RESEARCH PUBLICATIONS OF 2025

• Bahrami P, Aromolaran KA, Aromolaran AS. Proarrhythmic Lipid Inflammatory Mediators: Mechanisms in Obesity Arrhythmias. J Cell Physiol. 2025 Feb
• Khan MS, Smego D, Li J, Ishidoya Y, Offei E, Ruiz Castillo MS, Hirahara AM, Balmaceda P, Hunter J, Athavale A, Revelo MP, Palatinus JA, Selzman CH, Ranjan R, Hong T, Dosdall DJ, Shaw RM. AAV9-cBIN1 gene therapy rescues chronic heart failure due to ischemic cardiomyopathy in a canine model. Commun Med (Lond). 2025 Mar
• Valdez SE, Taylor LA, Selzman CH, Drakos S, Shaw RM, Palatinus JA. Left Ventricular Unloading With Assist Device Implantation Increases GJA1-20k Expression in Patients With Arrhythmogenic Cardiomyopathy. 2025 Apr
• Dong J, Kwan E, Bergquist JA, Dosdall DJ, DiBella EV, MacLeod RS, Stoddard GJ, Konstantidinis K, Steinberg BA, Bunch TJ, Ranjan R. Left atrial functional changes associated with repeated catheter ablations for atrial fibrillation. 2025 Jan
• Hunt B, Kwan E, Bergquist J, Brundage J, Orkild B, Dong J, Paccione E, Yazaki K, MacLeod RS, Dosdall DJ, Tasdizen T, Ranjan R. Contrastive pretraining improves deep learning classification of endocardial electrograms in a preclinical model. 2025 Jan
• Derks W, Rode J, Collin S, Rost F, Heinke P, Hariharan A, Pickel L, Simonova I, Lázár E, Graham E, Jashari R, Andrä M, Jeppsson A, Salehpour M, Alkass K, Druid H, Kyriakopoulos CP, Taleb I, Shankar TS, Selzman CH, Sadek H, Jovinge S, Brusch L, Frisén J, Drakos S, Bergmann O. A Latent Cardiomyocyte Regeneration Potential in Human Heart Disease. 2025 Jan
• Balmaceda P, Hitzeman TC, Shaw KE, Kolhepp LM, Killeen M, Fang JC, Butler J, Hernandez AF, Hong T, Shaw RM. Design of the First in Human Gene Therapy Trial of TLT-101 for Chronic Heart Failure (FIGHT-HF). 2025 Mar
• Aivalioti E, Georgiopoulos G, Tual-Chalot S, Bampatsias D, Delialis D, Sopova K, Drakos SG, Stellos K, Stamatelopoulos K. Amyloid-beta metabolism in age-related neurocardiovascular diseases. 2025 Jan
• Kyriakopoulos CP, Sideris K, Taleb I, Maneta E, Tseliou E, Aadland J, Baird AS, Bonios MJ, Nelson M, Dranow E, Goodwin ML, Hanff TC, Carter S, Selzman CH, Stehlik J, Wever-Pinzon O, Ramakrishna S, Tumarkin E, Drakos SG. Left Atrial Reverse Remodeling in Patients Supported With Durable Left Ventricular Assist Devices and Clinical Implications. 2025 May
• Hamouche R, Summers SA, Holland WL, Navankasattusas S, Drakos SG, Tseliou E. The role of sphingolipids in heart failure. 2025 May
• Sideris K, Kyriakopoulos CP, Brinker L, Taleb I, Liori S, Hutman-Zahler A, Hendren N, Hall E, Drakos SG, Stehlik J, Fang JC, Drazner MH, Carter S. Advanced Markers for Hemodynamic Monitoring in Cardiogenic Shock and End-Stage Heart Failure: A Mini Review. 2025 May
• Sideris K, Zhang M, Wohlfahrt P, Siu AF, Shen J, Carter S, Kyriakopoulos CP, Taleb I, Wever-Pinzon O, Shah K, Selzman CH, Rodriguez-Correa C, Kapelios C, Brinker L, Alharethi R, Hess R, Drakos SG, Steinberg BA, Fang JC, Kfoury AG, Melenovsky V, Greene T, Spertus JA, Stehlik J. Integration of Patient Reported Quality-of-life Data into Risk Assessment in Heart Failure. 2025 May
