, Shaw SA, Naami R, Vuong CL, Basheer WA, Guo X, Hong T. Isoproterenol Promotes Rapid Ryanodine Receptor Movement to Bridging Integrator 1 (BIN1)-Organized Dyads. Circulation. 2016 Jan 26;133(4):388-97. doi: 10.1161/CIRCULATIONAHA.115.018535. PMCID: PMC4729615.
• Polejaeva IA, Ranjan R, Davies CJ, Regouski M, Hall J, Olsen AL, Meng Q, Rutigliano HM, Dosdall DJ, Angel NA, Sachse FB, Seidel T, Thomas AJ, Stott R, Panter KE, Lee PM, Van Wettere AJ, Stevens JR, Wang Z, MacLeod RS, Marrouche NF, White KL (2016). Increased Susceptibility to Atrial Fibrillation Secondary to Atrial Fibrosis in Transgenic Goats Expressing Transforming Growth Factor-β1. J Cardiovasc Electrophysiol, 27(10), 1220-1229.
• Kholmovski EG, Coulombe N, Silvernagel J, Angel N, Parker D, Macleod R, Marrouche N, Ranjan R (2016). Real-Time MRI-Guided Cardiac Cryo-Ablation: A Feasibility Study. J Cardiovasc Electrophysiol, 27(5), 602-8.
• W. Wu, A. Gardener, F. B. Sachse, and M. C. Sanguinetti. Ginsenoside Rg3, a gating modifier of EAG family K+ channels. Mol Pharmacol, 90(4):469-82, 2016. Published, 10/2016.
• O. M. Abdullah, T. Seidel, M. Dahl, A. D. Gomez, G. Yiep, J. Cortino, F. B. Sachse, K. H. Albertine, and E. W. Hsu. Diffusion tensor imaging and histology of developing hearts. NMR Biomed, 29(10):1338-49, 2016. Published, 10/2016.
• Romero D, Camara O, Sachse F, Sebastian R. Analysis of Microstructure of the Cardiac Conduction System Based on Three-Dimensional Confocal Microscopy. PLoS One. 2016 Oct 7;11(10):e0164093. 2016. Published, 10/2016.
• I. A. Polejaeva, R. Ranjan, C. J. Davies, M. Regouski, J. Hall, A. L. Olsen, Q. Meng, H. M. Rutigliano, D. J. Dosdall, N. A. Angel, F. B. Sachse, T. Seidel, A. J. Thomas, R. Stott, K. E. Panter, P. M. Lee, A. J. Van Wettere, J. R. Stevens, Z. Wang, R. S. Macleod, N. F. Marrouche, and K. L. White. Increased susceptibility to atrial fibrillation secondary to atrial fibrosis in transgenic goats expressing transforming growth factor-β1. J. Cardiovasc Electrophysiol, 27(10):1220-9, 2016. Published, 10/2016.
• J. Lichter, H. Li, and F. B. Sachse. Measurement of strain in cardiac myocytes at micrometer scale based on rapid scanning confocal microscopy and non-rigid image registration. Ann Biomed Eng, 44(10):3020-31, 2016. Published, 10/2016.
• Seidel T, Edelmann JC, Sachse FB. Analyzing Remodeling of Cardiac Tissue: A Comprehensive Approach Based on Confocal Microscopy and 3D Reconstructions. Ann Biomed Eng. 44(5):1436-48, 2016. Published, 05/2016.
• Huang C, Sachse FB, Hitchcock RW, Kaza AK. Sensitivity and Specificity of Cardiac Tissue Discrimination Using Fiber-Optics Confocal Microscopy. PLoS One. 11(1):e0147667, 2016. Published, 01/2016.
• Moreno-Galindo EG, Sanchez-Chapula JA, Tristani-Firouzi M, Navarro-Polanco RA (2016). Pharmacological Conversion of a Cardiac Inward Rectifier into an Outward Rectifier Potassium Channel. Mol Pharmacol, 90(3), 334-40.
• Moreno-Galindo EG, Alamilla J, Sanchez-Chapula JA, Tristani-Firouzi M, Navarro-Polanco RA (2016). The agonist-specific voltage dependence of M2 muscarinic receptors modulates the deactivation of the acetylcholine-gated K(+) current (I KACh). Pflugers Arch, 468(7), 1207-1214.
• Aromolaran AS, Colecraft HM, Boutjdir M (2016). High-fat diet-dependent modulation of the delayed rectifier K(+) current in adult guinea pig atrial myocytes. Biochem Biophys Res Commun, 474(3), 554-559.
• Puckerin A, Aromolaran KA, Chang DD, Zukin RS, Colecraft HM, Boutjdir M, Aromolaran AS (2016). hERG 1a LQT2 C-terminus truncation mutants display hERG 1b-dependent dominant negative mechanisms. Heart Rhythm, 13(5), 1121-1130.
• Chaudhuri D, Artiga DJ, Abiria SA, Clapham DE. Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition. Proc Natl Acad Sci U S A. 2016 Mar 29;
• Basheer W, Shaw R (2015). The “tail” of Connexin43: An unexpected journey from alternative translation to trafficking. Biochim Biophys Acta, 1863(7 Pt B), 1848-56.
• Basheer WA, Shaw RM (2015). Connexin 43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium. Circ Arrhythm Electrophysiol, 9(6), e001357.
• Kfoury AG, Miller DV, Snow GL, Afshar K, Stehlik J, Drakos SG, Budge D, Fang JC, Revelo MP, Alharethi RA, Gilbert EM, Caine WT, McKellar S, Molina KM, Hammond MEH (2015). Mixed cellular and antibody-mediated rejection in heart transplantation: In-depth pathologic and clinical observations. J Heart Lung Transplant, 35(3), 335-341.
• Witman MA, Garten RS, Gifford JR, Groot HJ, Trinity JD, Stehlik J, Nativi JN, Selzman CH, Drakos SG, Richardson RS (2015). Further Peripheral Vascular Dysfunction in Heart Failure Patients With a Continuous-Flow Left Ventricular Assist Device: The Role of Pulsatility. JACC Heart Fail, 3(9), 703-11.
• Wachter SB, McCandless SP, Gilbert EM, Stoddard GJ, Kfoury AG, Reid BB, McKellar SH, Nativi-Nicolau J, Saidi A, Barney J, McCreath L, Koliopoulou A, Wright SE, Fang JC, Stehlik J, Selzman CH, Drakos SG (2015). Elevated resting heart rate in heart transplant recipients: innocent bystander or adverse prognostic indicator? Clin Transplant, 29(9), 829-34.
• Hong K, Jeong EK, Wall TS, Drakos SG, Kim D (2015). Wideband arrhythmia-Insensitive-rapid (AIR) pulse sequence for cardiac T1 mapping without image artifacts induced by an implantable-cardioverter-defibrillator. Magn Reson Med, 74(2), 336-45.
• Healy AH, Koliopoulou A, Drakos SG, McKellar SH, Stehlik J, Selzman CH (2015). Patient-controlled conditioning for left ventricular assist device-induced myocardial recovery. Ann Thorac Surg, 99(5), 1794-6.
• Selzman CH, Madden JL, Healy AH, McKellar SH, Koliopoulou A, Stehlik J, Drakos SG (2015). Bridge to removal: a paradigm shift for left ventricular assist device therapy. Ann Thorac Surg, 99(1), 360-7.
• Angel N, Li LI, Macleod RS, Marrouche N, Ranjan R, Dosdall DJ (2015). Diverse Fibrosis Architecture and Premature Stimulation Facilitate Initiation of Reentrant Activity Following Chronic Atrial Fibrillation. J Cardiovasc Electrophysiol, 26(12), 1352-60.
• Shibayama J, Yuzyuk TN, Cox J, Makaju A, Miller M, Lichter J, Li H, Leavy JD, Franklin S, Zaitsev AV (2015). Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study. PLoS ONE, 10(3), e0118974.
• Plimpton RL, Cullar J, Lai CW, Aoba T, Makaju A, Franklin S, Mathis AD, Prince JT, Carrascosa JL, Valpuesta JM, Willardson BM (2015). Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly. Proc Natl Acad Sci U S A, 112(8), 2413-8.
• Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnczky G, Kwon O, Chen JN (2015). Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. eLife, 4.
• Angel N, Li LI, Macleod RS, Marrouche N, Ranjan R, Dosdall DJ (2015). Diverse Fibrosis Architecture and Premature Stimulation Facilitate Initiation of Reentrant Activity Following Chronic Atrial Fibrillation. J Cardiovasc Electrophysiol, 26(12), 1352-60.
• Parmar BR, Jarrett TR, Kholmovski EG, Hu N, Parker D, MacLeod RS, Marrouche NF, Ranjan R (2015). Poor scar formation after ablation is associated with atrial fibrillation recurrence. J Interv Card Electrophysiol, 44(3), 247-56.
• Li H, Lichter JG, Seidel T, Tomaselli GF, Bridge JH, Sachse FB. Circ Heart Fail. Cardiac Resynchronization Therapy Reduces Subcellular Heterogeneity of Ryanodine Receptors, T-Tubules, and Ca2+ Sparks Produced by Dyssynchronous Heart Failure. Circ Heart Fail, 8:1105-14, 2015. Published, 11/2015.
• Diakos NA, Selzman CH, Stehlik J, Sachse FB, Kfoury AG, Koliopoulou A, McKellar S, Fang JC, Li DY, Drakos SG.Reply: does size matter? In search of a physiological definition of myocardial atrophy. J Am Coll Cardiol. 65(19):2156-7, 2015. Published, 05/2015.
• Wemhöner K, Friedrich C, Stallmeyer B, Coffey AJ, Grace A, Zumhagen S, Seebohm G, Ortiz-Bonnin B, Rinné S, Sachse FB, Schulze-Bahr E, Decher N. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome. J Mol Cell Cardiol, 80C:186-95, 2015. Published, 03/2015.
• Bowles NE, Jou CJ, Arrington CB, Kennedy BJ, Earl A, Matsunami N, Meyers LL, Etheridge SP, Saarel EV, Bleyl SB, Yost HJ, Yandell M, Leppert MF, Tristani-Firouzi M, Gruber PJ, Baylor Hopkins Centers for Mendelian Genomics (2015). Exome analysis of a family with Wolff-Parkinson-White syndrome identifies a novel disease locus. Am J Med Genet A, 167A(12), 2975-84.
• Tristani-Firouzi M (2015). Revisiting the challenges of universal screening for long QT syndrome. J Electrocardiol, 48(6), 1053-7.
• Palatinus, Joseph A, Robert G. Gourdie, Diabetes Increases Cryoinjury Size with Associated Effects on Cx43 Gap Junction Function and Phosphorylation in the Mouse Heart. J Diabetes research. 2016. Epub 2015 Dec 14.
• Coll-Font J, Dhamala J, Potyagaylo D, Schulze WH, Tate JD, Guillem MS, van Dam P, Dossel O, Brooks DH, Macleod RS. The Consortium for Electrocardiographic Imaging.Comput Cardiol 2016 Sep ; 43 : 325-328
• Good WW, Erem B, Coll-Font J, Brooks DH, MacLeod RS. Novel Biomarker for Evaluating Ischemic Stress Using an Electrogram Derived Phase Space. Comput Cardiol 2016 Sep ; 43 : 1057-1060
• Erem B, Martinez Orellana R, Hyde DE, Peters JM, Duffy FH, Stovicek P, Warfield SK, MacLeod RS, Tadmor G, Brooks DH. Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals. Phys Rev E 2016 Apr ; 93 4 : 042218
• Polejaeva IA, Ranjan R, Davies CJ, Regouski M, Hall J, Olsen AL, Meng Q, Rutigliano HM, Dosdall DJ, Angel NA, Sachse FB, Seidel T, Thomas AJ, Stott R,. Increased Susceptibility to Atrial Fibrillation Secondary to Atrial Fibrosis in Transgenic Goats Expressing Transforming Growth Factor-β1.Journal of cardiovascular electrophysiology 2016 ; 27 10 : 1220-1229
• Parmar BR, Jarrett TR, Kholmovski EG, Hu N, Parker D, MacLeod RS, Marrouche NF, Ranjan R. Poor scar formation after ablation is associated with atrial fibrillation recurrence.J Interv Card Electrophysiol 2015 Dec ; 44 3 : 247-56
• Angel N, Li LI, Macleod RS, Marrouche N, Ranjan R, Dosdall DJ. Diverse Fibrosis Architecture and Premature Stimulation Facilitate Initiation of Reentrant Activity Following Chronic Atrial Fibrillation. J Cardiovasc Electrophysiol 2015 Dec ; 26 12 : 1352-60

