Nora Eccles Harrison Cardiovascular Research & Training Institute

Cardiogenic Shock Causes, Stages, and Treatments

Heart Graphic on Blue Background - What Can Cause Cardiogenic Shock Graphic

Cardiogenic shock is a serious condition that can result in death if medical attention is not sought out quickly. This condition occurs when the heart is no longer able to pump enough blood to meet the needs of your body. When there is not enough blood and oxygen making their way to the organs, it can result in organ failure and eventually death if not treated right away.

This medical issue is more common than a lot of people might imagine. Annually in the United States, there are around 50,000 people who suffer from cardiogenic shock. This is the leading cause of death in people who have a heart attack.

Cardiogenic Shock Causes

Even though it’s the top cause of death in people who have a heart attack, and it is the most common cause of cardiogenic shock, having a heart attack does not always lead to cardiogenic shock.

When someone has a severe heart attack, they may suffer damage to the left ventricle, which is the main pumping chamber for the heart. If this happens, it hampers the body’s ability to pump blood. The left ventricle is often the one that receives the most damage and causes cardiogenic shock. However, it could also happen to the right ventricle.

In addition to heart attacks, you will find other potential causes of cardiogenic shock. There could be inflammation in the heart muscle or an infection in the heart. Those who suffer from an abnormal heart rhythm are at a higher risk of having cardiogenic shock, as well.

Having too much blood around the heart, blood clots, or tears in the valves of the heart could lead to cardiogenic shock, too. Even if someone is considered healthy and has a good heart, an injury to the chest could damage the heart and lead to cardiogenic shock.

Types of Cardiogenic Shock: The Stages

Cardiogenic shock has several stages. The amount of time that each stage lasts can vary from one patient to the next, of course. Additionally, medical attention at earlier stages can sometimes help to curb the problem before it becomes worse.

Some people may have heart disease and other cardiac issues. This might include suffering a heart attack or heart failure but not having signs of cardiogenic shock. These issues don’t always lead to shock.

Those who don’t take steps to reduce their risk at this point may then proceed to what most consider the first stage of cardiogenic shock. This is where they have a lowered blood pressure or heart rate. Essentially, they aren’t pumping enough blood to the organs.

The next stage is when the patient starts to need medicine or medical devices that can help them get blood to their organs.

The following stage is entered if a patient is not responding to those devices or medicine, and they continue to get worse. The patient could then progress to a stage where they enter cardiac arrest and need CPR, a ventilator, or a defibrillator. At this point, it can be difficult for the patient to survive.

Ideally, patients will start to notice that they have issues with their heart as early as possible, so it never progresses beyond those initial stages. However, that’s not often the case.

What Will the Doctors Do?

Diagnosis of Cardiogenic Shock and Emergency Treatment

First, the doctors will need to determine whether the patient has cardiogenic shock or another health issue. There are multiple tests, including lab tests, that doctors can use to provide a proper diagnosis. The treatment will depend on a range of factors including the stage of shock.

The goal is always to ensure that you have enough blood flowing from and to your heart and organs to remain healthy. This might require the use of medications, often provided by IV in cases of emergency. The patient might also have to go on oxygen to increase the amount of O2 in their blood.

Additional Treatment

After emergency medical treatment has been provided, there will likely need to be additional treatment. Again, this will vary based on the cause of the cardiogenic shock. In some cases, it might result in stent placement, heart valve repair, or a bypass. Those who have fluid around the heart will need to have it removed via a needle. This stops the compression of the heart.

Each case is different. Patients and their loved ones will want to speak with the doctors about the available options. Those who feel they may be in danger of suffering cardiogenic shock should start finding ways to reduce that risk. Talk with a doctor about medications to take and lifestyle changes to make.

Cardiovascular Research and Training Institute (CVRTI)

Researchers at the CVRTI use a multidisciplinary approach to study every aspect of cardiogenic shock from the cell to the bedside.  We have Investigators who study the cell response to lack of oxygen (Chaudhuri, Hoareau, Lesniewski, Palatinus, Selzmen)  and ways to preserve heart tissue when blood flow is compromised in cardiogenic shock.  Individual cells are injured when blood flow is lost and receive additional injury when blood flow is restored (termed reperfusion injury) (Hoareau, Shaw).  Keeping individual cells alive in the setting of shock is critical to patient survival. On the other end of the spectrum, our investigators study methods of maintaining the normal heart rhythm as abnormal heart rhythms a can contribute to cardiogenic shock (Aromolaran, Dosdall, MacLeod, Ranjan, Shaw, Tristani).  Our investigators have access to heart tissue from patients who have received heart transplants for cardiogenic shock to study changes in proteins and molecular signals in response to this condition (Drakos, Hong, Shaw).