Yan-Ting Shiu, PhD
Investigator Nora Eccles Harrison CVRTI
Professor, Internal Medicine
I obtained my BS degree from National Taiwan University (1994) and PhD degree from Rice University (1999). During 1999-2001, I did my postdoc training at UCSD under Dr. Shu Chien’s mentorship. I came to UU in 2002, spending the first few years in the BME department where classroom teaching and committee services took up most of my time. Dr. Alfred Cheung was instrumental in giving me the opportunity to transfer to DOIM to do research, and was a wonderful mentor, collaborator and division chief/colleagues in the past 14 years.
I am a biomedical engineer by training, with a focus on the vasculature’s mechanobiology and biomechanics. I joined DOIM-Neph in 2010 as a research-track assistant professor and am now a tenured full professor and Dialysis Research Foundation Endowed Chair of Internal Medicine. Since 2010, my research has sharply focused on hemodialysis vascular access (HVA) dysfunction. As a PI, I’ve obtained 5 NIH R01’s, 3 VA Merit Awards, and several foundation awards and industry contracts, all for supporting my research on HVA dysfunction. HVA has extremely aberrant blood flow. After 14 years of working with collaborators, my lab has a unique and the world’s largest HVA blood flow database including HVA in patients and animal models (pig, rat, mouse). We use this information to investigate druggable targets. My lab is a leader in the field of translational research of HVA dysfunction. I also conduct clinical research and am an investigator in the NIDDK-funded HFM Consortium and CRIC Study. In recent year, I’ve started to expand my research program to investigating vascular dysfunctions and the progression of cardiovascular disease in patients with chronic kidney disease, given that cardiovascular disease is the leading cause of death in this population.
