Drs. Franklin, Warren, and Zaitsev demonstrate mitochondrial metabolism can be regulated by Smyd1, an important modulator of gene expression in the heart.
Warren J, Tracy CM, Miller MR, Makaju A, Szulik MW, Yuzyuk TN, Barton DW, Wang L, GarcĂa J, Sabry AD, Cawley K, Cox J, Yong Hwan Han, Boudina S, Fiehn O, Tucker H, Zaitsev AV, Franklin S. Histone Methyltransferase Smyd1 Regulates Mitochondrial Energetics in the Heart. PNAS,115 (33): E7871-E7880, 2018.