2015

• Basheer W, Shaw R (2015). The “tail” of Connexin43: An unexpected journey from alternative translation to trafficking. Biochim Biophys Acta, 1863(7 Pt B), 1848-56.
• Fu Y, Xiao S, Hong T, Shaw RM. Cytoskeleton regulation of ion channels. Circulation. 2015 Feb 24;131(8):689-91. doi: 10.1161/CIRCULATIONAHA.115.015216. Epub 2015 Jan 28. PubMed PMID: 25632042; PubMed Central PMCID: PMC4456191.
• Basheer WA, Shaw RM (2015). Connexin 43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium. Circ Arrhythm Electrophysiol, 9(6), e001357.
• Kfoury AG, Miller DV, Snow GL, Afshar K, Stehlik J, Drakos SG, Budge D, Fang JC, Revelo MP, Alharethi RA, Gilbert EM, Caine WT, McKellar S, Molina KM, Hammond MEH (2015). Mixed cellular and antibody-mediated rejection in heart transplantation: In-depth pathologic and clinical observations. J Heart Lung Transplant, 35(3), 335-341.
• Witman MA, Garten RS, Gifford JR, Groot HJ, Trinity JD, Stehlik J, Nativi JN, Selzman CH, Drakos SG, Richardson RS (2015). Further Peripheral Vascular Dysfunction in Heart Failure Patients With a Continuous-Flow Left Ventricular Assist Device: The Role of Pulsatility. JACC Heart Fail, 3(9), 703-11.
• Wachter SB, McCandless SP, Gilbert EM, Stoddard GJ, Kfoury AG, Reid BB, McKellar SH, Nativi-Nicolau J, Saidi A, Barney J, McCreath L, Koliopoulou A, Wright SE, Fang JC, Stehlik J, Selzman CH, Drakos SG (2015). Elevated resting heart rate in heart transplant recipients: innocent bystander or adverse prognostic indicator? Clin Transplant, 29(9), 829-34.
• Hong K, Jeong EK, Wall TS, Drakos SG, Kim D (2015). Wideband arrhythmia-Insensitive-rapid (AIR) pulse sequence for cardiac T1 mapping without image artifacts induced by an implantable-cardioverter-defibrillator. Magn Reson Med, 74(2), 336-45.
• Healy AH, Koliopoulou A, Drakos SG, McKellar SH, Stehlik J, Selzman CH (2015). Patient-controlled conditioning for left ventricular assist device-induced myocardial recovery. Ann Thorac Surg, 99(5), 1794-6.
• Selzman CH, Madden JL, Healy AH, McKellar SH, Koliopoulou A, Stehlik J, Drakos SG (2015). Bridge to removal: a paradigm shift for left ventricular assist device therapy. Ann Thorac Surg, 99(1), 360-7.
• Angel N, Li LI, Macleod RS, Marrouche N, Ranjan R, Dosdall DJ (2015). Diverse Fibrosis Architecture and Premature Stimulation Facilitate Initiation of Reentrant Activity Following Chronic Atrial Fibrillation. J Cardiovasc Electrophysiol, 26(12), 1352-60.
• Shibayama J, Yuzyuk TN, Cox J, Makaju A, Miller M, Lichter J, Li H, Leavy JD, Franklin S, Zaitsev AV (2015). Metabolic remodeling in moderate synchronous versus dyssynchronous pacing-induced heart failure: integrated metabolomics and proteomics study. PLoS ONE, 10(3), e0118974.
• Plimpton RL, Cullar J, Lai CW, Aoba T, Makaju A, Franklin S, Mathis AD, Prince JT, Carrascosa JL, Valpuesta JM, Willardson BM (2015). Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly. Proc Natl Acad Sci U S A, 112(8), 2413-8.
• Shimizu H, Schredelseker J, Huang J, Lu K, Naghdi S, Lu F, Franklin S, Fiji HD, Wang K, Zhu H, Tian C, Lin B, Nakano H, Ehrlich A, Nakai J, Stieg AZ, Gimzewski JK, Nakano A, Goldhaber JI, Vondriska TM, Hajnczky G, Kwon O, Chen JN (2015). Mitochondrial Ca(2+) uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity. eLife, 4.
• Angel N, Li LI, Macleod RS, Marrouche N, Ranjan R, Dosdall DJ (2015). Diverse Fibrosis Architecture and Premature Stimulation Facilitate Initiation of Reentrant Activity Following Chronic Atrial Fibrillation. J Cardiovasc Electrophysiol, 26(12), 1352-60.
• Parmar BR, Jarrett TR, Kholmovski EG, Hu N, Parker D, MacLeod RS, Marrouche NF, Ranjan R (2015). Poor scar formation after ablation is associated with atrial fibrillation recurrence. J Interv Card Electrophysiol, 44(3), 247-56.
• Li H, Lichter JG, Seidel T, Tomaselli GF, Bridge JH, Sachse FB. Circ Heart Fail. Cardiac Resynchronization Therapy Reduces Subcellular Heterogeneity of Ryanodine Receptors, T-Tubules, and Ca2+ Sparks Produced by Dyssynchronous Heart Failure. Circ Heart Fail, 8:1105-14, 2015. Published, 11/2015.
• Diakos NA, Selzman CH, Stehlik J, Sachse FB, Kfoury AG, Koliopoulou A, McKellar S, Fang JC, Li DY, Drakos SG.Reply: does size matter? In search of a physiological definition of myocardial atrophy. J Am Coll Cardiol. 65(19):2156-7, 2015. Published, 05/2015.
• Wemhöner K, Friedrich C, Stallmeyer B, Coffey AJ, Grace A, Zumhagen S, Seebohm G, Ortiz-Bonnin B, Rinné S, Sachse FB, Schulze-Bahr E, Decher N. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome. J Mol Cell Cardiol, 80C:186-95, 2015. Published, 03/2015.
• Bowles NE, Jou CJ, Arrington CB, Kennedy BJ, Earl A, Matsunami N, Meyers LL, Etheridge SP, Saarel EV, Bleyl SB, Yost HJ, Yandell M, Leppert MF, Tristani-Firouzi M, Gruber PJ, Baylor Hopkins Centers for Mendelian Genomics (2015). Exome analysis of a family with Wolff-Parkinson-White syndrome identifies a novel disease locus. Am J Med Genet A, 167A(12), 2975-84.
• Tristani-Firouzi M (2015). Revisiting the challenges of universal screening for long QT syndrome. J Electrocardiol, 48(6), 1053-7.
• Gao Y, Zhu L, Cates J, MacLeod RS, Bouix S, Tannenbaum A. A Kalman Filtering Perspective for Multiatlas Segmentation.SIAM J Imaging Sci 2015 ; 8 2 : 1007-1029
• McDowell KS, Zahid S, Vadakkumpadan F, Blauer J, MacLeod RS, Virtual electrophysiological study of atrial fibrillation in fibrotic remodeling.Trayanova NA. PLoS One 2015 ; 10 2 : e0117110

2014

• Xiao S, Shaw RM (2014). Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention. Trends Cardiovasc Med, 25(5), 379-89.
• Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, Izu LT, Maier LS, Maltsev VA, Marionneau C, Mohler PJ, Rajamani S, Rasmusson RL, Sobie EA, Clancy CE, Bers DM (2014). Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol, 593(6), 1347-60.
• Shaw RM (2014). Desmosomal hotspots, microtubule delivery, and cardiac arrhythmogenesis. Dev Cell, 31(2), 139-40.
• Smyth JW, Zhang SS, Sanchez JM, Lamouille S, Vogan JM, Hesketh GG, Hong T, Tomaselli GF, Shaw RM (2014). A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia. Traffic, 15(6), 684-99.
• Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbn E, Jan LY, Shaw RM (2014). Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med, 20(6), 624-32.
• Zhang SS, Hong S, Klber AG, Lee LP, Shaw RM (2014). A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders. FEBS Lett, 588(8), 1439-45.
• Schumacher-Bass SM, Vesely ED, Zhang L, Ryland KE, McEwen DP, Chan PJ, Frasier CR, McIntyre JC, Shaw RM, Martens JR (2014). Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes. Circ Res, 114(6), 982-92.
• Zhang SS, Shaw RM (2014). Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization. Cell Commun Adhes, 21(1), 43-54.
• Abdullah OM, Drakos SG, Diakos NA, Wever-Pinzon O, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Brunisholz K, Verma DR, Myrick C, Sachse FB, Li DY, Hsu EW (2014). Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation. NMR Biomed, 27(11), 1378-86.
• Diakos NA, Selzman CH, Sachse FB, Stehlik J, Kfoury AG, Wever-Pinzon O, Catino A, Alharethi R, Reid BB, Miller DV, Salama M, Zaitsev AV, Shibayama J, Li H, Fang JC, Li DY, Drakos SG (2014). Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery. J Am Coll Cardiol, 64(15), 1602-12.
• Madden JL, Drakos SG, Stehlik J, McKellar SH, Rondina MT, Weyrich AS, Selzman CH (2014). Baseline red blood cell osmotic fragility does not predict the degree of post-LVAD hemolysis. ASAIO J, 60(5), 524-8.
• Park SY, Gifford JR, Andtbacka RH, Trinity JD, Hyngstrom JR, Garten RS, Diakos NA, Ives SJ, Dela F, Larsen S, Drakos S, Richardson RS (2014). Cardiac, skeletal, and smooth muscle mitochondrial respiration: are all mitochondria created equal? Am J Physiol Heart Circ Physiol, 307(3), H346-52.
• Wever-Pinzon O, Romero J, Kelesidis I, Wever-Pinzon J, Manrique C, Budge D, Drakos SG, Pia IL, Kfoury AG, Garcia MJ, Stehlik J (2014). Coronary computed tomography angiography for the detection of cardiac allograft vasculopathy: a meta-analysis of prospective trials. J Am Coll Cardiol, 63(19), 1992-2004.
• Wozniak CJ, Stehlik J, Baird BC, McKellar SH, Song HK, Drakos SG, Selzman CH (2014). Ventricular assist devices or inotropic agents in status 1A patients? Survival analysis of the United Network of Organ Sharing database. Ann Thorac Surg, 97(4), 1364-71; discussion 1371-2.
• Omar Wever-Pinzon, Jorge Romero, Iosif Kelesidis, James Wever-Pinzon, Carlos Manrique, Deborah Budge, Drakos SG, Ileana Pina, Abdallah G Kfoury, Mario J Garcia, Josef Stehlik (3/2014). Coronary Computed Tomography Angiography for the Detection of Cardiac Allograft Vasculopathy: A Meta-Analysis of Prospective Trials ONLINE FIRST. J Am Coll Cardiol.
• Frech T, De Domenico I, Murtaugh MA, Revelo MP, Li DY, Sawitzke AD, Drakos SG (2014). Autophagy is a key feature in the pathogenesis of scytemic sclerosis. Rheumatol Int, 34(3), 435-439.
• Huang J, Dosdall DJ, Cheng KA, Li L, Rogers JM, Ideker RE (2014). The importance of Purkinje activation in long duration ventricular fibrillation. J Am Heart Assoc, 3(1), e000495.
• Kumar P P, Emechebe U, Smith R, Franklin S, Moore B, Yandell M, Lessnick SL, Moon AM (2014). Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. eLife, 3.
• Kumar P P, Franklin S, Emechebe U, Hu H, Moore B, Lehman C, Yandell M, Moon AM (2014). TBX3 regulates splicing in vivo: a novel molecular mechanism for Ulnar-mammary syndrome. PLoS Genet, 10(3), e1004247.
• Hong T, Yang H, Zhang SS, Cho HC, Kalashnikova M, Sun B, Zhang H, Bhargava A, Grabe M, Olgin J, Gorelik J, Marbán E, Jan LY, Shaw RM. Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia. Nat Med. 2014 Jun;20(6):624-32. doi: 10.1038/nm.3543. PMCID: PMC4048325.
• K. Wemhoener, C. Friedrich, B. Stallmeyer, A. J. Coffey, A. Grace, S. Zumhagen, G. Seebohm, B. Ortiz-Bonnin, S. Rinne, F. B. Sachse, E. Schulze-Bahr, and N. Decher. Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome. J Mol Cell Cardiol, 2014. Published, 12/2014.
• C. Huang, A. K. Kaza, R. W. Hitchcock, and F. B. Sachse. Identification of nodal tissue in the living heart using rapid scanning fiber-optics confocal microscopy and extracellular fluorophores. Circ Cardiovasc Imaging, 6(5):739-46, 2013. Published, 11/2014.
• N. Diakos, C. Selzman, F. B. Sachse, O. Wever-Pinzon, A. Catino, A. Kfoury, J. Stehlik, R. Alharethi, B. Reid, D. Miller, M. Salama, A. Zaitsev, J. Shibayama, H. Li, J. Fang, D. Li, and S. Drakos. Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for ventricular assist device-induced cardiac recovery. J Am Coll Cardiol, 64(15):1602-12, 2014. Published, 11/2014.
• O. M. Abdullah, S. G. Drakos, N. A. Diakos, O. Wever-Pinzon, A. G. Kfoury, J. Stehlik, C. H. Selzman, B. B. Reid, K. Brunisholz, D. R. Verma, C. Myrick, F. B. Sachse, D. Y. Li, and E. W. Hsu. Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation. NMR Biomed, 27(11):1378-86, 2014. Published, 11/2014.
• J. Lichter, E. Carruth, C. Mitchell, A. S. Barth, T. Aiba, D. A. Kass, G. F. Tomaselli, J. H. Bridge, and F. B. Sachse. Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy. J Mol Cell Cardiol, 72:186-195, 2014. Published, 04/2014.
• W. Wu, F. B. Sachse, A. Gardner, and M. C. Sanguinetti. Stoichiometry of altered hERG1 channel gating by small molecule activators. J Gen Physiol, 143(4):499-512, 2014. Published, 04/2014.
• N. S. Torres, F. B. Sachse, L. Izu, J. I. Goldhaber, K. W. Spitzer, and J. H. Bridge. A modified local control model for Ca2+ transients in cardiomyocytes: Junctional flux is accompanied by release from adjacent non-junctional RyRs. J Mol Cell Cardiol, 68:1-11, 2014. Published, 04/2014.
• Wozniak CJ, Stehlik J, Baird BC, McKellar SH, Song HK, Drakos SG, Selzman CH (2014). Ventricular assist devices or inotropic agents in status 1A patients? Survival analysis of the United Network of Organ Sharing database. Ann Thorac Surg, 97(4), 1364-71; discussion 1371-2.
• Lopez-Izquierdo A, Warren M, Riedel M, Cho S, Lai S, Lux RL, Spitzer KW, Benjamin IJ, Tristani-Firouzi M, Jou CJ (2014). A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes. Am J Physiol Heart Circ Physiol, 307(9), H1370-7.
• Ward RM, Drover DR, Hammer GB, Stemland CJ, Kern S, Tristani-Firouzi M, Lugo RA, Satterfield K, Anderson BJ (2014). The pharmacokinetics of methadone and its metabolites in neonates, infants, and children. Paediatr Anaesth, 24(6), 591-601.
• Riedel M, Jou CJ, Lai S, Lux RL, Moreno AP, Spitzer KW, Christians E, Tristani-Firouzi M, Benjamin IJ (2014). Functional and pharmacological analysis of cardiomyocytes differentiated from human peripheral blood mononuclear-derived pluripotent stem cells. Stem Cell Reports, 3(1), 131-41.
• Aromolaran AS, Subramanyam P, Chang DD, Kobertz WR, Colecraft HM (2014). LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms. Cardiovasc Res, 104(3), 501-11.
• Chaudhuri D, Clapham DE. Outstanding questions regarding the permeation, selectivity, and regulation of the mitochondrial calcium uniporter. Biochem Biophys Res Commun. 2014 Jul 11;
• Blauer JJ, Swenson D, Higuchi K, Plank G, Ranjan R, Marrouche N, Macleod RS. Sensitivity and specificity of substrate mapping: an in silico framework for the evaluation of electroanatomical substrate mapping strategies. J Cardiovasc Electrophysiol 2014 Jul ; 25 7 : 774-80
• Milanič M, Jazbinšek V, Macleod RS, Brooks DH, Hren R. Assessment of regularization techniques for electrocardiographic imaging. J Electrocardiol 2014 Jan-Feb ; 47 1 : 20-8
• McGann C, Akoum N, Patel A, Kholmovski E, Revelo P, Damal K, Wilson B, Cates J, Harrison A, Ranjan R, Burgon NS, Greene T, Kim D, Dibella EV, Parker D. Atrial fibrillation ablation outcome is predicted by left atrial remodeling on MRI.Circ Arrhythm Electrophysiol 2014 Feb ; 7 1 : 23-30
• Cates J, Bieging E, Morris A, Gardner G, Akoum N, Kholmovski E, Marrouche N, McGann C, MacLeod RS. Computational Shape Models Characterize Shape Change of the Left Atrium in Atrial Fibrillation.Clin Med Insights Cardiol 2014 ; 8 Suppl 1 : 99-109

