Nora Eccles Harrison Cardiovascular Research & Training Institute

Human Platelets translate messenger RNAs

14 May 2020
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Drs. Elstad, McIntyre, Prescott, Weyrich, and Zimmerman demonstrate that activated human platelets translate messenger RNAs, which are basally present in an extensive and diverse endogenous transcriptome,  to critical biologically-active proteins, fundamentally altering paradigms in platelet biology. 
Weyrich AS, Dixon DA, Ravinder P, Elstad MR, McIntyre TM, Prescott SM, Zimmerman GA. Signal-dependent translation of a regulatory protein, Bcl-3, in activated human platelets. PNAS, 95: 5556-5561,1998