Did you know your heart relies on tiny proteins to keep it running in top shape? cBIN1 has a critical cardiac role as an essential protein that maintains structure and therefore controls the organization of each of our cardiac muscle cells. Imagine a protein that acts as an internal architectural protein. When that structural protein goes … Read more

Sixty-four million people worldwide will be affected by heart failure, and according to the American Heart Association, 6.2 million adults in the United States are living with (diagnosed and undiagnosed) heart failure right now. Heart failure leads to 1.8 million deaths worldwide annually, and 500,000 of those are in the United States. These figures continue … Read more

Have you ever asked yourself, “How does cardiovascular exercise affect the heart’s health?” Medical professionals always push to include regular cardio in your exercise routine for better heart health, but why? Cardiovascular exercise promotes cardiac metabolism, which is excellent for your heart. Keep reading to see how this process works and what it does for your … Read more

The heart is a muscle, and, like other muscles in the body, it uses chemical energy to power contraction. Adenosine triphosphate (ATP) is the primary source of this energy, and most cardiac ATP (up to 90%) comes from fatty acids, while the remaining ATP comes from lactate, amino acids, ketone bodies, and blood glucose. The … Read more

Ischemic heart disease is a form of heart disease. Usually abbreviated IHD, ischemic heart disease often results from blockages in the arteries of the heart and is marked by the heart not getting sufficient blood flow and oxygen. IHD also affects cardiac metabolism in several ways.Understanding Ischemic Heart DiseaseCauses and MechanismsIn ischemic heart disease, the heart is … Read more

The goal of cardiac metabolism is to produce chemical energy (ATP) to fuel the heart function. By doing so, the heart is able to continuously pump oxygenated blood to the rest of the body. In normal, healthy cardiac metabolism an efficient rate of ATP fuels heart muscle function. In the context of heart failure, cardiac metabolism becomes … Read more

Mitochondria, the energy powerhouses of our cells, are at the center of a growing body of research linking cellular metabolism to the health of the heart. These dynamic organelles do much more than produce ATP; they regulate cell survival, control oxidative stress, and coordinate communication between cellular systems.As cardiovascular disease remains a leading cause of … Read more