2013

• Samson SC, Ferrer T, Jou CJ, Sachse FB, Shankaran SS, Shaw RM, Chi NC, Tristani-Firouzi M, Yost HJ (2013). 3-OST-7 regulates BMP-dependent cardiac contraction. PLoS Biol, 11(12), e1001727.
• Smyth JW, Shaw RM (2013). Autoregulation of connexin43 gap junction formation by internally translated isoforms. Cell Rep, 5(3), 611-8.
• Shaw RM, Colecraft HM (2013). L-type calcium channel targeting and local signalling in cardiac myocytes. Cardiovasc Res, 98(2), 177-86.
• Gao D, Zhang L, Dhillon R, Hong TT, Shaw RM, Zhu J (2013). Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart. PLoS ONE, 8(4), e60967.
• Drakos SG, Wever-Pinzon O, Selzman CH, Gilbert EM, Alharethi R, Reid BB, Saidi A, Diakos NA, Stoker S, Davis ES, Movsesian M, Li DY, Stehlik J, Kfoury AG, UCAR Utah Cardiac Recovery Program Investigators (2013). Magnitude and time course of changes induced by continuous-flow left ventricular assist device unloading in chronic heart failure: insights into cardiac recovery. J Am Coll Cardiol, 61(19), 1985-94.
• Wever-Pinzon O, Selzman CH, Drakos SG, Saidi A, Stoddard GJ, Gilbert EM, Labedi M, Reid BB, Davis ES, Kfoury AG, Li DY, Stehlik J, Bader F (2013). Pulsatility and the risk of nonsurgical bleeding in patients supported with the continuous-flow left ventricular assist device HeartMate II. Circ Heart Fail, 6(3), 517-26.
• Wever-Pinzon O, Kfoury AG, Selzman CH, Li DY, Drakos SG (2013). Left ventricular assist devices in chronic heart failure: more questions than answers? J Am Coll Cardiol, 62(23), 2257-8.
• Healy AH, Baird BC, Drakos SG, Stehlik J, Selzman CH (2013). Impact of ventricular assist device complications on posttransplant survival: an analysis of the United network of organ sharing database. Ann Thorac Surg, 95(3), 870-5.
• Wever-Pinzon O, Drakos SG, Kfoury AG, Nativi JN, Gilbert EM, Everitt M, Alharethi R, Brunisholz K, Bader FM, Li DY, Selzman CH, Stehlik J (2013). Morbidity and mortality in heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing thoracic organ allocation policy justified? Circulation, 127(4), 452-62.
• Monte E, Mouillesseaux K, Chen H, Kimball T, Ren S, Wang Y, Chen JN, Vondriska TM, Franklin S (2013). Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. Am J Physiol Heart Circ Physiol, 305(11), H1624-38.
• Lu G, Ota A, Ren S, Franklin S, Rau CD, Ping P, Lane TF, Zhou ZH, Reue K, Lusis AJ, Vondriska T, Wang Y (2013). PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Mol Metab, 2(4), 405-16.
• Fitts M, Breton E, Kholmovski EG, Dosdall DJ, Vijayakumar S, Hong KP, Ranjan R, Marrouche NF, Axel L, Kim D (2013). Arrhythmia insensitive rapid cardiac T1 mapping pulse sequence. Magn Reson Med, 70(5), 1274-82.
• Higuchi K, Akkaya M, Koopmann M, Blauer JJ, Burgon NS, Damal K, Ranjan R, Kholmovski E, Macleod RS, Marrouche NF (2013). The effect of fat pad modification during ablation of atrial fibrillation: late gadolinium enhancement MRI analysis. Pacing Clin Electrophysiol, 36(4), 467-76.
• M. Sanguinetti, M. Tristani-Firouzi, and F. B. Sachse. Structural determinants and biophysical properties of hERG1 channel gating. In D. P. Zipes and J. Jalife, editors, Cardiac Electrophysiology: From Cell to Bedside, chapter 12. W. B. Saunders Company, 6. edition, 2013. Published, 11/2013.
• S. Bauer, J.-C. Edelmann, G. Seemann, F. B. Sachse, and O. Dössel. Estimating intracellular conductivity tensors from confocal microscopy of rabbit ventricular tissue. In Biomed Tech (Berl), volume 58, 2013. Published, 10/2013.
• R. A. Navarro-Polanco, I. A. Aréchiga-Figueroa, P. D. Salazar-Fajardo, D. E. Benavides-Haro, J. C. Rodríguez-Elías, F. B. Sachse, M. Tristani-Firouzi, J. A. Sánchez-Chapula, and E. G. Moreno-Galindo. Voltage sensitivity of M₂ muscarinic receptors underlies the delayed rectifier-like activation of ACh-gated K⁺ current by choline in feline atrial myocytes. J Physiol, 591:4273-86, 2013. Published, 06/2013.
• C. Huang, A. K. Kaza, R. W. Hitchcock, and F. B. Sachse. Identification of nodal tissue in the living heart using rapid scanning fiber-optics confocal microscopy and extracellular fluorophores. Circ Cardiovasc Imaging, 6(5):739-46, 2013. Published, 06/2013.
• T. Seidel, T. Dräbing, G. Seemann, and F. B. Sachse. A semi-automatic approach for segmentation of three-dimensional microscopic image stacks of cardiac tissue. In S. Ourselin, D. Rueckert, and N. Smith, editors, Lecture Notes in Computer Science, volume 7945, pages 300-7. Springer, 2013. Published, 06/2013.
• K. Sohn, A. R. Wende, E. D. Abel, A. P. Moreno, F. B. Sachse, and B. B. Punske. Absence of glucose transporter 4 diminishes electrical activity of mouse hearts during hypoxia. Exp Physiol, 98:746-57, 2013. Published, 02/2013.
• Carson P, Wertheimer J, Miller A, OConnor CM, Pina IL, Selzman C, Sueta C, She L, Greene D, Lee KL, Jones RH, Velazquez EJ (2013). Surgical Treatment for Ischemic Heart Failure (STICH) Trial: Mode of Death Results.LID – 10.1016/j.jchf.2013.04.012 [doi]. JACC Heart Fail, 1(5).
• Healy AH, Baird BC, Drakos SG, Stehlik J, Selzman CH (2013). Impact of ventricular assist device complications on posttransplant survival: an analysis of the United network of organ sharing database. Ann Thorac Surg, 95(3), 870-5.
• Stanfield JR, Selzman CH (2013). In vitro pulsatility analysis of axial-flow and centrifugal-flow left ventricular assist devices. J Biomech Eng, 135(3), 34505.
• Wever-Pinzon O, Drakos SG, Kfoury AG, Nativi JN, Gilbert EM, Everitt M, Alharethi R, Brunisholz K, Bader FM, Li DY, Selzman CH, Stehlik J (2013). Morbidity and mortality in heart transplant candidates supported with mechanical circulatory support: is reappraisal of the current United network for organ sharing thoracic organ allocation policy justified? Circulation, 127(4), 452-62.
• Sancak Y, Markhard AL, Kitami T, Kovács-Bogdán E, Kamer KJ, Udeshi ND, Carr SA, Chaudhuri D, Clapham DE, Li AA, Calvo SE, Goldberger O, Mootha VK. EMRE is an essential component of the mitochondrial calcium uniporter complex. Science. 2013 Dec 13;
• Sah R, Mesirca P, Mason X, Gibson W, Bates-Withers C, Van den Boogert M, Chaudhuri D, Pu WT, Mangoni ME, Clapham DE. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation. 2013 Jul 9;
• Chaudhuri D, Sancak Y, Mootha VK, Clapham DE. MCU encodes the pore conducting mitochondrial calcium currents. Elife. 2013 Jun 4;
• Wang D, Kirby RM, Macleod RS, Johnson CR. Inverse Electrocardiographic Source Localization of Ischemia: An Optimization Framework and Finite Element Solution.J Comput Phys 2013 Oct 1 ; 250 : 403-424;

2012

• Zhang SS, Shaw RM (2012). Multilayered regulation of cardiac ion channels. Biochim Biophys Acta, 1833(4), 876-85.
• Cogswell R, McGlothlin D, Kobashigawa E, Shaw R, De Marco T (2012). Performance of the REVEAL model in WHO Group 2 to 5 pulmonary hypertension: application beyond pulmonary arterial hypertension. J Heart Lung Transplant, 32(3), 293-8.
• Cogswell R, Kobashigawa E, McGlothlin D, Shaw R, De Marco T (2012). Validation of the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) pulmonary hypertension prediction model in a unique population and utility in the prediction of long-term survival. J Heart Lung Transplant, 31(11), 1165-70.
• Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM (2012). Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm, 9(6), 961-7.
• Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong TT, Shaw RM (2012). Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res, 110(7), 978-89.
• Smyth JW, Shaw RM (2012). Visualizing cardiac ion channel trafficking pathways. Methods Enzymol, 505, 187-202.
• Revelo MP, Miller DV, Stehlik J, Brunisholz K, Drakos S, Gilbert EM, Everitt M, Budge D, Alharethi R, Snow G, Hammond EH, Kfoury AG (2012). Longitudinal evaluation of microvessel density in survivors vs. nonsurvivors of cardiac pathologic antibody-mediated rejection. Cardiovasc Pathol, 21(6), 445-54.
• Bonios MJ, Terrovitis JV, Drakos SG, Katsaros F, Pantsios C, Nanas SN, Kanakakis J, Alexopoulos G, Toumanidis S, Anastasiou-Nana M, Nanas JN (2012). Comparison of three different regimens of intermittent inotrope infusions for end stage heart failure. Int J Cardiol, 159(3), 225-9.
• Drakos SG, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Terrovitis JV, Nanas JN, Li DY (2012). Bridge to recovery: understanding the disconnect between clinical and biological outcomes. Circulation, 126(2), 230-41.
• Frech TM, Revelo MP, Drakos SG, Murtaugh MA, Markewitz BA, Sawitzke AD, Li DY (2012). Vascular leak is a central feature in the pathogenesis of systemic sclerosis. J Rheumatol, 39(7), 1385-91.
• Wever-Pinzon O, Stehlik J, Kfoury AG, Terrovitis JV, Diakos NA, Charitos C, Li DY, Drakos SG (2012). Ventricular assist devices: pharmacological aspects of a mechanical therapy. Pharmacol Ther, 134(2), 189-99.
• Wozniak CJ, Baird BC, Stehlik J, Drakos SG, Bull DA, Patel AN, Selzman CH (2012). Improved survival in heart transplant patients living at high altitude. J Thorac Cardiovasc Surg, 143(3), 735-741.e1.
• Kfoury AG, Snow GL, Budge D, Alharethi RA, Stehlik J, Everitt MD, Miller DV, Drakos SG, Reid BB, Revelo MP, Gilbert EM, Selzman CH, Bader FM, Connelly JJ, Hammond ME (2012). A longitudinal study of the course of asymptomatic antibody-mediated rejection in heart transplantation. J Heart Lung Transplant, 31(1), 46-51.
• Hong T, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun;9(6):961-7. doi: 10.1016/j.hrthm.2012.01.024. PMCID: PMC3349006.
• Ranjan R, Kholmovski EG, Blauer J, Vijayakumar S, Volland NA, Salama ME, Parker DL, MacLeod R, Marrouche NF (2012). Identification and acute targeting of gaps in atrial ablation lesion sets using a real-time magnetic resonance imaging system. Circ Arrhythm Electrophysiol, 5(6), 1130-5.
• Akoum N, McGann C, Vergara G, Badger T, Ranjan R, Mahnkopf C, Kholmovski E, Macleod R, Marrouche N (2012). Atrial fibrosis quantified using late gadolinium enhancement MRI is associated with sinus node dysfunction requiring pacemaker implant. J Cardiovasc Electrophysiol, 23(1), 44-50.
• Ranjan R (2012). Magnetic resonance imaging in clinical cardiac electrophysiology. Crit Rev Biomed Eng, 40(5), 409-26.
• P. M. Kekenes-Huskey, Y. Cheng, J. E. Hake, F. B. Sachse, J. H. Bridge, M. J. Holst, J. A. McCammon, A. D. McCulloch, and A. P. Michailova. Modeling effects of l-type Ca²⁺ current and Na⁺-Ca²⁺ exchanger on Ca²⁺ trigger flux in rabbit myocytes with realistic t-tubule geometries. Front Physiol, 3:351, 2012. Published, 11/2012.
• T. G. McNary, K. W. Spitzer, H. Holloway, J. H. B. Bridge, P. Kohl, and F. B. Sachse. Mechanical modulation of the transverse tubular system of ventricular cardiomyocytes. Prog Biophys Mol Biol, 110:218-25, 2012. Published, 10/2012.
• E. M. Wülfers, N. S. Torres, G. Lenis, H. Li, G. Seemann, O. Dössel, J. H. B. Bridge, and F. B. Sachse. An automated approach to analyze microstructural remodeling from confocal microscopies of ventricular myocytes from diseased hearts. In Biomed Tech (Berl), 57-1, 46-49, 2012. Published, 10/2012.
• G. Seemann, R. Moss, A. K. E. Kurz, O. Dössel, M. Tristani-Firouzi, and F. B. Sachse. A 2-state markov model of I_KACh based on a membrane voltage dependent muscarinic M2 receptor approach. In Proc Comp Cardiol, 2012. Published, 10/2012.
• V. Garg, F. B. Sachse, and M. Sanguinetti. Tuning of EAG K⁺ channel inactivation: molecular determinants of amplification by mutations and a small molecule. J Gen Physiol, 140(3):307-24, 2012. Published, 09/2012.
• R. A. Lasher, A. Q. Pahnke, J. M. Johnson, F. B. Sachse, and R. W. Hitchcock. Electrical stimulation directs engineered cardiac tissue to an age-matched native phenotype. J Tissue Eng, 3(1):2041731412455354, 2012. Published, 07/2012.
• F. B. Sachse, N. S. Torres, E. Savio-Galimberti, T. Aiba, D. A. Kass, G. F. Tomaselli, and J. H. Bridge. Subcellular structures and function of myocytes impaired during heart failure are restored by cardiac resynchronization therapy. Circ Res, 110:588-97, 2012. Published, 02/2012.
• Selzman CH (2012). Invited commentary. Ann Thorac Surg, 94(6), 2024.
• Andersen NM, Stansfield WE, Tang RH, Rojas M, Patterson C, Selzman CH (2012). Recovery from decompensated heart failure is associated with a distinct, phase-dependent gene expression profile. J Surg Res, 178(1), 72-80.
• Andersen NM, Tang R, Li L, Javan H, Zhang XQ, Selzman CH (2012). Inhibitory kappa-B kinase-β inhibition prevents adaptive left ventricular hypertrophy. J Surg Res, 178(1), 105-9.
• Stanfield JR, Selzman CH, Pardyjak ER, Bamberg S (2012). Flow characteristics of continuous-flow left ventricular assist devices in a novel open-loop system. ASAIO J, 58(6), 590-6.
• Drakos SG, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Terrovitis JV, Nanas JN, Li DY (2012). Bridge to recovery: understanding the disconnect between clinical and biological outcomes. Circulation, 126(2), 230-41.
• Wozniak CJ, Baird BC, Stehlik J, Drakos SG, Bull DA, Patel AN, Selzman CH (2012). Improved survival in heart transplant patients living at high altitude. J Thorac Cardiovasc Surg, 143(3), 735-741.e1.
• Selzman CH, Desjardins G, Patel AN, Davis E, Dick S, Stehlik J (2012). Complications associated with the use of left ventricular assist device therapy in an adult patient with Ebstein’s anomaly. Ann Thorac Surg, 93(1), 297-9.
• Kfoury AG, Snow GL, Budge D, Alharethi RA, Stehlik J, Everitt MD, Miller DV, Drakos SG, Reid BB, Revelo MP, Gilbert EM, Selzman CH, Bader FM, Connelly JJ, Hammond ME (2012). A longitudinal study of the course of asymptomatic antibody-mediated rejection in heart transplantation. J Heart Lung Transplant, 31(1), 46-51.
• Blaufox AD, Tristani-Firouzi M, Seslar S, Sanatani S, Trivedi B, Fischbach P, Paul T, Young ML, Tisma-Dupanovic S, Silva J, Cuneo B, Fournier A, Singh H, Tanel RE, Etheridge SP (2012). Congenital long QT 3 in the pediatric population. Am J Cardiol, 109(10), 1459-65.

