Nora Eccles Harrison Cardiovascular Research & Training Institute

TingTing Hong, MD, PhD

Investigator, Nora Eccles Harrison CVRTI
Assistant Professor of Pharmacology and Toxicology

Hong Lab

Dr. Hong is Associate Professor of Pharmacology & Toxicology and Investigator of Nora Eccles Harrison Cardiovascular Research and Training Institute at the University of Utah.  Dr. Hong received her MD from Peking University in China, and continued there for the Resident Program in Internal Medicine while completing her MS research in hypertension.  She was then moved to the University of Michigan at Ann Arbor for her PhD education, working with Dr. Benedict Lucchesi on the pharmacology of cardiovascular diseases.  After completing her PhD, Dr. Hong joined the Cardiovascular Research Institute at the University of California, San Francisco as a postdoctoral fellow, working with Dr. Robin Shaw investigating calcium channel trafficking in normal and failing cardiomyocytes.  After postdoctoral training, Dr. Hong joined Cedars-Sinai Medical Center and the University of California, Los Angeles as Assistant Professor and later promoted to Associate Professor. 

In 2020, Dr. Hong was recruited to the University of Utah to continue her research program focusing on understanding the regulation and remodeling of membrane microdomains of cardiomyocytes during heart failure progression. The Hong Lab studies how cardiomyocyte surface microdomains are organized to concentrate ion channels and signaling proteins for proper function and regulation in normal and failing hearts. The research includes the mechanisms of scaffolding protein and cytoskeleton-based maintenance of membrane structures and subdomains important in calcium signaling, turnover mechanisms of microdomains, and the mechanisms of heart failure progression. The goal is to identify, at the bench, new molecular and cellular targets that can be translated to develop new therapeutic tools for clinical management of heart failure.