• Scott M, Kyriakopoulos CP, Sheffield E, Krauspe E, Sideris K, Taleb I, Maneta E, Tseliou E, Selko S, Hamouche R, Aadland J, Carter SJ, Jones TL, Ou Z, Presson AP, Selzman CH, Tonna JE, Hanff TC, Drakos SG. Application of the Updated Cardiogenic Shock Working Group SCAI Classification for Cardiogenic Shock: A Single-Centre Analysis. 2025 Apr
• Dunlay SM, Pinney SP, Lala A, Stewart GC, McIlvennan C, Wong RP, Morris AA, Pagani FD, Allen LA, Breathett K, Cogswell R, Colvin MM, Cowger JA, Drakos SG, Gelfman LP, Kanwar MK, Kiernan MS, Kittleson MM, Lewis EF, Moazami N, Ogunniyi MO, Pandey A, Rogers JG, Schumacher KR, Slaughter MS, Tedford RJ, Teuteberg J, Valantine HA, DeFilippis EM, Dixon DD, Golbus JR, Gulati G, Hanff TC, Hsiao S, Lewsey SC, McCormick AD, Nayak A, Fenton KN, Longacre LS, Shanbhag SM, Taddei-Peters WC, Stevenson LW. Recognition of the Large Ambulatory C2D Stage of Advanced Heart Failure-A Call to Action. 2025 Apr
• Shen J, Sarwal A, Singh R, Hartsell SE, Wei G, Nevers M, Christensen JC, Takyi A, Katkam N, Derington CG, Deshmukh VG, Boucher RE, Drakos SG, Greene T, Beddhu S. Comparative effectiveness of insulin glargine, glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors in veterans with type 2 diabetes. 2025 Apr
• Kyriakopoulos CP, Taleb I, Sideris K, Maneta E, Hamouche R, Tseliou E, Krauspe E, Selko S, Carter S, Jones TL, Zhang C, Presson AP, Dranow E, Geer L, Stehlik J, Selzman CH, Goodwin ML, Tonna JE, Hanff TC, Drakos SG. Informing Management of Patients Developing Cardiogenic Shock at a Spoke and Being Transferred to a Hub. 2025 Feb
• Valdez SE, Taylor LA, Selzman CH, Drakos SG, Shaw RM, Palatinus JA. Left Ventricular Unloading With Assist Device Implantation Increases GJA1-20k Expression in Patients With Arrhythmogenic Cardiomyopathy. 2025 May
• Silverton NA, Hoareau GL, Kuck K. Cardiopulmonary Bypass and the Kidney: New Evidence for Old Foes. 2025 Jun
• Bia R, Mitchell G, Javan H, Nickel I, Pierce J, Selzman CH, Franklin S. Proteomic Characterization of Cardioprotective Human Acellular Amniotic Fluid. 2025 Feb
• Mia S, Siokatas G, Sidiropoulou R, Hoffman M, Fragkiadakis K, Markopoulou E, Elesawy MI, Roy R, Blair S, Kuwabara Y, Rapushi E, Chaudhuri D, Makarewich CA, Gao E, Koch WJ, Schilling JD, Molkentin JD, Marketou M, Drosatos K. Hepato-cardiac interorgan communication controls cardiac hypertrophy via combined endocrine-autocrine FGF21 signaling. Cell Rep Med. 2025 May
• Rai NK, Eberhardt DR, Balynas AM, MacEwen MJS, Bratt AR, Sancak Y, Chaudhuri D. Mechanism of MCUB-Dependent Inhibition of Mitochondrial Calcium Uptake. 2025 Apr
• Mendes JK, Le JV, Arai AE, Ranjan R, DiBella EVR, Adluru G. Improving ungated steady-state cardiac perfusion using transition bands. 2025 Jul
• Bunch KT, May HT, Knowlton KU, Bair TL, Muhlestein JB, Anderson JL, Ranjan R, Steinberg BA, Bunch TJ. Atrial Fibrillation as a Predictor of Age-Related Macular Degeneration. 2025 May
• Dong J, Ranjan R. Redo Ablation for Atrial Fibrillation Slows Mechanical Function Decrement From Atrial Fibrillation Progression. 2025 Apr
• Hunt B, Kwan E, Bergquist J, Brundage J, Orkild B, Dong J, Paccione E, Yazaki K, MacLeod RS, Dosdall DJ, Tasdizen T, Ranjan R. Contrastive pretraining improves deep learning classification of endocardial electrograms in a preclinical model. 2025 Jan