2011

• Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM (2011). BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm, 9(5), 812-20.
• Chen S, Law CS, Grigsby CL, Olsen K, Hong TT, Zhang Y, Yeghiazarians Y, Gardner DG. Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation. 2011 Oct 25;124(17):1838-47. doi: 10.1161/CIRCULATIONAHA.111.032680. Epub 2011 Sep 26. PubMed PMID: 21947295; PubMed Central PMCID: PMC4160312.
• Smyth JW, Shaw RM (2011). The gap junction life cycle. Heart Rhythm, 9(1), 151-3.
• Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olgun P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH (2011). Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A, 108(33), 13576-81.
• Dimopoulos S, Diakos N, Tseliou E, Tasoulis A, Mpouchla A, Manetos C, Katsaros L, Drakos S, Terrovitis J, Nanas S (2011). Chronotropic incompetence and abnormal heart rate recovery early after left ventricular assist device implantation. Pacing Clin Electrophysiol, 34(12), 1607-14.
• Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, Bader F, Alharethi R, Reid B, Selzman CH, Everitt MD, Kfoury AG, Stehlik J (2011). Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant, 11(12), 2755-61.
• Healy AH, Mason NO, Hammond ME, Reid BB, Clayson SE, Drakos SG, Kfoury AG, Patel AN, Bull DA, Budge D, Alharethi RA, Bader FM, Gilbert EM, Stehlik J, Selzman CH (2011). Allograft rejection in patients supported with continuous-flow left ventricular assist devices. Ann Thorac Surg, 92(5), 1601-7; discussion 1607.
• Pierrakos CN, Bonios MJ, Drakos SG, Charitos EI, Tsolakis EJ, Ntalianis A, Nanas SN, Charitos CE, Nanas JN, Terrovitis JV (2011). Mechanical assistance by intra-aortic balloon pump counterpulsation during reperfusion increases coronary blood flow and mitigates the no-reflow phenomenon: an experimental study. Artif Organs, 35(9), 867-74.
• Nativi JN, Drakos SG, Kucheryavaya AY, Edwards LB, Selzman CH, Taylor DO, Hertz MI, Kfoury AG, Stehlik J (2011). Changing outcomes in patients bridged to heart transplantation with continuous- versus pulsatile-flow ventricular assist devices: an analysis of the registry of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant, 30(8), 854-61.
• Chan AC, Drakos SG, Ruiz OE, Smith AC, Gibson CC, Ling J, Passi SF, Stratman AN, Sacharidou A, Revelo MP, Grossmann AH, Diakos NA, Davis GE, Metzstein MM, Whitehead KJ, Li DY (2011). Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice. J Clin Invest, 121(5), 1871-81.
• Drakos SG, Kfoury AG, Selzman CH, Verma DR, Nanas JN, Li DY, Stehlik J (2011). Left ventricular assist device unloading effects on myocardial structure and function: current status of the field and call for action. Curr Opin Cardiol, 26(3), 245-55.
• Drakos SG, Terrovitis JV, Nanas JN, Charitos EI, Ntalianis AS, Malliaras KG, Diakos N, Koudoumas D, Theodoropoulos S, Yacoub MH, Anastasiou-Nana MI (2011). Reverse electrophysiologic remodeling after cardiac mechanical unloading for end-stage nonischemic cardiomyopathy. Ann Thorac Surg, 91(3), 764-9.
• Stavrakis S, Terrovitis J, Tsolakis E, Drakos S, Dalianis A, Bonios M, Koudoumas D, Malliaras K, Nanas J (2011). Relationship between retrograde coronary blood flow and the extent of no-reflow and infarct size in a porcine ischemia-reperfusion model. J Cardiovasc Transl Res, 4(1), 99-105.
• Hong T, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012 May;9(5):812-20. doi: 10.1016/j.hrthm.2011.11.055. PMCID: PMC3306544.
• Ranjan R, Kato R, Zviman MM, Dickfeld TM, Roguin A, Berger RD, Tomaselli GF, Halperin HR (2011). Gaps in the ablation line as a potential cause of recovery from electrical isolation and their visualization using MRI. Circ Arrhythm Electrophysiol, 4(3), 279-86.
• R. H. Clayton, O. M. Bernus, E. M. Cherry, H. Dierckx, F. H. Fenton, D. Olmos Liceaga, L. Mirabella, A.V. Panfilov, F. B. Sachse, G. Seemann, and H. Zhang. Models of cardiac tissue electrophysiology: Progress, challenges and open questions. Prog Biophys Mol Biol, 104:22-48, 2011. Published, 06/2011.
• M. Fink, S. A. Niederer, E. M. Cherry, F. H. Fenton, J. T. Koivumäki, G. Seemann, R. Thul, H. Zhang, F. B. Sachse, D. Beard, E. J. Crampin, and N. P. Smith. Cardiac cell modelling: Observations from the heart of the cardiac physiome project. Prog Biophys Mol Biol, 104:2-21, 2011. Published, 06/2011.
• N. Decher, K. Wemhoener, S. Rinne, M. F. Netter, M. Zuzarte, M. I. Aller, S. G. Kaufmann, X. T. Li, J. Daut, F. B. Sachse, and S. K. G. Maier. Knock-out of the potassium channel TASK-1 leads to a prolonged QT interval and a disturbed QRS complex. Cell Physiol Biochem, 28(1):77-86, 2011. Published, 06/2011.
• M. Grunnet, J. Abbruzesse, F. B. Sachse, and M. C. Sanguinetti. Molecular determinants of hERG1 K+ channel activation by NS1643. Mol Pharmacol, 79(1):1-9, 2011. Published, 06/2011.
• V. Garg, A. Stary-Weinzinger, F. B. Sachse, and M. Sanguinetti. Molecular determinants for activation of human ether-a-go-go related gene 1 potassium channels by 3-nitro-N-(4-phenoxyphenyl) benzamide. Mol Pharmacol, 80(4):630-7, 2011. Published, 06/2011.
• S. H. Limberg, M. F. Netter, C. Rolfes, S. Rinne, G. Schlichthoerl, M. Zuzarte, T. Vassiliou, R. Moosdorf, H. Wulf, J. Daut, F. B. Sachse, and N. Decher. TASK-1 channels may modulate action potential duration of human atrial cardiomyocytes. Cell Physiol Biochem, 28:613-24, 2011. Published, 06/2011.
• D. P. Lackey, E. D. Carruth, R. A. Lasher, J. Boenisch, F. B. Sachse, and R. W. Hitchcock. Three-dimensional modeling and quantitative analysis of gap junction distributions in cardiac tissue. Ann Biomed Eng, 39(11):2683-94, 2011. Published, 06/2011.
• S. A. Niederer, E. Kerfoot, A. P. Benson, O. Bernus, M. O. Bernabeu, C. Bradley, E. M. Cherry, R. Clayton, F. H. Fenton, A. Garny, E. Heidenreich, S. Land, M. Maleckar, P. Pathmanathan, G. Plank, J. F. Rodríguez, I. Roy, F. B. Sachse, G. Seemann, O. Skavhaug, and N. P. Smith. Verification of cardiac tissue electrophysiology simulators using an N-version benchmark. Philos Transact A Math Phys Eng Sci, 369(1954):4331-51, 2011. Published, 06/2011.
• E. G. Moreno-Galindo, J. A. Sánchez-Chapula, F. B. Sachse, J. A. Rodriguez-Paredes, M. Tristani-Firouzi, and R. A. Navarro-Polanco. Relaxation gating of the acetylcholine-activated inward rectifier K+ current (IKACh) is mediated by intrinsic voltage-sensitivity of the muscarinic receptor. J Physiol, 589(7):1755-67, 2011. Published, 06/2011.
• K. Sohn, F. B. Sachse, A. P. Moreno, P. R. Ershler, A. R. Wende, E. D. Abel, and B. B. Punske. The maximal downstroke of epicardial potentials as an index of electrical activity in mouse heart. IEEE Trans Biomed Eng, 58(11):3175-83, 2011. Published, 06/2011.
• T. A. Quinn, S. Granite, M. A. Allessie, C. Antzelevitch, C. Bollensdorff, G. Bub, R. A. B. Burton, E. Cerbai, P. S. Chen, M. Delmar, D. DiFrancesco, Y. E. Earm, I. R. Efimov, M. Egger, E. Entcheva, M. Fink, R. Fischmeister, M. R. Franz, A. Garny, W. R. Giles, T. Hannes, S. E. Harding, P. J. Hunter, G. Iribe, J. Jalife, C. R. Johnson, R. S. Kass, I. Kodama, G. Koren, P. Lord, V. S. Markhasin, S. Matsuoka, A. D. McCulloch, G. R. Mirams, G. E. Morley, S. Nattel, D. Noble, S. P. Olesen, A. V. Panfilov, N. A. Trayanova, U. Ravens, S. Richard, D. S. Rosenbaum, Y. Rudy, F. Sachs, F. B. Sachse, D. A. Saint, U. Schotten, O. Solovyova, P. Taggart, L. Tung, A. Varró, P.G. Volders, K. Wang, J. N. Weiss, E. Wettwer, E. White, R. Wilders, R. L. Winslow, and P. Kohl. Minimum information about a cardiac electrophysiology experiment (MICEE): Standardised reporting for model reproducibility, interoperability, and data sharing. Prog Biophys Mol Biol, 107(1):4-10, 2011. Published, 06/2011.
• T. G. McNary, J. H. Bridge, and F. B. Sachse. Strain transfer in ventricular cardiomyocytes to their transverse tubular system revealed by scanning confocal microscopy. Biophys J, 100(10):L53-55, 2011. Published, 05/2011.
• Wever Pinzon O, Stoddard G, Drakos SG, Gilbert EM, Nativi JN, Budge D, Bader F, Alharethi R, Reid B, Selzman CH, Everitt MD, Kfoury AG, Stehlik J (2011). Impact of donor left ventricular hypertrophy on survival after heart transplant. Am J Transplant, 11(12), 2755-61.
• Healy AH, Mason NO, Hammond ME, Reid BB, Clayson SE, Drakos SG, Kfoury AG, Patel AN, Bull DA, Budge D, Alharethi RA, Bader FM, Gilbert EM, Stehlik J, Selzman CH (2011). Allograft rejection in patients supported with continuous-flow left ventricular assist devices. Ann Thorac Surg, 92(5), 1601-7; discussion 1607.
• Nativi JN, Drakos SG, Kucheryavaya AY, Edwards LB, Selzman CH, Taylor DO, Hertz MI, Kfoury AG, Stehlik J (2011). Changing outcomes in patients bridged to heart transplantation with continuous- versus pulsatile-flow ventricular assist devices: an analysis of the registry of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant, 30(8), 854-61.
• Selzman CH (2011). Invited commentary. Ann Thorac Surg, 92(1), 153-4.
• Drakos SG, Kfoury AG, Selzman CH, Verma DR, Nanas JN, Li DY, Stehlik J (2011). Left ventricular assist device unloading effects on myocardial structure and function: current status of the field and call for action. Curr Opin Cardiol, 26(3), 245-55.
• Revelo MP, Stehlik J, Miller D, Snow GL, Everitt MD, Budge D, Bader FM, Alharethi RA, Gilbert EM, Reid BB, Selzman CH, Hammond ME, Kfoury AG (2011). Antibody testing for cardiac antibody-mediated rejection: which panel correlates best with cardiovascular death? J Heart Lung Transplant, 30(2), 144-50.q
• Palatinus, Joseph A, Joshua M Rhett, Robert G Gourdie, Enhanced PKC-epsilon mediated phosphorylation of connexin43 at serine 368 by a carboxyl-terminal mimetic peptide is dependent on injury. Channels (Austin). 2011 May 1;5 (3):236-40.
• Palatinus Joseph A, O’Quinn MP, Barker RJ, Harris BS, Jourdan J, Gourdie RG. ZO-1 determines adherens and gap junction localization at intercalated disks. Am J Physiol Heart Circ Physiol. 2011 Feb; 300 (2) :H583-94.
• O’Quinn MP, Palatinus JA, Harris BS, Hewett KW, Gourdie RG. A peptide mimetic of the connexin43 carboxyl terminus reduces ga≈):704-15.‘
• Vergara GR, Vijayakumar S, Kholmovski EG, Blauer JJ, Guttman MA, Gloschat C, Payne G, Vij K, Akoum NW, Daccarett M, McGann CJ, Macleod RS, Marrouche N. Real-time magnetic resonance imaging-guided radiofrequency atrial ablation and visualization of lesion formation at 3 Tesla.Heart Rhythm 2011 Feb ; 8 2 : 295-303;
• Swenson DJ, Geneser SE, Stinstra JG, Kirby RM, MacLeod RS. Cardiac position sensitivity study in the electrocardiographic forward problem using stochastic collocation and boundary element methods.Ann Biomed Eng 2011 Dec ; 39 12 : 2900-10;
• Isaacson BM, Stinstra JG, Bloebaum RD, Pasquina PF, MacLeod RS. Establishing multiscale models for simulating whole limb estimates of electric fields for osseointegrated implants.IEEE transactions on bio-medical engineering 2011 ; 58 10 : 2991-4;

2010

• Smyth JW, Shaw RM (2010). Forward trafficking of ion channels: what the clinician needs to know. Heart Rhythm, 7(8), 1135-40.
• Hong TT, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM (2010). BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol, 8(2), e1000312.
• Brush S, Budge D, Alharethi R, McCormick AJ, MacPherson JE, Reid BB, Ledford ID, Smith HK, Stoker S, Clayson SE, Doty JR, Caine WT, Drakos S, Kfoury AG (2010). End-of-life decision making and implementation in recipients of a destination left ventricular assist device. J Heart Lung Transplant, 29(12), 1337-41.
• Verma DR, Drakos SG, Stehlik J, Horne BD, Kfoury AG (2010). Effect of preservation solution choice on antibody-mediated rejection after heart transplantation. J Heart Lung Transplant, 29(11), 1314-5.
• Singhal AK, Drakos SG, Kfoury AG, Horne BD, Verma DR, Stehlik J (2010). Prolonged allograft ischemic time is not associated with higher incidence of antibody-mediated rejection. J Heart Lung Transplant, 29(10), 1198-200.
• Tasoulis A, Papazachou O, Dimopoulos S, Gerovasili V, Karatzanos E, Kyprianou T, Drakos S, Anastasiou-Nana M, Roussos C, Nanas S (2010). Effects of interval exercise training on respiratory drive in patients with chronic heart failure. Respir Med, 104(10), 1557-65.
• Kotter JR, Drakos SG, Horne BD, Hammond EH, Stehlik J, Bull DA, Reid BB, Gilbert EM, Everitt M, Alharethi R, Budge D, Verma DR, Li DY, Kfoury AG (2010). Effect of blood product transfusion-induced tolerance on incidence of cardiac allograft rejection. Transplant Proc, 42(7), 2687-92.
• Dimopoulos SK, Drakos SG, Terrovitis JV, Tzanis GS, Nanas SN (2010). Improvement in respiratory muscle dysfunction with continuous-flow left ventricular assist devices. J Heart Lung Transplant, 29(8), 906-8.
• Drakos SG, Kfoury AG, Hammond EH, Reid BB, Revelo MP, Rasmusson BY, Whitehead KJ, Salama ME, Selzman CH, Stehlik J, Clayson SE, Bristow MR, Renlund DG, Li DY (2010). Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart. J Am Coll Cardiol, 56(5), 382-91.
• Bull DA, Reid BB, Selzman CH, Mesley R, Drakos S, Clayson S, Stoddard G, Gilbert E, Stehlik J, Bader F, Kfoury A, Budge D, Eckels DD, Fuller A, Renlund D, Patel AN (2010). The impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation. J Thorac Cardiovasc Surg, 140(1), 169-73.
• Drakos SG, Janicki L, Horne BD, Kfoury AG, Reid BB, Clayson S, Horton K, Haddad F, Li DY, Renlund DG, Fisher PW (2010). Risk factors predictive of right ventricular failure after left ventricular assist device implantation. Am J Cardiol, 105(7), 1030-5.
• Bonios MJ, Pierrakos CN, Argiriou M, Dalianis A, Terrovitis JV, Dolou P, Drakos SG, Koudoumas D, Charitos CE, Anastasiou-Nana MI (2010). Increase in coronary blood flow by intra-aortic balloon counterpulsation in a porcine model of myocardial reperfusion. Int J Cardiol, 138(3), 253-60.
• Drakos SG, Athanasoulis T, Malliaras KG, Terrovitis JV, Diakos N, Koudoumas D, Ntalianis AS, Theodoropoulos SP, Yacoub MH, Nanas JN (2010). Myocardial sympathetic innervation and long-term left ventricular mechanical unloading. JACC Cardiovasc Imaging, 3(1), 64-70.
• Robichaux RP, Dosdall DJ, Osorio J, Garner NW, Li L, Huang J, Ideker RE (2010). Periods of highly synchronous, non-reentrant endocardial activation cycles occur during long-duration ventricular fibrillation. J Cardiovasc Electrophysiol, 21(11), 1266-73.
• Dosdall DJ, Fast VG, Ideker RE (2010). Mechanisms of defibrillation. Annu Rev Biomed Eng, 12, 233-58.
• Franklin S, Zhang M, Chen H, Paulsson AK, Mitchell-Jordan SA, Li Y, Ping P, Vondriska TM (2010). Specialized compartments of cardiac nuclei exhibit distinct proteome anatomy. Mol Cell Proteomics, 10(1).
• Hong T, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM. BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb 16;8(2):e1000312. doi: 10.1371/journal.pbio.1000312. PMCID: PMC2821894.
• Ranjan R, Henrikson CA (2010). ICD implantation after crossing a totally occluded subclavian vein via collaterals from the superior vena cava. Pacing Clin Electrophysiol, 33(2), e14-6.
• F. B. Sachse. Patient-specific modeling of structure and function of cardiac cells. In R. C. P. Kerckhoffs, editor, Patient-Specific Modeling of the Cardiovascular System, chapter 3, pages 43-61. Springer, Berlin, Heidelberg, New York, 1. edition, 2010. ISBN: 978-1-4419-6690-2. Published, 10/2010.
• T. G. McNary, J. H. B. Bridge, and F. B. Sachse. Change in ellipticity of transverse tubules during strain in rabbit ventricular myocytes. In Proc 6th Annual Mountain West Biomedical Engineering Conference, 2010. Published, 09/2010.
• G. Seemann, F. B. Sachse, M. Karl, D. L. Weiss, V. Heuveline, and O. Dössel. Framework for modular, flexible and efficient solving the cardiac bidomain equation using PETSc. In Prog Industrial Math ECMI 2008, Mathematics in Industry, pages 363-70, Berlin, Heidelberg, New York, 2010. Springer. Published, 08/2010.
• J. Abbruzzese, F. B. Sachse, M. Tristani-Firouzi, and M. C. Sanguinetti. Modification of hERG1 channel gating by Cd2+. J Gen Physiol, 136(2):203-24. Published, 05/2010.
• E. G. Moreno-Galindo, G. F. Barrio-Echavarria, J. C. Vasquez, N. Decher, F. B. Sachse, M. Tristani-Firouzi, J. A. Sanchez-Chapula, and R. A. Navarro-Polanco. Molecular basis for a high-potency open channel block of Kv1.5 channel by the endocannabinoid anandamide. Mol Pharmacol, 77(5):751-8, 2010. Published, 05/2010.
• N. S. Torres, A. Rock, E. Savio-Galimberti, F. B. Sachse, and J. H. B. Bridge. Occurrence of spontaneous sparks in ventricular myocytes from junctional and non-junctional RyR clusters. In Biophys J (Annual Meeting Abstracts), 2010. Published, 02/2010.
• N. S. Torres, R. Larbig, A. Rock, F. B. Sachse, K. D. Philipson, J. I. Goldhaber, and J. H. B. Bridge. Sodium current-induced release of calcium from the sarcoplasmic reticulum in rabbit ventricular myocytes. In Biophys J (Annual Meeting Abstracts), 2010. Published, 02/2010.
• Drakos SG, Kfoury AG, Hammond EH, Reid BB, Revelo MP, Rasmusson BY, Whitehead KJ, Salama ME, Selzman CH, Stehlik J, Clayson SE, Bristow MR, Renlund DG, Li DY (2010). Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart. J Am Coll Cardiol, 56(5), 382-91.
• Bull DA, Reid BB, Selzman CH, Mesley R, Drakos S, Clayson S, Stoddard G, Gilbert E, Stehlik J, Bader F, Kfoury A, Budge D, Eckels DD, Fuller A, Renlund D, Patel AN (2010). The impact of bridge-to-transplant ventricular assist device support on survival after cardiac transplantation. J Thorac Cardiovasc Surg, 140(1), 169-73.
• Selzman C (2010). Invited commentary. Ann Thorac Surg, 90(1), 123.
• Nativi JN, Kfoury AG, Myrick C, Peters M, Renlund D, Gilbert EM, Bader F, Singhal AK, Everitt M, Fisher P, Bull DA, Selzman C, Stehlik J (2010). Effects of the 2006 U.S. thoracic organ allocation change: analysis of local impact on organ procurement and heart transplantation. J Heart Lung Transplant, 29(3), 235-9.
• Raymond AL, Kfoury AG, Bishop CJ, Davis ES, Goebel KM, Stoker S, Selzman CH, Clayson SE, Smith H, Cowley CG, Alharethi R, Budge D, Reid BB (2010). Obesity and left ventricular assist device driveline exit site infection. ASAIO J, 56(1), 57-60.

2009

• Smyth JW, Hong TT, Gao D, Vogan JM, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM (2009). Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest, 120(1), 266-79.
• Shaw RM, Rudy Y (2009). Cardiac muscle is not a uniform syncytium. Biophys J, 98(12), 3102-3; discussion 3104-5.
• Singhal AK, Sheng X, Drakos SG, Stehlik J (2009). Impact of donor cause of death on transplant outcomes: UNOS registry analysis. Transplant Proc, 41(9), 3539-44.
• Gerovasili V, Drakos S, Kravari M, Malliaras K, Karatzanos E, Dimopoulos S, Tasoulis A, Anastasiou-Nana M, Roussos C, Nanas S (2009). Physical exercise improves the peripheral microcirculation of patients with chronic heart failure. J Cardiopulm Rehabil Prev, 29(6), 385-91.
• Kanakakis J, Nanas JN, Tsagalou EP, Maroulidis GD, Drakos SG, Ntalianis AS, Tzoumele P, Skoumbourdis E, Charbis P, Rokas S, Anastasiou-Nana M (2009). Multicenter randomized trial of facilitated percutaneous coronary intervention with low-dose tenecteplase in patients with acute myocardial infarction: the Athens PCI trial. Catheter Cardiovasc Interv, 74(3), 398-405.
• Drakos SG, Bonios MJ, Anastasiou-Nana MI, Tsagalou EP, Terrovitis JV, Kaldara E, Maroulidis G, Nanas SN, Kanakakis J, Nanas JN (2009). Long-term survival and outcomes after hospitalization for acute myocardial infarction complicated by cardiogenic shock. Clin Cardiol, 32(8), E4-8.
• Drakos SG, Kfoury AG, Kotter JR, Reid BB, Clayson SE, Selzman CH, Stehlik J, Fisher PW, Merida M 3rd, Eckels DD, Brunisholz K, Horne BD, Stoker S, Li DY, Renlund DG (2009). Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of post-implantation human leukocyte antigen-allosensitization. J Heart Lung Transplant, 28(8), 838-42.
• Kfoury AG, Hammond ME, Snow GL, Drakos SG, Stehlik J, Fisher PW, Reid BB, Everitt MD, Bader FM, Renlund DG (2009). Cardiovascular mortality among heart transplant recipients with asymptomatic antibody-mediated or stable mixed cellular and antibody-mediated rejection. J Heart Lung Transplant, 28(8), 781-4.
• Malliaras KG, Terrovitis JV, Drakos SG, Nanas JN (2009). Reverse cardiac remodeling enabled by mechanical unloading of the left ventricle. J Cardiovasc Transl Res, 2(1), 114-25.
• Drakos SG, Kanakakis JV, Nanas S, Bonios M, Kaldara E, Katsaros F, Pantsios C, Nanas JN (2009). Intermittent inotropic infusions combined with prophylactic oral amiodarone for patients with decompensated end-stage heart failure. J Cardiovasc Pharmacol, 53(2), 157-61.
• Whitehead KJ, Chan AC, Navankasattusas S, Koh W, London NR, Ling J, Mayo AH, Drakos SG, Jones CA, Zhu W, Marchuk DA, Davis GE, Li DY (2009). The cerebral cavernous malformation signaling pathway promotes vascular integrity via Rho GTPases. Nat Med, 15(2), 177-84.
• Tsagalou EP, Kanakakis J, Anastasiou-Nana MI, Drakos SG, Ntalianis AS, Malliaras K, Lazaris N, Katsaros F, Nanas JN (2009). Hemodynamic effects of levosimendan in acute myocardial infarction complicated by cardiogenic shock and high systemic vascular resistance. Acute Card Care, 11(2), 99-106.
• Yannopoulos D, Zviman M, Castro V, Kolandaivelu A, Ranjan R, Wilson RF, Halperin HR (2009). Intra-cardiopulmonary resuscitation hypothermia with and without volume loading in an ischemic model of cardiac arrest. Circulation, 120(14), 1426-35.
• Special Issue: Functional Imaging and Modeling of the Heart. Med Image Anal, 13(2):345, 2009. Published, 06/2009.
• T. G. McNary and F. B. Sachse. Modeling effects of strain-modulated membrane capacitance and conductance of K+ inward-rectifier on conduction velocity in cardiac tissue. In Proc Comp Cardiol. Published, 2009.
• F. B. Sachse, E. Savio-Galimberti, J. I. Goldhaber, and J. H. B. Bridge. Towards computational modeling of excitation-contraction coupling in cardiac myocytes: Reconstruction of structures and proteins from confocal imaging. In Pac Symp Biocomp, volume 14, pages 328-39. Published, 2009.
• K. Sohn, B. B. Punske, and F. B. Sachse. Relationship between maximal upstroke velocity of transmembrane voltage and minimum time derivative of extracellular potential. In Lecture Notes in Computer Science, volume 5528, pages 505-12. Springer. Published, 2009.
• R. A. Lasher, R. W. Hitchcock, and F. B. Sachse. Towards modeling of cardiac micro-structure with catheter-based confocal microscopy: A novel approach for dye delivery and tissue characterization. IEEE Trans Med Imaging, 28(8):1156-64. Published, 2009.
• A. Lopez-Izquierdo, D. Ponce-Balbuena, T. Ferrer, F. B. Sachse, M. Tristani-Firouzi, and J. A. Sánchez-Chapula. Chloroquine blocks a mutant Kir2.1 channel responsible for short QT syndrome and normalizes repolarization properties in silico. Cell Physiol Biochem, 24(3-4):153-60. Published, 2009.
• M. D. Perry, F. B. Sachse, J. Abbruzzese, and M. C. Sanguinetti. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance. Proc Natl Acad Sci U S A, 106(47):20075-80. Published, 2009.
• F. B. Sachse, A. P. Moreno, G. Seemann, and J. A. Abildskov. A model of electrical conduction in cardiac tissue including fibroblasts. Ann Biomed Eng, 37(5):874-89. Published, 2009.
• F. B. Sachse and G. Seemann. Special issue: Functional imaging and modelling of the heart. Med Image Anal, 13(2):345. Published, 2009.
• Stansfield WE, Andersen NM, Tang RH, Selzman CH (2009). Periostin is a novel factor in cardiac remodeling after experimental and clinical unloading of the failing heart. Ann Thorac Surg, 88(6), 1916-21.
• Campbell RA, Overmyer KA, Selzman CH, Sheridan BC, Wolberg AS (2009). Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability. Blood, 114(23), 4886-96.
• Kouretas PC, Kaza AK, Burch PT, Witte MK, Clayson SE, Everitt MD, Selzman CH (2009). Experience with the Levitronix CentriMag in the pediatric population as a bridge to decision and recovery. Artif Organs, 33(11), 1002-4.
• Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ (2009). MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest, 119(9), 2772-86.
• Drakos SG, Kfoury AG, Kotter JR, Reid BB, Clayson SE, Selzman CH, Stehlik J, Fisher PW, Merida M 3rd, Eckels DD, Brunisholz K, Horne BD, Stoker S, Li DY, Renlund DG (2009). Prior human leukocyte antigen-allosensitization and left ventricular assist device type affect degree of post-implantation human leukocyte antigen-allosensitization. J Heart Lung Transplant, 28(8), 838-42.
• Selzman C (2009). Invited commentary. Ann Thorac Surg, 88(1), 53.
• Kouretas PC, Kaza AK, Burch PT, Witte MK, Clayson SE, Everitt MD, Selzman CH (2009). Experience with the Levitronix CentriMag in the pediatric population as a bridge to decision and recovery. Artif Organs, 33(11), 1002-4.
• Jones RH, Velazquez EJ, Michler RE, Sopko G, Oh JK, OConnor CM, Hill JA, Menicanti L, Sadowski Z, Desvigne-Nickens P, Rouleau JL, Lee KL, STICH Hypothesis 2 Investigators (2009). Coronary bypass surgery with or without surgical ventricular reconstruction. N Engl J Med, 360(17), 1705-17.
• Willis MS, Rojas M, Li L, Selzman CH, Tang RH, Stansfield WE, Rodriguez JE, Glass DJ, Patterson C (2009). Muscle ring finger 1 mediates cardiac atrophy in vivo. Am J Physiol Heart Circ Physiol, 296(4), H997-H1006.
• Selzman C (2008). Invited commentary. Ann Thorac Surg, 87(3), 819.
• Stansfield WE, Charles PC, Tang RH, Rojas M, Bhati R, Moss NC, Patterson C, Selzman CH (2009). Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile. J Thorac Cardiovasc Surg, 137(1), 232-8, 238e1-8.
• Airey KJ, Etheridge SP, Tawil R, Tristani-Firouzi M (2009). Resuscitated sudden cardiac death in Andersen-Tawil syndrome. Heart Rhythm, 6(12), 1814-7.
• Rong YP, Bultynck G, Aromolaran AS, Zhong F, Parys JB, De Smedt H, Mignery GA, Roderick HL, Bootman MD, Distelhorst CW (2009). The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor. Proc Natl Acad Sci U S A, 106(34), 14397-402.
• Lew S, Wolters CH, Anwander A, Makeig S, MacLeod RS. Improved EEG source analysis using low-resolution conductivity estimation in a four-compartment finite element head model. Hum Brain Mapp 2009 Sep ; 30 9 : 2862-78;
• MacLeod RS, Stinstra JG, Lew S, Whitaker RT, Swenson DJ, Cole MJ, Krüger J, Brooks DH, Johnson CR. Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples. Philos Trans A Math Phys Eng Sci 2009 Jun 13 ; 367 1896 : 2293-310