• Kwan E, Hunt B, Paccione EN, Orkild BA, Bergquist JA, Ishidoya Y, Yazaki K, Mendes JK, DiBella EVR, MacLeod RS, Dosdall DJ, Ranjan R. Functional and Structural Remodeling as Atrial Fibrillation Progresses in a Persistent Atrial Fibrillation Canine Model. 2025 Apr
• Dong J, Ranjan R. Redo Ablation Slows the Decline in Atrial Strain From Natural Progression of Atrial Fibrillation. 2025 Feb
• Dong J, Kwan E, Bergquist JA, Dosdall DJ, DiBella EV, MacLeod RS, Stoddard GJ, Konstantidinis K, Steinberg BA, Bunch TJ, Ranjan R. Left atrial functional changes associated with repeated catheter ablations for atrial fibrillation. 2025 Jan
• He Y, Wei G, Greene T, Imrey PB, Northrup H, Radeva MK, Beck GJ, Gassman JJ, Kraiss LW, Robbin M, Roy-Chaudhury P, Cheung AK, Berceli SA, Shiu YT; Hemodialysis Fistula Maturation (HFM) Study Group. Hemodynamics are associated with subsequent lumen remodeling and clinical maturation of hemodialysis arteriovenous fistula. 2025 Feb
• Chen LJ, Li JY, Nguyen P, Norwich G, Wang Y, Teng D, Shiu YT, Shyy JYJ, Chien S. Pulsatile flow induces chromatin interaction with lamin-associated proteins to enrich H3K9 methylation in endothelial cells. Proc Natl Acad Sci U S A. 2025 Mar
• Cho ME, Brunt VE, Shiu YT, Bunsawat K. Endothelial dysfunction in chronic kidney disease: a clinical perspective. 2025 May
• Beddhu S, Shiu YT. Muscle Wasting and Arteriovenous Fistula Nonmaturation in Kidney Failure. J Am Soc Nephrol. 2025 May
• Vazquez-Padron RI, Shiu YT. Senescent Cells: An Emerging Therapeutic Target for Hemodialysis Fistula Maturation. 2025 Jan
• Somarathna M, Northrup H, Ingle K, Isayeva-Waldrop T, Nguyen NTN, Lose B, Shiu YT, Lee T. Vascular remodeling in arteriovenous fistula treated with PDE5A inhibitors. 2025 May
• M, Goldmuntz E, Deanfield J, Giardini A, Mital S, Russell M, Gaynor JW, Cnota JF, Wagner M, Srivastava D, Bernstein D, Porter GA Jr, Newburger J, Roberts AE, Yandell M, Yost HJ, Tristani-Firouzi M, Kim R, Seidman J, Chung WK, Gelb BD, Seidman CE, Lifton RP, Brueckner M. Recessive genetic contribution to congenital heart disease in 5,424 probands. 2025 Mar
• Sierant MC, Jin SC, Bilguvar K, Morton SU, Dong W, Jiang W, Lu Z, Li B, López-Giráldez F, Tikhonova I, Zeng X, Lu Q, Choi J, Zhang J, Nelson-Williams C, Knight JR, Zhao H, Cao J, Mane S, Sedore SC, Gruber PJ, Lek M, Goldmuntz E, Deanfield J, Giardini A, Mital S, Russell M, Gaynor JW, King E, Wagner M, Srivastava D, Shen Y, Bernstein D, Porter GA Jr, Newburger JW, Seidman JG, Roberts AE, Yandell M, Yost HJ, Tristani-Firouzi M, Kim R, Chung WK, Gelb BD, Seidman CE, Brueckner M, Lifton RP. Genomic analysis of 11,555 probands identifies 60 dominant congenital heart disease genes. Proc Natl Acad Sci U S A. 2025 Apr
• Ward T, Morton SU, Venturini G, Tai W, Jang MY, Gorham J, Delaughter D, Wasson LK, Khazal Z, Homsy J, Gelb BD, Chung WK, Bruneau BG, Brueckner M, Tristani-Firouzi M, DePalma SR, Seidman C, Seidman JG. Modeling <i>SMAD2</i> Mutations in Induced Pluripotent Stem Cells Provides Insights Into Cardiovascular Disease Pathogenesis. 2025 Mar