2008

• Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D (2008). Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell, 16(2), 233-44.
• Smyth JW, Shaw RM (2008). Visualizing ion channel dynamics at the plasma membrane. Heart Rhythm, 5(6 Suppl), S7-11.
• Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, DiMaio JM, Srivastava D (2008). Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation, 117(17), 2224-31.
• Chi NC, Shaw RM, De Val S, Kang G, Jan LY, Black BL, Stainier DY (2008). Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev, 22(6), 734-9.
• Ntalianis AS, Drakos SG, Charitos C, Dolou P, Pierrakos CN, Terrovitis JV, Papaioannou T, Charitos E, Nanas JN (2008). Effects of intra-aortic balloon pump versus centrifugal pump on myocardial energetics and systemic circulation in a porcine model of rapidly worsening acute heart failure. ASAIO J, 54(6), 600-5.
• Drakos SG, Anastasiou-Nana MI, Terrovitis JV, Tsagalou EP, Kanakakis J, Ntalianis A, Lazaris N, Maroulidis G, Venetsanakos J, Bonios M, Nanas JN (2008). Intra-aortic balloon counterpulsation and delayed revascularization for myocardial infarction and shock in the absence of primary angioplasty: a treatment strategy with or without thrombolysis? Coron Artery Dis, 19(7), 521-6.
• Tsagalou EP, Anastasiou-Nana M, Agapitos E, Gika A, Drakos SG, Terrovitis JV, Ntalianis A, Nanas JN (2008). Depressed coronary flow reserve is associated with decreased myocardial capillary density in patients with heart failure due to idiopathic dilated cardiomyopathy. J Am Coll Cardiol, 52(17), 1391-8.
• Strber M, Sander K, Lahpor J, Ahn H, Litzler PY, Drakos SG, Musumeci F, Schlensak C, Friedrich I, Gustafsson R, Oertel F, Leprince P (2008). HeartMate II left ventricular assist device; early European experience. Eur J Cardiothorac Surg, 34(2), 289-94.
• Kravari M, Vasileiadis I, Gerovasili V, Karatzanos E, Tasoulis A, Kalligras K, Drakos SG, Dimopoulos S, Anastasiou-Nana M, Nanas S (2008). Effects of a 3-month rehabilitation program on muscle oxygenation in congestive heart failure patients as assessed by NIRS. Int J Ind Ergon.
• F. B. Sachse, E. Savio-Galimberti, J. I. Goldhaber, and J. H. B. Bridge. Sub-micrometer anatomical models of the sarcolemma of cardiac myocytes based on confocal imaging. Pac Symp Biocomp, 13:390-401, 2008. Published, 12/2008.
• F. B. Sachse, A. P. Moreno, and J. A. Abildskov. Electrophysiological modeling of fibroblasts and their interaction with myocytes. Ann Biomed Eng, 36(1):41-56, 2008. Published, 12/2008.
• A. A. Rodríguez-Menchaca, R. A. Navarro-Polanco, T. Ferrer-Villada, J. Rupp, F. B. Sachse, M. Tristani-Firouzi, and J. A. Sánchez-Chapula. The molecular basis of chloroquine block of the inward rectifier Kir2.1 channel. Proc Natl Acad Sci U S A, 105(4):1364-8, 2008. Published, 12/2008.
• E. Savio-Galimberti, J. Frank, M. Inoue, J. I. Goldhaber, M. B. Cannell, J. H. B. Bridge, and F. B. Sachse. Novel features of the rabbit transverse tubular system revealed by quantitative analysis of three-dimensional reconstructions from confocal images. Biophys J, 95:2053-62, 2008. Published, 12/2008.
• T. G. McNary, K. Sohn, B. Taccardi, and F. B. Sachse. Experimental and computational studies of strain-conduction velocity relationships in cardiac tissue. Prog Biophys Mol Biol.,97(2-3):383-400, 2008. Published, 12/2008.
• D. R. Piper, J. Rupp, F. B. Sachse, M. C. Sanguinetti, and M. Tristani-Firouzi. Cooperative interactions between R531 and basic residues in the voltage sensing module of hERG1 channels. Cell Physiol Biochem, 21:37-46, 2008. Published, 12/2008.
• N. Decher, T. Gonzalez, A. K. Streit, F. B. Sachse, V. Renigunta, M. Soom, S. H. Heineman, J. Daut, and M. C. Sanguinetti. Structural Determinants of Kvβ1.3 Induced Channel Inactivation: A Hairpin Modulated by PIP2. EMBO J, 27(23):3164-74, 2008. Published, 12/2008.
• D. Fernandez, J. Sargent, F. B. Sachse, and M. C. Sanguinetti. Structural basis for ether-a-go-go-related gene K+ channel subtype-dependent activation by niflumic acid. Mol Pharm, 3(4):1159-67, 2008. Published, 12/2008.
• Selzman CH (2008). Invited commentary on “Gene Transfer of endothelial nitric oxide synthase attenuates flow-induced pulmonary hypertension in rabbits. Ann Thorac Surg, 85, 585-6
• Rodriguez-Menchaca AA, Navarro-Polanco RA, Ferrer-Villada T, Rupp J, Tristani-Firouzi M, Sanchez-Chapula JA (2008). The structural basis of chloroquine block of the inward rectifier Kir2.1 channel. *corresponding author. Proc Natl Acad Sci U S A, 105(4), 1364-8.
• Rong YP, Aromolaran AS, Bultynck G, Zhong F, Li X, McColl K, Matsuyama S, Herlitze S, Roderick HL, Bootman MD, Mignery GA, Parys JB, De Smedt H, Distelhorst CW (2008). Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2’s inhibition of apoptotic calcium signals. Mol Cell, 31(2), 255-65.
• Geneser SE, Kirby RM, MacLeod RS. Application of stochastic finite element methods to study the sensitivity of ECG forward modeling to organ conductivity. IEEE Trans Biomed Eng 2008 Jan ; 55 1 : 31-40;
• Taccardi B, Punske BB, Macchi E, Macleod RS, Ershler PR. Epicardial and intramural excitation during ventricular pacing: effect of myocardial structure.Am J Physiol Heart Circ Physiol 2008 Apr ; 294 4 : H1753-66;

2007

• Drakos SG, Kfoury AG, Long JW, Stringham JC, Gilbert EM, Horne BD, Hagan MB, Nelson K, Renlund DG (2007). Similar transplantation outcomes in patients bridged with cardiac assist devices for acute cardiogenic shock versus chronic heart failure. Eur J Heart Fail, 9(8), 845-9.
• Drakos SG, Stringham JC, Long JW, Gilbert EM, Fuller TC, Campbell BK, Horne BD, Hagan ME, Nelson KE, Lindblom JM, Meldrum PA, Carlson JF, Moore SA, Kfoury AG, Renlund DG (2007). Prevalence and risks of allosensitization in HeartMate left ventricular assist device recipients: the impact of leukofiltered cellular blood product transfusions. J Thorac Cardiovasc Surg, 133(6), 1612-9.
• Hong TT, Huang J, Barrett TD, Lucchesi BR. Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis. Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H145-55. doi: 10.1152/ajpheart.00646.2007. Epub 2007 Oct 5. PubMed PMID: 17921331.
• Papazachou O, Anastasiou-Nana M, Sakellariou D, Tassiou A, Dimopoulos S, Venetsanakos J, Maroulidis G, Drakos S, Roussos C, Nanas S (2007). Pulmonary function at peak exercise in patients with chronic heart failure. Int J Cardiol, 118(1), 28-35.
• Drakos SG, Charitos EI, Nanas SN, Nanas JN (2007). Ventricular-assist devices for the treatment of chronic heart failure. Expert Rev Cardiovasc Ther, 5(3), 571-84.
• Drakos SG, Kfoury AG, Gilbert EM, Horne BD, Long JW, Stringham JC, Campbell BA, Renlund DG (2007). Effect of reversible pulmonary hypertension on outcomes after heart transplantation. J Heart Lung Transplant, 26(4), 319-23.
• Drakos SG, Kfoury AG, Gilbert EM, Long JW, Stringham JC, Hammond EH, Jones KW, Bull DA, Hagan ME, Folsom JW, Horne BD, Renlund DG (2007). Multivariate predictors of heart transplantation outcomes in the era of chronic mechanical circulatory support. Ann Thorac Surg, 83(1), 62-7.
• C. Putzke, K. Wemhöner, F. B. Sachse, S. Rinne, G. Schlichthörl, X. T. Lia, L. Jae, I. Eckhardt, E. Wischmeyer, H. Wulf, R. Preisig-Müller, J. Daut, and N. Decher. The acid-sensitive potassium channel TASK-1 in rat cardiac muscle. Cardiovasc Res, 75(1):59-68, 2007. Published, 12/2007.
• M. D. Perry, F. B. Sachse, and M. C. Sanguinetti. Structural basis of action for a human ether-a-go-go related gene 1 potassium channel activator. Proc Natl Acad Sci U S A, 104(34):13827-32, 2007. Published, 12/2007.
• G. Seemann, F. B. Sachse, D. L Weiss, L. J. Ptacek, and M. Tristani-Firouzi. Modeling of IK1 mutations in human left ventricular myocytes and tissue. Am J Physiol Heart Circ Physiol, 292(1):H549-59, 2007. Published, 12/2007.
• S. E. Geneser, R. M. Kirby, D. Xiu, and F. B. Sachse. Stochastic markovian modeling of electrophysiology of ion channels: Reconstruction of standard deviations in macroscopic currents. J Theor Biol, 245(4):627-637, 2007. Published, 12/2007.
• E. Savio, J. Frank, M. Inoue, J. Goldhaber, M. B. Cannell, J. H. B. Bridge, and F. B. Sachse. High-resolution three-dimensional confocal microscopy reveals novel structures in rabbit ventricular myocyte t-tubules. In Biophys. J (Annual Meeting Abstracts), 2007. Published, 01/2007.
• Riesenman PJ, Farber MA, Mauro MA, Selzman CH, Feins RH (2007). Aortoesophageal fistula after thoracic endovascular aortic repair and transthoracic embolization. J Vasc Surg, 46(4), 789-91.
• Moss NC, Stansfield WE, Willis MS, Tang RH, Selzman CH (2007). IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol, 293(4), H2248-53.
• Stansfield WE, Rojas M, Corn D, Willis M, Patterson C, Smyth SS, Selzman CH (2007). Characterization of a model to independently study regression of ventricular hypertrophy. J Surg Res, 142(2), 387-93.
• Selzman CH, Chang PP, Vernon-Platt T, Bowen A, Kowalczyk S, Sheridan BC (2007). Use of the Jarvik 2000 continuous flow left ventricular assist device for acute myocardial infarction and cardiogenic shock. J Heart Lung Transplant, 26(7), 756-8.
• Selzman CH, Sheridan BC (2007). Off-pump insertion of continuous flow left ventricular assist devices. J Card Surg, 22(4), 320-2.
• Stansfield WE, Moss NC, Willis MS, Tang R, Selzman CH (2007). Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury. Ann Thorac Surg, 84(1), 120-5.
• Selzman CH, Chang PP, Vernon-Platt T, Bowen A, Kowalczyk S, Sherican BC (2007). Use of the Jarvik 2000 continous flow left ventricular assist device for acute myocardial infarction and cardiogenic shock. J Heart Lung Transplant, 26(7), 756-8.
• Warshauer DM, Archer RK, Selzman CH, Tmaddon HS, Mauro MA (2007). Aortic pseudoaneurysm from penetrating superior vena cava stent. Radiology, 234(3), 901-4.
• Warshauer DM, Archer RK, Selzman CH, Tamaddon HS, Mauro MA (2007). Case 115: aortic pseudoaneurysm from penetrating superior vena cava stent. Radiology, 243(3), 901-4.
• Selzman C (2007). Invited commentary. Ann Thorac Surg, 83(5), 1758-9.
• Pellisson O, Kalaizich L, Ptacek LP, Tristani-Firouzi M, Gonzalez M (2007). Flecanide suppresses biventricular tachycardia and reverses tachycardia-induced cardiomyopathy in andersen-Tawil Syndrome. J Cardiovasc Electrophysiol, 9(3), 162-6.
• Arnaout R, Ferrer T, Huisken J Spitzer EK, Stainier DYR, Tristani-Firouzi M, Chi NC (2007). Zebrafish embryonic lethal kcnh2 null: pathologic model for human homozygous long QT2 syndrome. *corresponding author. Proc Natl Acad Sci U S A, 104(27), 11316-21.
• Pellizzn OA, Kalaizich L, Ptcek LJ, Tristani-Firouzi M, Gonzalez MD (2007). Flecainide suppresses bidirectional ventricular tachycardia and reverses tachycardia-induced cardiomyopathy in Andersen-Tawil syndrome. J Cardiovasc Electrophysiol, 19(1), 95-7.
• Aromolaran AS, Zima AV, Blatter LA (2007). Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. Am J Physiol Cell Physiol, 293(1), C106-18.
• Snopko RM, Aromolaran AS, Karko KL, Ramos-Franco J, Blatter LA, Mejía-Alvarez R (2007). Cell culture modifies Ca2+ signaling during excitation-contraction coupling in neonate cardiac myocytes. Cell Calcium, 41(1), 13-25.
• Herzig S, Khan IF, Gründemann D, Matthes J, Ludwig A, Michels G, Hoppe UC, Chaudhuri D, Schwartz A, Yue DT, Hullin R. Mechanism of Ca(v)1.2 channel modulation by the amino terminus of cardiac beta2-subunits. FASEB J. 2007 May;21(7):1527-38.
• Chaudhuri D, Issa JB, Yue DT. Elementary mechanisms producing facilitation of Cav2.1 (P/Q-type) channels. J Gen Physiol. 2007 May;129(5):385-401. doi: 10.1085/jgp.200709749. Epub 2007 Apr 16.

2006

• Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY (2006). Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell, 128(3), 547-60.
• Hong TT, Huang J, Lucchesi BR. Effect of thrombolysis on myocardial injury: recombinant tissue plasminogen activator vs. alfimeprase. Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H959-67. doi: 10.1152/ajpheart.00649.2005. Epub 2005 Oct 21. PubMed PMID: 16243915.
• Hong TT, Huang J, Driscoll E, Lucchesi BR. Preclinical evaluation of S18886 in an experimental model of coronary arterial thrombosis. J Cardiovasc Pharmacol. 2006 Nov;48(5):239-48. doi: 10.1097/01.fjc.0000248234.08277.7e. PubMed PMID: 17110806.

• Nanas JN, Matsouka C, Karageorgopoulos D, Leonti A, Tsolakis E, Drakos SG, Tsagalou EP, Maroulidis GD, Alexopoulos GP, Kanakakis JE, Anastasiou-Nana MI (2006). Etiology of anemia in patients with advanced heart failure. J Am Coll Cardiol, 48(12), 2485-9.
• Hong TT, Van Gorp CL, Cardin AD, Lucchesi BR. Intimatan (dermatan 4,6-O-disulfate) prevents rethrombosis after successful thrombolysis in the canine model of deep vessel wall injury. Thromb Res. 2006;117(3):333-42. doi: 10.1016/j.thromres.2005.03.018. PubMed PMID: 15893368.
• Drakos SG, Kfoury AG, Long JW, Stringham JC, Fuller TC, Nelson KE, Campbell BK, Gilbert EM, Renlund DG (2006). Low-dose prophylactic intravenous immunoglobulin does not prevent HLA sensitization in left ventricular assist device recipients. Ann Thorac Surg, 82(3), 889-93.
• Nanas SN, Nanas JN, Sakellariou DCh, Dimopoulos SK, Drakos SG, Kapsimalakou SG, Mpatziou CA, Papazachou OG, Dalianis AS, Anastasiou-Nana MI, Roussos C (2006). VE/VCO2 slope is associated with abnormal resting haemodynamics and is a predictor of long-term survival in chronic heart failure. Eur J Heart Fail, 8(4), 420-7.
• Terrovitis JV, Anastasiou-Nana MI, Alexopoulos GP, Tsolakis EJ, Margari ZJ, Drakos SG, Tsagalou EP, Papazoglou P, Efentakis S, Nanas JN (2006). Prevalence and prognostic significance of anemia in patients with congestive heart failure treated with standard vs high doses of enalapril. J Heart Lung Transplant, 25(3), 333-8.
• Drakos SG, Kfoury AG, Long JW, Stringham JC, Gilbert EM, Moore SA, Campbell BK, Nelson KE, Horne BD, Renlund DG (2006). Effect of mechanical circulatory support on outcomes after heart transplantation. J Heart Lung Transplant, 25(1), 22-8.
• Dimopoulos S, Anastasiou-Nana M, Sakellariou D, Drakos SG, Kapsimalakou S, Maroulidis G, Roditis P, Roussos C, Nanas S (2006). Effects of exercise rehabilitation program on heart rate recovery in patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil, 13(1), 67-73.
• Gray NA Jr, Selzman CH (2006). Current status of the total artificial heart. Am Heart J, 152(1), 4-10.
• Pathak A, Zhao R, Monroe DM, Roberts HR, Sheridan BC, Selzman CH, Stouffer GA (2006). Thrombin generation in vascular tissue. J Thromb Haemost, 4(1), 60-7.
• Selzman CH (2006). Invited commentary. Ann Thorac Surg, 82(4), 1418-9.
• Selzman CH, Bhati RS, Sheridan BC, Stansfield WE, Mill MR (2006). Surgical therapy for heart failure. J Am Coll Surg, 203(2), 226-39; quiz A59-60.
•  Palatinus, Joseph A.; Carroll, Felix A.; Argenton, Andre B.; Quina, Frank H.  An improved characteristic molecular volume parameter for linear solvation energy relationships of acyclic alkanes. Journal of Physical Organic Chemistry (2006),19(11),  725-730.
•  Palatinus, Joseph A.; Sams, Cassandra M.; Beeston, Christopher M.; Carroll, Felix A.; Argenton, Andre B.; Quina, Frank H.  Kinney Revisited: An Improved Group Contribution Method for the Prediction of Boiling Points of Acyclic Alkanes. Industrial & Engineering Chemistry Research  (2006), 45(20),  6860-6863.

2005

• Ionescu-Zanetti C, Shaw RM, Seo J, Jan YN, Jan LY, Lee LP (2005). Mammalian electrophysiology on a microfluidic platform. Proc Natl Acad Sci U S A, 102(26), 9112-7.
• Hong TT, White AJ, Lucchesi BR. Dermatan disulfate (Intimatan) prevents complement-mediated myocardial injury in the human-plasma-perfused rabbit heart. Int Immunopharmacol. 2005 Feb;5(2):381-91. doi: 10.1016/j.intimp.2004.10.013. PubMed PMID: 15652767.
• Hong TT, Huang J, Driscoll E, Lucchesi BR. The antithrombotic effect of melagatran in combination with clopidogrel and/or aspirin (carotid artery primary thrombosis study). J Cardiovasc Pharmacol. 2005 Oct;46(4):526-33. doi: 10.1097/01.fjc.0000179000.93154.e0. PubMed PMID: 16160608.
• Anastasiou-Nana MI, Tsagalou EP, Mavrikakis EM, Siafakas KX, Tsolakis EJ, Drakos SG, Dalianis A, Karelas J, Terrovitis JV, Nanas JN (2005). Myocardial ischaemic preconditioning in the pig has no effect on the ventricular fibrillation and defibrillation thresholds. Resuscitation, 64(3), 373-6.
• Anastasiou-Nana MI, Tsagalou EP, Charitos C, Siafakas KX, Drakos S, Terrovitis JV, Ntalianis A, Doufas A, Mavrikakis J, Nanas JN (2005). Effects of transient myocardial ischemia on the ventricular defibrillation threshold. Pacing Clin Electrophysiol, 28(2), 97-101.
• Drakos SG, Charitos CE, Ntalianis A, Terrovitis JV, Siafakas KX, Dolou P, Pierrakos C, Charitos E, Karelas J, Nanas JN (2005). Comparison of pulsatile with nonpulsatile mechanical support in a porcine model of profound cardiogenic shock. ASAIO J, 51(1), 26-9.
• Bhati RS, Sheridan BC, Mill MR, Selzman CH (2005). Heart transplantation for progressive cardiomyopathy as a manifestation of MELAS syndrome. J Heart Lung Transplant, 24(12), 2286-9.
• Aromolaran AA, Blatter LA (2005). Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. Am J Physiol Cell Physiol, 289(6), C1426-36.
• Chaudhuri D, Alseikhan BA, Chang SY, Soong TW, Yue DT. Developmental activation of calmodulin-dependent facilitation of cerebellar P-type Ca2+ current. J Neurosci. 2005 Sep 7;
• Yilmaz B, MacLeod RS, Punske BB, Taccardi B, Brooks D . Venous catheter based mapping of ectopic epicardial activation: training data set selection for statistical estimation. IEEE Trans Biomed Eng 2005 Nov ; 52 11 : 1823-31

2004

• Tsagalou EP, Anastasiou-Nana MI, Charitos CE, Siafakas CX, Drakos SG, Ntalianis A, Terrovitis JV, Mavrikakis EM, Doufas A, Nanas JN (2004). Time course of fibrillation and defibrillation thresholds after an intravenous bolus of amiodarone–an experimental study. Resuscitation, 61(1), 83-9.
• Nanas JN, Tsolakis E, Terrovitis JV, Eleftheriou A, Drakos SG, Dalianis A, Charitos CE (2004). Moderate systemic hypotension during reperfusion reduces the coronary blood flow and increases the size of myocardial infarction in pigs. Chest, 125(4), 1492-9.
• Zimmerman MA, Reznikov LL, Raeburn CD, Selzman CH (2004). Interleukin-10 attenuates the response to vascular injury. J Surg Res, 121(2), 206-13.
• Colecraft HM, Alseikhan B, Takahashi SX, Chaudhuri D, Mittman S, Yegnasubramanian V, Alvania RS, Johns DC, Marbán E, Yue DT. Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells. J Physiol. 2002 Jun 1;

2003

• Drakos SG, Papamichael CM, Alexopoulos GP, Anastasiou-Nana MI, Stathopoulos JV, Nanas JN (2003). Effects of high doses versus standard doses of enalapril on endothelial cell function in patients with chronic congestive heart failure secondary to idiopathic dilated or ischemic cardiomyopathy. Am J Cardiol, 91(7), 885-8.
• Hong TT, Driscoll EM, White AJ, Sherigill A, Giboulot TA, Lucchesi BR. Glycoprotein IIb/IIIa receptor antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-[[2-([4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] butanoyl]amino)acetyl]amino]propanoic acid dihydrochloride (CRL42796), in combination with aspirin and/or enoxaparin, prevents coronary artery rethrombosis after successful thrombolytic treatment by recombinant tissue plasminogen activator. J Pharmacol Exp Ther. 2003 Aug;306(2):616-23. doi: 10.1124/jpet.103.052886. Epub 2003 May 6. PubMed PMID: 12734394.

• Selzman CH, Netea MG, Zimmerman MA, Weinberg A, Reznikov LL, Grover FL, Dinarello CA (2003). Atherogenic effects of Chlamydia pneumoniae: refuting the innocent bystander hypothesis. J Thorac Cardiovasc Surg, 126(3), 688-93.
• Zimmerman MA, Reznikov LL, Sorensen AC, Selzman CH (2003). Relative contribution of the TNF-alpha receptors to murine intimal hyperplasia. Am J Physiol Regul Integr Comp Physiol, 284(5), R1213-8.
• Zimmerman MA, Selzman CH, Cothren C, Sorensen AC, Raeburn CD, Harken AH (2003). Diagnostic implications of C-reactive protein. Arch Surg, 138(2), 220-4.
• Selzman CH, Zimmerman MA, Campbell DN (2003). ALCAPA in an adult with preserved left ventricular function. J Card Surg, 18(1), 25-8.
• Hennan JK, Willens DE, Driscoll EM Jr, Hong TT, Giboulot T, Lucchesi BR. Prevention of carotid artery thrombosis after oral administration of the glycoprotein IIb/IIIa antagonist CRL42796. J Cardiovasc Pharmacol. 2003 Jul;42(1):71-7. doi: 10.1097/00005344-200307000-00011. PubMed PMID: 12827029.

2002

• Selzman CH, Miller SA, Zimmerman MA, Gamboni-Robertson F, Harken AH, Banerjee A (2002). Monocyte chemotactic protein-1 directly induces human vascular smooth muscle proliferation. Am J Physiol Heart Circ Physiol, 283(4), H1455-61.
• Hennan JK, Hong TT, Willens DE, Driscoll EM, Giboulot TA, Lucchesi BR. Prevention of experimental carotid and coronary artery thrombosis by the glycoprotein IIb/IIIa receptor antagonist CRL42796. Br J Pharmacol. 2002 Jul;136(6):927-37. doi: 10.1038/sj.bjp.0704744. PubMed PMID: 12110617; PubMed Central PMCID: PMC1573408.
• Zimmerman MA, Selzman CH, Reznikov LL, Miller SA, Raeburn CD, Emmick J, Meng X, Harken AH (2002). Lack of TNF-alpha attenuates intimal hyperplasia after mouse carotid artery injury. Am J Physiol Regul Integr Comp Physiol, 283(2), R505-12.
• Albright TN, Zimmerman MA, Selzman CH (2002). Vasopressin in the cardiac surgery intensive care unit. Am J Crit Care, 11(4), 326-30; quiz 331-2.
• Zimmerman MA, Selzman CH, Reznikov LL, Raeburn CD, Barsness K, McIntyre RC Jr, Hamiel CR, Harken AH (2002). Interleukin-11 attenuates human vascular smooth muscle cell proliferation. Am J Physiol Heart Circ Physiol, 283(1), H175-80.
• Zimmerman MA, Albright TN, Raeburn CD, Selzman CH (2002). Vasopressin in cardiovascular patients: therapeutic implications. Expert Opin Pharmacother, 3(5), 505-12.
• Selzman CH, Turner AS, Gaynor JS, Miller SA, Monnet E, Harken AH (2002). Inhibition of intimal hyperplasia using the selective estrogen receptor modulator raloxifene. Arch Surg, 137(3), 333-6.
• Zimmerman MA, Selzman CH, Raeburn CD, Calkins CM, Barsness K, Harken AH (2002). Clinical applications of cardiovascular angiogenesis. J Card Surg, 16(6), 490-7.
• Hennan JK, Hong TT, Shergill AK, Driscoll EM, Cardin AD, Lucchesi BR. Intimatan prevents arterial and venous thrombosis in a canine model of deep vessel wall injury. J Pharmacol Exp Ther. 2002 Jun;301(3):1151-6. doi: 10.1124/jpet.301.3.1151. PubMed PMID: 12023550.

2001

• Nanas S, Nanas J, Kassiotis C, Nikolaou C, Tsagalou E, Sakellariou D, Terovitis I, Papazachou O, Drakos S, Papamichalopoulos A, Roussos C (2001). Early recovery of oxygen kinetics after submaximal exercise test predicts functional capacity in patients with chronic heart failure. Eur J Heart Fail, 3(6), 685-92.
• Drakos SG, AnastasiouNana M, Nanas J (2001). Exacerbation of variant angina by metoprolol resulting in syncope due to transient atrioventricular block. Int J Cardiol, 82, 83-85.
• Ziras N, Rozakou A, Skoura S, Drakos S, Venetsanou V, Tsiggalakis D, Fragaki 924, Giannakakis T, Athanassiou A (2001). Soluble transferrin receptor: An early predicting index of response to epoetin alfa treatment for the prophylaxis of chemotherapy-induced anemia in patients with solid tumors. J BUON, 6, 67-73.
• Shames BD, McIntyre RC Jr, Bensard DD, Pulido EJ, Selzman CH, Reznikov LL, Harken AH, Meng X (2001). Suppression of tumor necrosis factor alpha production by cAMP in human monocytes: dissociation with mRNA level and independent of interleukin-10. J Surg Res, 99(2), 187-93.
• Selzman CH, Miller SA, Harken AH (2001). Therapeutic implications of inflammation in atherosclerotic cardiovascular disease. Ann Thorac Surg, 71(6), 2066-74.
• Selzman CH (2001). Current approaches to therapy for vascular injury. Expert Opin Pharmacother, 2(5), 753-64.
• Selzman CH, Miller SA, Zimmerman MA, Harken AH (2001). The case for beta-adrenergic blockade as prophylaxis against perioperative cardiovascular morbidity and mortality. Arch Surg, 136(3), 286-90.
• Kim SH, Reznikov LL, Stuyt RJ, Selzman CH, Fantuzzi G, Hoshino T, Young HA, Dinarello CA (2001). Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain. J Immunol, 166(1), 148-54.
• Albert AP, Aromolaran AS, Large WA (2001). Agents that increase tyrosine phosphorylation activate a non-selective cation current in single rabbit portal vein smooth muscle cells. J Physiol, 530(Pt 2), 207-17.

2000

• Shames BD, Zallen GS, McIntyre RC Jr, Bensard DD, Pulido EJ, Miller SA, Pomerantz BJ, Selzman CH, Meng X, Harken AH (2000). Chemokines as mediators of diseases related to surgical conditions. Shock, 14(1), 1-7.
• Shames BD, Zallen GS, McIntryre RC Jr, Bensard DD, Pulido EJ, Miller SA, Pomerantz BJ, Selzman CH, Meng X, Harken AH (2000). Chemokines as mediators of diseases related to surgical conditions. Shock, 14(1), 1-7.
• Gaynor JS, Monnet E, Selzman C, Parker D, Kaufman L, Bryant HU, Mallinckrodt C, Wrigley R, Whitehill T, Turner AS (2000). The effect of raloxifene on coronary arteries in aged ovariectomized ewes. J Vet Pharmacol Therapeut, 23(3), 175-9.
• Miller SA, Selzman CH, Shames BD, Barton HA, Johnson SM, Harken AH (2000). Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. J Surg Res, 90(1), 76-81.
• Netea MG, Selzman CH, Kullberg BJ, Galama JM, Weinberg A, Stalenhoef AF, Van der Meer JW, Dinarello CA (2000). Acellular components of Chlamydia pneumoniae stimulate cytokine production in human blood mononuclear cells. Eur J Immunol, 30(2), 541-9.
• Reznikov LL, Shames BD, Barton HA, Selzman CH, Fantuzzi G, Kim SH, Johnson SM, Dinarello CA (2000). Interleukin-1beta deficiency results in reduced NF-kappaB levels in pregnant mice. Am J Physiol Regul Integr Comp Physiol, 278(1), R263-70.
• Gaynor JS, Monnet E, Selzman C, Parker D, Kaufman L, Bryant HU, Mallinckrodt C, Wrigley R, Whitehill T, Turner AS (2000). The effect of raloxifene on coronary arteries in aged ovariectomized ewes. J Vet Pharmacol Therapeut, 23, 175-179.
• Raeburn CD, Cleveland JC, Selzman CH, Harken AH (2000). Ischemic preconditioning in myocardial revascularization with intermittent aortic cross-clamping. J Card Surg, 15, 339-340.
• Aromolaran AS, Albert AP, Large WA (2000). Evidence for myosin light chain kinase mediating noradrenaline-evoked cation current in rabbit portal vein myocytes. J Physiol, 524 Pt 3, 853-63.

1999

• Viswanathan PC, Shaw RM, Rudy Y (1999). Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation, 99(18), 2466-74.
• Ranjan R, Tomaselli GF, Marban E (1999). A novel mechanism of anode-break stimulation predicted by bidomain modeling. Circ Res, 84(2), 153-6.
• Sheridan BC, Dinarello CA, Meldrum DR, Fullerton DA, Selzman CH, McIntyre RC Jr (1999). Interleukin-11 attenuates pulmonary inflammation and vasomotor dysfunction in endotoxin-induced lung injury. Am J Physiol, 277(5), L861-7.
• Cain BS, Meldrum DR, Meng X, Pulido EJ, Shames BD, Selzman CH, Banerjee A, Harken AH (1999). Exogenous calcium preconditions myocardium from patients taking oral sulfonylurea agents. J Surg Res, 86(2), 171-6.
• Pulido EJ, Shames BD, Selzman CH, Barton HA, Banerjee A, Bensard DD, McIntyre RC Jr (1999). Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation. Am J Physiol, 277(4), L769-76.
• Zimmerman MA, Selzman CH, Harken AH (1999). Surgical implications of therapeutic angiogenesis. Surgery, 125(3), 243-9.
• Selzman CH, Shames BD, McIntyre RC Jr, Banerjee A, Harken AH (1999). The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation. Ann Thorac Surg, 67(5), 1227-31; discussion 1231-2.
• Shames BD, Selzman CH, Pulido EJ, Meng X, Meldrum DR, McIntyre RC Jr, Harken AH, Banerjee A (1999). LPS-Induced NF-kappaB activation and TNF-alpha release in human monocytes are protein tyrosine kinase dependent and protein kinase C independent. J Surg Res, 83(1), 69-74.
• Reznikov LL, Fantuzzi G, Selzman CH, Shames BD, Barton HA, Bell H, McGregor JA, Dinarello CA (1999). Utilization of endoscopic inoculation in a mouse model of intrauterine infection-induced preterm birth: role of interleukin 1beta. Biol Reprod, 60(5), 1231-8.
• Selzman CH, Shames BD, Reznikov LL, Miller SA, Meng X, Barton HA, Werman A, Harken AH, Dinarello CA, Banerjee A (1999). Liposomal delivery of purified inhibitory-kappaBalpha inhibits tumor necrosis factor-alpha-induced human vascular smooth muscle proliferation. Circ Res, 84(8), 867-75.
• Zimmerman MA, Selzman CH, Harken AH (1999). Surgical implications of therapeutic angiogenesis. Surgery, 125(3), 243-9.
• Aromolaran AS, Large WA (1999). Comparison of the effects of divalent cations on the noradrenaline-evoked cation current in rabbit portal vein smooth muscle cells. J Physiol, 520 Pt 3, 771-82. Sci U S A, 106(34), 14397-402.

1998

• Ranjan R, Chiamvimonvat N, Thakor NV, Tomaselli GF, Marban E (1998). Mechanism of anode break stimulation in the heart. Biophys J, 74(4), 1850-63.
• Zimmerman MA, Selzman CH, Harken AH (1999). Surgical implications of therapeutic angiogenesis. Surgery, 125(3), 243-9.
• Selzman CH, Gaynor JS, Turner AS, Whitehill TA, Horwitz LD, Harken AH (1998). Estrogen replacement inhibits intimal hyperplasia and the accumulation and effects of transforming growth factor beta1. J Surg Res, 80(2), 380-5.
• Selzman CH, Meldrum DR, Cain BS, Meng X, Shames BD, Ao L, Harken AH (1998). Interleukin-10 inhibits postinjury tumor necrosis factor-mediated human vascular smooth muscle proliferation. J Surg Res, 80(2), 352-6.
• Shames BD, Selzman CH, Meldrum DR, Pulido EJ, Barton HA, Meng X, Harken AH, McIntyre RC Jr (1998). Interleukin-10 stabilizes inhibitory kappaB-alpha in human monocytes. Shock, 10(6), 389-94.
• Selzman CH, Gaynor JS, Turner AS, Johnson SM, Horwitz LD, Whitehill TA, Harken AH (1998). Ovarian ablation alone promotes aortic intimal hyperplasia and accumulation of fibroblast growth factor. Circulation, 98(19), 2049-54.
• Selzman CH, Shames BD, Miller SA, Pulido EJ, Meng X, McIntyre RC Jr, Harken AH (1998). Therapeutic implications of interleukin-10 in surgical disease. Shock, 10(5), 309-18.
• Selzman CH, Whitehill TA, Krupski WC (1998). Thrombophilia and activated protein C resistance. Ann Vasc Surg, 12(6), 601-4.
• Shames BD, Meldrum DR, Selzman CH, Pulido EJ, Cain BS, Banerjee A, Harken AH, Meng X (1998). Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin. Am J Physiol, 275(3), H1084-91.
• Selzman CH, Shames BD, Whitehill TA, Harken AH, McIntyre RC Jr (1998). Class II cytokine receptor ligands inhibit human vascular smooth muscle proliferation. Surgery, 124(2), 318-26; discussion 326-7.
• Meng X, Ao L, Meldrum DR, Cain BS, Shames BD, Selzman CH, Banerjee A, Harken AH (1998). TNF-alpha and myocardial depression in endotoxemic rats: temporal discordance of an obligatory relationship. Am J Physiol, 275(2), R502-8.
• Krupski WC, Selzman CH, Floridia R, Strecker PK, Nehler MR, Whitehill TA (1998). Contemporary management of isolated iliac aneurysms. J Vasc Surg, 28(1), 1-11; discussion 11-3.
• Selzman CH, Shames BD, Miller SA, Pulido EJ, Meng X, McIntyre RC Jr, Harken AH (1998). Therapeutic implications of interleukin-10 in surgical disease. Shock, 10(5), 309-18.
• Shames BD, Selzman CH, Meng X, Meldrum DR, Cain BS, Harken AH (1998). Genes don’t count. Arch Surg, 133(6), 667-9.
• Selzman CH, McIntyre RC Jr, Shames BD, Whitehill TA, Banerjee A, Harken AH (1998). Interleukin-10 inhibits human vascular smooth muscle proliferation. J Mol Cell Cardiol, 30(4), 889-96.
• Selzman CH, Whitehill TA, Shames BD, Pulido EJ, Cain BS, Harken AH (1998). The biology of estrogen-mediated repair of cardiovascular injury. Ann Thorac Surg, 65(3), 868-74.

1997

• Shaw RM, Rudy Y (1997). Ionic mechanisms of propagation in cardiac tissue. Roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling. Circ Res, 81(5), 727-41.
• Shaw RM, Rudy Y (1997). Electrophysiologic effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration. Cardiovasc Res, 35(2), 256-72.
• Shaw RM, Rudy Y (1997). Electrophysiologic effects of acute myocardial ischemia. A mechanistic investigation of action potential conduction and conduction failure. Circ Res, 80(1), 124-38.
• Rudy Y, Shaw RM (1997). Cardiac excitation: an interactive process of ion channels and gap junctions. Adv Exp Med Biol, 430, 269-79.
• Benitah JP, Ranjan R, Yamagishi T, Janecki M, Tomaselli GF, Marban E (1997). Molecular motions within the pore of voltage-dependent sodium channels. Biophys J, 73(2), 603-13.
• Baykal A, Ranjan R, Thakor NV (1997). Estimation of the ventricular fibrillation duration by autoregressive modeling. IEEE Trans Biomed Eng, 44(5), 349-56.
• Thakor NV, Ranjan R, Rajasekhar S, Mower MM (1997). Effect of varying pacing waveform shapes on propagation and hemodynamics in the rabbit heart. Am J Cardiol, 79(6A), 36-43.
• Perez-Garcia MT, Chiamvimonvat N, Ranjan R, Balser JR, Tomaselli GF, Marban E (1997). Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification. Biophys J, 72(3), 989-96.
• Cain BS, Meldrum DR, Selzman CH, Cleveland JC Jr, Meng X, Sheridan BC, Banerjee A, Harken AH (1997). Surgical implications of vascular endothelial physiology. Surgery, 122(3), 516-26.
• Selzman CH, Turner AS, Johnson SM, Cain BS, Harken AH, Whitehill TA (1997). Chronic estrogen replacement inhibits aortic intimal hyperplasia independent of serum lipids. J Card Surg, 12(4), 228-34.
• Meldrum DR, Cleveland JC Jr, Sheridan BC, Rowland RT, Selzman CH, Banerjee A, Harken AH (1997). Alpha-adrenergic activation of myocardial NF kappa B during hemorrhage. J Surg Res, 69(2), 268-76.
• Krupski WC, Selzman CH, Whitehill TA (1997). Unusual causes of mesenteric ischemia. Surg Clin North Am, 77(2), 471-502.

1996

• Chiamvimonvat N, Perez-Garcia MT, Ranjan R, Marban E, Tomaselli GF (1996). Depth asymmetries of the pore-lining segments of the Na+ channel revealed by cysteine mutagenesis. Neuron, 16(5), 1037-47.
• Casaleggio A, Corana A, Ranjan R, Thakor NV (1996). Dimensional analysis of the electrical activity in fibrillating isolated hearts. IJBC, 6, 1547-1561.

1994

• Baykal A, Ranjan R, Thakor NV (1994). Model-based analysis of the ECG during early stages of ventricular fibrillation. J Electrocardiol, 27 Suppl, 84-90.

1995

• Shaw RM, Rudy Y (1995). The vulnerable window for unidirectional block in cardiac tissue: characterization and dependence on membrane excitability and intercellular coupling. J Cardiovasc Electrophysiol, 6(2), 115-31.
• Ranjan R, Thakor NV (1995). Electrical stimulation of cardiac myocytes. Ann Biomed Eng, 23(6), 812-21.

1992

• Clarke LP, Cullom SJ, Shaw R, Reece C, Penney BC, King MA, Silbiger M (1992). Bremsstrahlung imaging using the gamma camera: factors affecting attenuation. J Nucl Med, 33(1), 161-6.